Results 121 to 130 of about 911,928 (364)
A intervenção da célula epitelial na asma The role of the epithelial cell in asthma
Revista Portuguesa de Pneumologia, 2009 Faz -se uma revisão da intervenção da célula epitelial brônquica na fisiopatologia da asma. O epitelio que reveste as vias respiratórias actua como uma barreira física, separando o meio externo do meio interno pulmonar, controla a permeabilidade ...
Anabela Mota Pinto, Ana Todo-Bom
doaj
DASGAN -- Joint Domain Adaptation and Segmentation for the Analysis of Epithelial Regions in Histopathology PD-L1 Images [PDF]
arXiv, 2019 The analysis of the tumor environment on digital histopathology slides is becoming key for the understanding of the immune response against cancer, supporting the development of novel immuno-therapies. We introduce here a novel deep learning solution to the related problem of tumor epithelium segmentation. While most existing deep learning segmentation
arxiv
Chronic smoke exposure is associated with autophagy in murine Peyer's patches [PDF]
, 2011 INTRODUCTION: Cigarette smoke causes oxidative stress, leading to smoke-induced autophagy in several organs. Autophagy is a homeostatic process regulating the turnover of proteins and cytoplasmatic organelles.
Allais, Liesbeth +5 more
core +1 more source
Molecular Oncology, EarlyView.Consensus molecular subtypes (CMS1‐4) have been identified to study colorectal cancer heterogeneity and serve as potential biomarkers. In this study, we developed and evaluated NanoCMSer, a NanoString‐based classifier using 55 genes, optimized for FF and FFPE to facilitate the clinical evaluation of CMS subtyping.
Arezo Torang +10 more
wiley +1 more source
Predictive modelling of a novel anti-adhesion therapy to combat bacterial colonisation of burn wounds [PDF]
, 2017 As the development of new classes of antibiotics slows, bacterial resistance to existing antibiotics is becoming an increasing problem. A potential solution is to develop treatment strategies with an alternative mode of action. We consider one such strategy: anti-adhesion therapy.
arxiv +1 more source
Bioaccumulation of PCB & DDE methyl sulfones in marine mammals and their interactions with receptor proteins [PDF]
, 2000 PCB and DDE-Methyl sulphone metabolites are the product of enzymatic and bile acid entero hepatic metabolism in the final phase (III) of PCB and DDE detoxification in mammals following hepatic microsomal cytochrome P450-dependent metabolism (phase I) and
Aguilar, A +5 more
core
Molecular Oncology, EarlyView.Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad +13 more
wiley +1 more source
Effect of Achillea santolina on mice spermatogenesis [PDF]
, 2004 Achillea santolina, a common variety of Achillea in Golestan province of Iran has been used in traditional medicine for its anti - inflammatory properties.
Azadbakht, M. +4 more
core +1 more source
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
The ESRP1-GPR137 axis contributes to intestinal pathogenesis
eLife, 2017 Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager +24 more
doaj +1 more source