Results 91 to 100 of about 1,223,923 (392)

The Epithelial-Immune Crosstalk in Pulmonary Fibrosis

Frontiers in Immunology, 2021
Interactions between the lung epithelium and the immune system involve a tight regulation to prevent inappropriate reactions and have been connected to several pulmonary diseases.
Thomas Planté-Bordeneuve, Charles Pilette, Charles Pilette, Antoine Froidure, Antoine Froidure   +4 more
doaj   +1 more source

Biochemical adaptations of the retina and retinal pigment epithelium support a metabolic ecosystem in the vertebrate eye

bioRxiv, 2017
Here we report multiple lines of evidence for a comprehensive model for retinal energy metabolism. Metabolic flux, locations of key enzymes and our finding that glucose enters the neural retina almost entirely through photoreceptors support a ...
Mark A. Kanow, Michelle M. Giarmarco, Connor S. R. Jankowski, Kristine A. Tsantilas, A. Engel, Jianhai Du, J. Linton, C. Farnsworth, Stephanie R. Sloat, Austin M. Rountree, I. Sweet, Ken J. Lindsay, Edward D. Parker, Susan E. Brockerhoff, M. Sadilek, J. Chao, J. Hurley   +16 more
semanticscholar   +1 more source

Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia. [PDF]

, 2018
Cell division is essential to expand, shape, and replenish epithelia. In the adult small intestine, cells from a common progenitor intermix with other lineages, whereas cell progeny in many other epithelia form contiguous patches.
Castillo-Azofeifa, David, Delling, Markus, Klein, Ophir D, McKinley, Kara L, Royer, Loic A, Schartner, Christoph, Stuurman, Nico, Vale, Ronald D   +7 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Airway Epithelial Dynamics in Allergy and Related Chronic Inflammatory Airway Diseases

Frontiers in Cell and Developmental Biology, 2020
Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic airway diseases. Several environmental and genetic factors affect airway epithelial dynamics leading to activation of inflammatory mechanisms in the ...
Anu Laulajainen-Hongisto, Anu Laulajainen-Hongisto, Sanna Katriina Toppila-Salmi, Sanna Katriina Toppila-Salmi, Annika Luukkainen, Robert Kern   +5 more
doaj   +1 more source

Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]

, 1998
Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R., Brinck, U., Gabius, Hans-Joachim, Korabiowska, M.   +3 more
core   +1 more source

Apoptosis and the Airway Epithelium [PDF]

Journal of Allergy, 2011
The airway epithelium functions as a barrier and front line of host defense in the lung. Apoptosis or programmed cell death can be elicited in the epithelium as a response to viral infection, exposure to allergen or to environmental toxins, or to drugs.
openaire   +3 more sources

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Regulation of interleukin 33/ST2 signaling of human corneal epithelium in allergic diseases

International Journal of Ophthalmology, 2013
AIM: To identify the function of ST2 and explore the role of IL-33/ST2 signaling in regulating the pro-allergic cytokine production in human corneal epithelial cells (HCECs).METHODS: Human corneal tissues and cultured primary HCECs were treated with IL ...
Jing Lin
doaj   +1 more source

Autophagy protein ATG16L1 prevents necroptosis in the intestinal epithelium

Journal of Experimental Medicine, 2017
A variant of the autophagy gene ATG16L1 is associated with Crohn’s disease, an inflammatory bowel disease (IBD), and poor survival in allogeneic hematopoietic stem cell transplant recipients.
Yu Matsuzawa-Ishimoto, Y. Shono, L. E. Gómez, Vanessa M Hubbard-Lucey, M. Cammer, J. Neil, M. Dewan, Sophia R Lieberman, A. Lazrak, Jill M. Marinis, A. Beal, P. Harris, J. Bertin, Chen Liu, Yi Ding, M. Brink, M. Brink, K. Cadwell   +17 more
semanticscholar   +1 more source