Results 111 to 120 of about 929,727 (312)
Regulation of interleukin 33/ST2 signaling of human corneal epithelium in allergic diseases
International Journal of Ophthalmology, 2013 AIM: To identify the function of ST2 and explore the role of IL-33/ST2 signaling in regulating the pro-allergic cytokine production in human corneal epithelial cells (HCECs).METHODS: Human corneal tissues and cultured primary HCECs were treated with IL ...
Jing Lin
doaj +1 more source
A technique for the bacteriologic investigation of the physiologic gingival crevice [PDF]
, 1965 Typewritten.Thesis (M.Sc.D.)--Boston University, March, 1965. Note: Page 111 is missing.Bibliography: p.
Dannenbaum, Richard M. +1 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Understanding the roles of gingival beta-defensins
Journal of Oral Microbiology, 2012 Gingival epithelium produces β-defensins, small cationic peptides, as part of its contribution to the innate host defense against the bacterial challenge that is constantly present in the oral cavity.
Ulvi Kahraman Gursoy +1 more
doaj +1 more source
Localization of Na pumps in the tracheal epithelium of the dog. [PDF]
, 1979 Binding of [3H]ouabain by the dog's tracheal epithelium shows a nonspecific component depending linearly on ouabain concentration, and a specific saturable component with a Km of 10(-7) M.
Basbaum, CB, Widdicombe, JH, Yee, JY
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Long-term culture captures injury-repair cycles of colonic stem cells [PDF]
, 2019 The colonic epithelium can undergo multiple rounds of damage and repair, often in response to excessive inflammation. The responsive stem cell that mediates this process is unclear, in part because of a lack of in vitro models that recapitulate key ...
Chen, Feidi +19 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Ultrastructural alteration of mouse lung by prolonged exposure to mixtures of helium and oxygen [PDF]
, 1975 Observed changes consist mainly of blebbing of capillary endothelium and alveolar epithelium, which is quite possibly indicative of cellular edema; also, there can be observed highly-convoluted basement membrane, alveolar debris, and increased numbers of
Harrison, G. A., Solomon, J. D.
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source