Results 51 to 60 of about 351,513 (313)

Quantifying the Rate, Degree, and Heterogeneity of Morphological Change during an Epithelial to Mesenchymal Transition Using Digital Holographic Cytometry

Applied Sciences, 2020
Cells in complex organisms can transition between epithelial and mesenchymal phenotypes during both normal and malignant physiological events. These two phenotypes are not binary, but rather describe a spectrum of cell states along an axis.
Sofia Kamlund, Birgit Janicke, Kersti Alm, Robert L. Judson-Torres, Stina Oredsson   +4 more
doaj   +1 more source

Transforming growth factor-beta targets Formin-like 2 for Angiopoietin-like 4 secretion during the epithelial mesenchymal transition [PDF]

, 2019
Epithelial to Mesenchymal transition (EMT) is a highly dynamic process that plays a crucial role in tumor progression and metastasis. While remodelling of the actin cytoskeleton is a hallmark of EMT, the responsible actin regulating factors are less well
Moussi, Christel Jessica
core   +1 more source

MOESM1 of miR-335-5p inhibits TGF-β1-induced epithelialâ mesenchymal transition in non-small cell lung cancer via ROCK1

, 2019
Additional file 1: Table S1. The sequences of primers involved in our study.
Wenwen Du, Haicheng Tang, Lei, Zhe, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Huang, Jian-An   +6 more
openaire   +1 more source

Integrin α5/ITGA5 Promotes The Proliferation, Migration, Invasion And Progression Of Oral Squamous Carcinoma By Epithelial-Mesenchymal Transition.

Cancer management and research, 2019
Integrin signalling is involved in cell migration, invasion, proliferation and motility. Integrin α5/ITGA5 is a subunit of Integrin and contributes to the activation of Integrin signalling. The potential role of Integrin α5/ITGA5 in oral squamous cancer remains unknown.
Deng,Yun, Wan,Quan, Yan,Wangxiang
openaire   +4 more sources

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Evidence for mesenchymal-epithelial transition associated with mouse hepatic stem cell differentiation.

PLoS ONE, 2011
UnlabelledMesenchymal-epithelial transition events are related to embryonic development, tissue construction, and wound healing. Stem cells are involved in all of these processes, at least in part.
Bin Li, Yun-Wen Zheng, Yuuki Sano, Hideki Taniguchi   +3 more
doaj   +1 more source

Metabolic Regulation of Epithelial to Mesenchymal Transition: Implications for Endocrine Cancer [PDF]

, 2019
York University ...
Bhattacharya, Debasmita, Scimè, Anthony
core   +1 more source

MOESM3 of miR-335-5p inhibits TGF-β1-induced epithelialâ mesenchymal transition in non-small cell lung cancer via ROCK1

, 2019
Additional file 3: Table S2. Clinicopathological features of NSCLC tissues from 30 patients with non-lymph node metastasis and 30 patients with lymph node metastasi.
Wenwen Du, Haicheng Tang, Lei, Zhe, Jianjie Zhu, Yuanyuan Zeng, Zeyi Liu, Huang, Jian-An   +6 more
openaire   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

New insights into the crossroads between EMT and stemness in the context of cancer [PDF]

, 2016
The epithelial-mesenchymal transition (EMT) is an example of cellular plasticity, where an epithelial cell acquires a mesenchymal-like phenotype that increases its migratory and invasive properties. Stemness is the ability of stem cells to proliferate in
Fabregat Romero, Isabel, Malfettone, Andrea, Soukupova, Jitka   +2 more
core   +1 more source