Results 121 to 130 of about 1,205,235 (393)

Effect of Achillea santolina on mice spermatogenesis [PDF]

open access: yes, 2004
Achillea santolina, a common variety of Achillea in Golestan province of Iran has been used in traditional medicine for its anti - inflammatory properties.
Azadbakht, M.   +4 more
core   +1 more source

Rapid fucosylation of intestinal epithelium sustains host-commensal symbiosis in sickness

open access: yesNature, 2014
Systemic infection induces conserved physiological responses that include both resistance and ‘tolerance of infection’ mechanisms. Temporary anorexia associated with an infection is often beneficial, reallocating energy from food foraging towards ...
Joseph M Pickard   +10 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

A intervenção da célula epitelial na asma The role of the epithelial cell in asthma

open access: yesRevista Portuguesa de Pneumologia, 2009
Faz -se uma revisão da intervenção da célula epitelial brônquica na fisiopatologia da asma. O epitelio que reveste as vias respiratórias actua como uma barreira física, separando o meio externo do meio interno pulmonar, controla a permeabilidade ...
Anabela Mota Pinto, Ana Todo-Bom
doaj  

Expression of the neu protooncogene in the mammary epithelium of transgenic mice induces metastatic disease.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1992
Overexpression and amplification of the neu (c-erbB2, ERBB2) protooncogene have been implicated in the development of aggressive human breast cancer. To directly assess the effect of mammary gland-specific expression of the neu protooncogene, transgenic ...
C. T. Guy   +5 more
semanticscholar   +1 more source

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

open access: yesMolecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo   +18 more
wiley   +1 more source

The ESRP1-GPR137 axis contributes to intestinal pathogenesis

open access: yeseLife, 2017
Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager   +24 more
doaj   +1 more source

Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage [PDF]

open access: yes, 2017
Producción CientíficaLimbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain,
Calonge Cano, Margarita   +7 more
core   +2 more sources

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