Results 231 to 240 of about 324,947 (241)
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Epithelial-mesenchymal transition in the liver
Gastroentérologie Clinique et Biologique, 2010Epithelial-mesenchymal transition (EMT) is a physiological process occurring in the embryo. In adult organism, EMT could be involved in disease development. In the liver, the possibility that EMT of liver epithelial cells participate to liver fibrosis is increasingly discussed.
D. Firrincielia +5 more
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Epithelial–mesenchymal transition in the skin
Journal of Dermatological Science, 2011Epithelial-mesenchymal transition (EMT) plays important roles not only in the morphogenesis but also in wound repair, tissue fibrosis and cancer progression. Recently, regulatory mechanism of this process has been elaborately elucidated. EMT can be a new therapeutic target for treating skin ulcer, fibrosing alopecia, and malignant cutaneous cancers ...
Motonobu Nakamura, Yoshiki Tokura
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Epithelial–mesenchymal transition in ovarian cancer
Cancer Letters, 2010Ovarian cancer is a highly metastatic disease and the leading cause of death from gynecologic malignancy. Hence, and understanding of the molecular changes associated with ovarian cancer metastasis could lead to the identification of targets for novel therapeutic interventions. The conversion of an epithelial cell to a mesenchymal cell plays a key role
Vergara D +6 more
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SERPINB3 induces epithelial–mesenchymal transition
The Journal of Pathology, 2010AbstractEpithelial–mesenchymal transition is believed to facilitate invasion and metastasis formation of epithelial tumour cells. SERPINB3 is a serine protease inhibitor, physiologically found in normal squamous epithelium but over‐expressed in epithelial tumours and known to inhibit apoptosis.
QUARTA, SANTINA MARIA +10 more
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Models of epithelial–mesenchymal transition
Drug Discovery Today: Disease Models, 2005The spread of cells from the primary neoplasm to distant organs is the most fearsome aspect of cancer. This process of cancer progression denoted as metastasis has exceptional clinical relevance and represents the major reason for the death of cancer patients.
Wolfgang Mikulits, Andreas Eger
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Epithelial–Mesenchymal Transition in Prostatic Disease
Future Oncology, 2015A fully differentiated epithelium of the normal prostate gland allows epithelial cells to de-differentiate into mesenchymal-like derivatives via the process of epithelial-mesenchymal transition (EMT) and redifferentiate via the reverse process, mesenchymal-epithelial transition.
Seth A Broster, Natasha Kyprianou
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Epithelial-mesenchymal transition and cancermetastasis
The Chinese-German Journal of Clinical Oncology, 2011Epithelial-mesenchymal transition (EMT) is initially considered as a physiological phenomenon during the embryogenesis of mammals, as well as a basic biological event maintaining the stability of the vital body. Recent researches indicated that EMT plays a critical role in various tumors progression, through which epithelial cancers invade and ...
Junjian Deng, Ximing Xu
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Epithelial-Mesenchymal Transitions in Cancer Progression
Cells Tissues Organs, 1996Epithelial cells are the most important cell type in the development of human malignancies. More than 90% of all malignant tumors are carcinomas, and thus of epithelial origin. Aberrant growth and the ability to invade the underlying tissues are intrinsic properties of the fatally altered cells.
Beate Brand-Saberi +2 more
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Epithelial-Mesenchymal Transitions and Cancer
Current Genomics, 2002Carver, Ethan A, Gridley, Thomas
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