Results 21 to 30 of about 552,030 (268)

Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

open access: yesCells, 2021
Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik   +3 more
doaj   +1 more source

The expression and localization of V-ATPase and cytokeratin 5 during postnatal development of the pig epididymis [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2020
Objective We examined the localization and expression of H+ pumping vacuolar ATPase (V-ATPase) and cytokeratin 5 (KRT5) in the epididymis of pigs, expressed in clear and basal cells, respectively, during postnatal development.
Yun-Jae Park   +9 more
doaj   +1 more source

The ESRP1-GPR137 axis contributes to intestinal pathogenesis

open access: yeseLife, 2017
Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager   +24 more
doaj   +1 more source

PM10 and Pseudomonas aeruginosa: effects on corneal epithelium

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
PurposeIn vivo data indicate that mouse corneas exposed to PM10 showed early perforation and thinning after infection with Pseudomonas aeruginosa. To understand the mechanisms underlying this finding, we tested the effects of PM10 and the mitochondria ...
Mallika Somayajulu   +4 more
doaj   +1 more source

Key Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
Apicobasal polarity is essential for epithelial cell function, yet the roles of different proteins in its completion is not fully understood. Here, we have studied the role of the polarity protein, CRB2, in human retinal pigment epithelial (RPE) cells ...
Antonio E. Paniagua   +7 more
doaj   +1 more source

The Epithelial-Immune Crosstalk in Pulmonary Fibrosis

open access: yesFrontiers in Immunology, 2021
Interactions between the lung epithelium and the immune system involve a tight regulation to prevent inappropriate reactions and have been connected to several pulmonary diseases.
Thomas Planté-Bordeneuve   +4 more
doaj   +1 more source

Inhaled Dual Phosphodiesterase 3/4 Inhibitors for the Treatment of Patients with COPD: A Short Review

open access: yesInternational Journal of COPD, 2021
Clémence Martin,1,2 Pierre-Régis Burgel,1,2 Nicolas Roche1,2 1AP-HP Centre, Hôpital Cochin, Service de Pneumologie, Paris, France; 2Université de Paris, Institut Cochin, INSERM UMR 1016, Paris, FranceCorrespondence: Nicolas RocheService de Pneumologie ...
Martin C, Burgel PR, Roche N
doaj  

Observation of Dynamic Cellular Migration of the Medial Edge Epithelium of the Palatal Shelf in vitro

open access: yesFrontiers in Physiology, 2019
Palatal fusion is a critical step during palatogenesis. In this fusing interface, the epithelial sheets need to be removed in order to achieve mesenchymal continuity.
Gozo Aoyama   +11 more
doaj   +1 more source

A Keratin 12 Expression-Based Analysis of Stem-Precursor Cells and Differentiation in the Limbal–Corneal Epithelium Using Single-Cell RNA-Seq Data

open access: yesBiology
The corneal epithelium (CE) is spread between two domains, the outer vascularized limbus and the avascular cornea proper. Epithelial cells undergo constant migration from the limbus to the vision-critical central cornea.
J. Mario Wolosin
doaj   +1 more source

Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma

open access: yesFrontiers in Immunology, 2020
Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent breathing problems resulting from airway obstruction and hyperresponsiveness.
Bilal Alashkar Alhamwe   +9 more
doaj   +1 more source

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