Results 241 to 250 of about 220,774 (295)

Unraveling the role of HIF2α in melanoma progression and epithelial-mesenchymal transition. [PDF]

Sci Rep
Han Z, Gao Y, Li Z, Liu Z, Zhang J, Jing T, Xv Y, Miao G, Li X, Chen A.   +9 more
europepmc   +1 more source

[Corrigendum] STAT3 activation in HER2‑overexpressing breast cancer promotes epithelial‑mesenchymal transition and cancer stem cell traits

Seyung Chung, Nolan Giehl, Yanyuan Wu, Jaydutt V. Vadgama   +3 more
openalex   +2 more sources

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Smad7 ameliorate small airway remodeling in COPD by modulating epithelial-mesenchymal transition. [PDF]

Tob Induc Dis
Liu X, Sun S, He S, Xie L.
europepmc   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Olivomycin A Targets Epithelial-Mesenchymal Transition, Apoptosis, and Mitochondrial Quality Control in Renal Cancer Cells. [PDF]

Antioxidants (Basel)
Hsieh CY, Liou YF, Shih YT, Tikhomirov AS, Shchekotikhin AE, Chueh PJ.   +5 more
europepmc   +1 more source

S3RL: Enhancing Spatial Single‐Cell Transcriptomics With Separable Representation Learning

Advanced Science, EarlyView.
Separable Spatial Representation Learning (S3RL) is introduced to enhance the reconstruction of spatial transcriptomic landscapes by disentangling spatial structure and gene expression semantics. By integrating multimodal inputs with graph‐based representation learning and hyperspherical prototype modeling, S3RL enables high‐fidelity spatial domain ...
Laiyi Fu, Penglei Wang, Gaoyuan Xu, Jitao Lu, Qinke Peng, Danyang Wu, Hequan Sun   +6 more
wiley   +1 more source

Aldose Reductase Mediated Mitophagy Promotes Epithelial-Mesenchymal Transition of Hepatocytes. [PDF]

Hepat Med
Yan J, Zhao W, Wang H, Zhou L, Li X, Wang G.   +5 more
europepmc   +1 more source

Inner ear hair cells produced in vitro by a mesenchymal-to-epithelial transition

, 2007
Zhengqing Hu, Jeffrey T. Corwin
openalex   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source