Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway
Frontiers in Pharmacology, 2021 Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic.
Liang Wang +10 more
doaj +1 more source
A single-cell survey of the small intestinal epithelium
Nature, 2017 Intestinal epithelial cells absorb nutrients, respond to microbes, function as a barrier and help to coordinate immune responses. Here we report profiling of 53,193 individual epithelial cells from the small intestine and organoids of mice, which enabled
Adam L. Haber +20 more
semanticscholar +1 more source
Limbal stem cell transplantation: clinical results, limits, and perspectives [PDF]
, 2018 Limbal stem cell deficiency (LSCD) is a clinical condition characterized by damage of cornea limbal stem cells, which results in an impairment of corneal epithelium turnover and in an invasion of the cornea by the conjunctival epithelium.
Bruscolini, Alice +3 more
core +1 more source
Claudin-2-dependent paracellular channels are dynamically gated
eLife, 2015 Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured.
Christopher R Weber +7 more
doaj +1 more source
More Than Just a Barrier: The Immune Functions of the Airway Epithelium in Asthma Pathogenesis
Frontiers in Immunology, 2020 Allergic bronchial asthma is a chronic disease of the airways that is characterized by symptoms like respiratory distress, chest tightness, wheezing, productive cough, and acute episodes of broncho-obstruction. This symptom-complex arises on the basis of
A. Frey +5 more
semanticscholar +1 more source
Differentiation state-specific mitochondrial dynamic regulatory networks are revealed by global transcriptional analysis of the developing chicken lens. [PDF]
, 2014 The mature eye lens contains a surface layer of epithelial cells called the lens epithelium that requires a functional mitochondrial population to maintain the homeostasis and transparency of the entire lens.
Anastas, Sara +9 more
core +3 more sources
The ESRP1-GPR137 axis contributes to intestinal pathogenesis
eLife, 2017 Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager +24 more
doaj +1 more source
Species- and organ-specificity of secretory proteins derived from human prostate and seminal vesicles [PDF]
, 1990 Polyclonal antibodies against semenogelin (SG) isolated from human seminal vesicle secretion and acid phosphatase (PAP), β‐microseminoprotein (β‐MSP), and Prostate‐Specific Antigen (PSA) derived from human prostatic fluid, as well as a monoclonal ...
Abrahamsson, P. +5 more
core +2 more sources
A single cell atlas of the tracheal epithelium reveals the CFTR-rich pulmonary ionocyte
Nature, 2018 The functions of epithelial tissues are dictated by the types, abundance and distribution of the differentiated cells they contain. Attempts to restore tissue function after damage require knowledge of how physiological tasks are distributed among cell ...
Lindsey W. Plasschaert +7 more
semanticscholar +1 more source
ON THE GROWTH OF EPITHELIUM. [PDF]
JAMA: The Journal of the American Medical Association, 1901 In the following I intend to report upon some experiments which were undertaken as a continuation of former work published in 1898, in theArchiv f. Entwickelungsmechanik.There are reported observations on the growth of epithelium in the coagulated blood during the healing of wounds. I found that epithelium may branch in the blood.
openaire +2 more sources