Results 21 to 30 of about 663,666 (214)

Adipokine Leptin Co-operates With Mechanosensitive Ca2 +-Channels and Triggers Actomyosin-Mediated Motility of Breast Epithelial Cells

Frontiers in Cell and Developmental Biology, 2021
In postmenopausal women, a major risk factor for the development of breast cancer is obesity. In particular, the adipose tissue-derived adipokine leptin has been strongly linked to tumor cell proliferation, migration, and metastasis, but the underlying ...
Anna Acheva, Tytti Kärki, Niccole Schaible, Ramaswamy Krishnan, Sari Tojkander   +4 more
doaj   +1 more source

Psychological stress disrupts intestinal epithelial cell function and mucosal integrity through microbe and host-directed processes

Gut Microbes, 2022
Psychological stress alters the gut microbiota and predisposes individuals to increased risk for enteric infections and chronic bowel conditions. Intestinal epithelial cells (IECs) are responsible for maintaining homeostatic interactions between the gut ...
Jacob M. Allen, Amy R. Mackos, Robert M. Jaggers, Patricia C. Brewster, Mikaela Webb, Chia-Hao Lin, Chris Ladaika, Ronald Davies, Peter White, Brett R. Loman, Michael T. Bailey   +10 more
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Kerstin N. Euler, Ueffing, Marius, Fröhlich, K.J.H., Stefanie Hauck, Marius Ueffing, Euler, K.N., Fröhlich, Kristina J. H., Kerstin Euler, Claudia Alge-priglinger, Stefanie M. Hauck, Deeg, Cornelia A., Hauck, Stefanie M., Kristina J. H. Fröhlich, Euler, Kerstin N., Cornelia A. Deeg, Christoph Szober, Szober, Christoph M., Hauck, S.M., Ueffing, M., Kristina Fröhlich, Cornelia Deeg, Christoph M. Szober, Szober, C.M., Alge-Priglinger, C.S., Alge-Priglinger, Claudia, Deeg, C.A.   +25 more
core   +1 more source

The Dual Role of the Airway Epithelium in Asthma: Active Barrier and Regulator of Inflammation

Cells, 2023
Chronic airway inflammation is the cornerstone on which bronchial asthma arises, and in turn, chronic inflammation arises from a complex interplay between environmental factors such as allergens and pathogens and immune cells as well as structural cells ...
Andreas Frey, Lars P. Lunding, Michael Wegmann   +2 more
doaj   +1 more source

Direct in vivo gene transfer to the airway epithelium employing adenovirus-polylysine-DNA complexes [PDF]

, 1993
Adenovirus-polylysine-DNA complexes were evaluated for their capacity to accomplish direct in vivo gene transfer to airway epithelium employing a rodent model.
Miller, L., Rømer, M., Wagner, E., Harris, C. E., Hu, P.-C., Wagner, Ernst, Cotten, Matt, Cotten, M., Agarwal, Santosh, Curiel, David T., Agarwal, S., Gao, L., Harris, C., Romer, M., Curiel, D.   +14 more
core   +1 more source

Epithelial Cells and Inflammation in Pulmonary Wound Repair

Cells, 2021
Respiratory diseases are frequently characterised by epithelial injury, airway inflammation, defective tissue repair, and airway remodelling. This may occur in a subacute or chronic context, such as asthma and chronic obstructive pulmonary disease, or ...
Amanda Croasdell Lucchini, Naomi N. Gachanja, Adriano G. Rossi, David A. Dorward, Christopher D. Lucas   +4 more
doaj   +1 more source

Claudin-2-dependent paracellular channels are dynamically gated

eLife, 2015
Intercellular tight junctions form selectively permeable barriers that seal the paracellular space. Trans-tight junction flux has been measured across large epithelial surfaces, but conductance across individual channels has never been measured.
Christopher R Weber, Guo Hua Liang, Yitang Wang, Sudipto Das, Le Shen, Alan S L Yu, Deborah J Nelson, Jerrold R Turner   +7 more
doaj   +1 more source

Aberrant Epithelial Cell Proliferation in Peripheral Airways in Bronchiectasis

Frontiers in Cell and Developmental Biology, 2020
Dilation of bronchi and bronchioles caused by destruction and excessive epithelial remodeling is a characteristic feature of bronchiectasis. It is not known how epithelial progenitor cells contribute to these pathologic conditions in peripheral airways ...
Yang Peng, Yang Peng, Ai-ru Xu, Shi-ying Chen, Yan Huang, Xiao-rong Han, Wei-jie Guan, De-Yun Wang, Nan-shan Zhong   +8 more
doaj   +1 more source

Human β-Defensin 2 and Its Postulated Role in Modulation of the Immune Response

Cells, 2021
Studies described so far suggest that human β-defensin 2 is an important protein of innate immune response which provides protection for the human organism against invading pathogens of bacterial, viral, fungal, as well as parasitical origin. Its pivotal
Martyna Cieślik, Natalia Bagińska, Andrzej Górski, Ewa Jończyk-Matysiak   +3 more
doaj   +1 more source

The expression and localization of V-ATPase and cytokeratin 5 during postnatal development of the pig epididymis [PDF]

Asian-Australasian Journal of Animal Sciences, 2020
Objective We examined the localization and expression of H+ pumping vacuolar ATPase (V-ATPase) and cytokeratin 5 (KRT5) in the epididymis of pigs, expressed in clear and basal cells, respectively, during postnatal development.
Yun-Jae Park, Ji-Hyuk Kim, Hack-Youn Kim, Hee-Bok Park, Juhui Choe, Gye-Woong Kim, Sun-Young Baek, Hak-Jae Chung, Yoo-Jin Park, Bongki Kim   +9 more
doaj   +1 more source