Results 31 to 40 of about 733,921 (302)

The ESRP1-GPR137 axis contributes to intestinal pathogenesis

eLife, 2017
Aberrant alternative pre-mRNA splicing (AS) events have been associated with several disorders. However, it is unclear whether deregulated AS directly contributes to disease.
Lukas Franz Mager, Viktor Hendrik Koelzer, Regula Stuber, Lester Thoo, Irene Keller, Ivonne Koeck, Maya Langenegger, Cedric Simillion, Simona P Pfister, Martin Faderl, Vera Genitsch, Irina Tcymbarevich, Pascal Juillerat, Xiaohong Li, Yu Xia, Eva Karamitopoulou, Ruth Lyck, Inti Zlobec, Siegfried Hapfelmeier, Rémy Bruggmann, Kathy D McCoy, Andrew J Macpherson, Christoph Müller, Bruce Beutler, Philippe Krebs   +24 more
doaj   +1 more source

PM10 and Pseudomonas aeruginosa: effects on corneal epithelium

Frontiers in Cellular and Infection Microbiology, 2023
PurposeIn vivo data indicate that mouse corneas exposed to PM10 showed early perforation and thinning after infection with Pseudomonas aeruginosa. To understand the mechanisms underlying this finding, we tested the effects of PM10 and the mitochondria ...
Mallika Somayajulu, Sharon A. McClellan, Farooq Muhammed, Robert Wright, Linda D. Hazlett   +4 more
doaj   +1 more source

Key Role for CRB2 in the Maintenance of Apicobasal Polarity in Retinal Pigment Epithelial Cells

Frontiers in Cell and Developmental Biology, 2021
Apicobasal polarity is essential for epithelial cell function, yet the roles of different proteins in its completion is not fully understood. Here, we have studied the role of the polarity protein, CRB2, in human retinal pigment epithelial (RPE) cells ...
Antonio E. Paniagua, Antonio E. Paniagua, Alicia Segurado, Jorge F. Dolón, Julián Esteve-Rudd, Almudena Velasco, David S. Williams, Concepción Lillo   +7 more
doaj   +1 more source

The Epithelial-Immune Crosstalk in Pulmonary Fibrosis

Frontiers in Immunology, 2021
Interactions between the lung epithelium and the immune system involve a tight regulation to prevent inappropriate reactions and have been connected to several pulmonary diseases.
Thomas Planté-Bordeneuve, Charles Pilette, Charles Pilette, Antoine Froidure, Antoine Froidure   +4 more
doaj   +1 more source

Inhaled Dual Phosphodiesterase 3/4 Inhibitors for the Treatment of Patients with COPD: A Short Review

International Journal of COPD, 2021
Clémence Martin,1,2 Pierre-Régis Burgel,1,2 Nicolas Roche1,2 1AP-HP Centre, Hôpital Cochin, Service de Pneumologie, Paris, France; 2Université de Paris, Institut Cochin, INSERM UMR 1016, Paris, FranceCorrespondence: Nicolas RocheService de Pneumologie ...
Martin C, Burgel PR, Roche N
doaj  

Observation of Dynamic Cellular Migration of the Medial Edge Epithelium of the Palatal Shelf in vitro

Frontiers in Physiology, 2019
Palatal fusion is a critical step during palatogenesis. In this fusing interface, the epithelial sheets need to be removed in order to achieve mesenchymal continuity.
Gozo Aoyama, Hiroshi Kurosaka, Ayaka Oka, Kohei Nakatsugawa, Sayuri Yamamoto, Safiye Esra Sarper, Safiye Esra Sarper, Yu Usami, Satoru Toyosawa, Toshihiro Inubushi, Yukako Isogai, Takashi Yamashiro   +11 more
doaj   +1 more source

A Keratin 12 Expression-Based Analysis of Stem-Precursor Cells and Differentiation in the Limbal–Corneal Epithelium Using Single-Cell RNA-Seq Data

Biology
The corneal epithelium (CE) is spread between two domains, the outer vascularized limbus and the avascular cornea proper. Epithelial cells undergo constant migration from the limbus to the vision-critical central cornea.
J. Mario Wolosin
doaj   +1 more source

Epigenetic Regulation of Airway Epithelium Immune Functions in Asthma

Frontiers in Immunology, 2020
Asthma is a chronic inflammatory disease of the respiratory tract characterized by recurrent breathing problems resulting from airway obstruction and hyperresponsiveness.
Bilal Alashkar Alhamwe, Bilal Alashkar Alhamwe, Bilal Alashkar Alhamwe, Sarah Miethe, Sarah Miethe, Elke Pogge von Strandmann, Daniel P. Potaczek, Daniel P. Potaczek, Holger Garn, Holger Garn   +9 more
doaj   +1 more source

IL-10 family cytokines in chronic rhinosinusitis with nasal polyps: From experiments to the clinic

Frontiers in Immunology, 2022
Chronic rhinosinusitis with nasal polyps (CRSwNP) is considered a nasal sinus inflammatory disease that can be dominated by immune cells and cytokines. IL-10 family cytokines exert essential functions in immune responses during infection and inflammation.
Lijia Xuan, Lijia Xuan, Nan Zhang, Xiangdong Wang, Xiangdong Wang, Luo Zhang, Luo Zhang, Luo Zhang, Claus Bachert   +8 more
doaj   +1 more source

EGF-induced bronchial epithelial cells drive neutrophil chemotactic and anti-apoptotic activity in asthma [PDF]

, 2013
Chronic damage and repair of the bronchial epithelium are features of asthma. We have previously reported that ex vivo stimulation of normal bronchial epithelial cells with epidermal growth factor (EGF), a key factor of epithelial repair, enhances the ...
Donna E Davies, Cornelius Victoria, Grégory Seumois, Lau, LC, Karl J Staples, Cornelius, Victoria, Dorinsky, P, Victoria Cornelius, Davies Donna E., Dinesh Bagmane (457229), Staples, Karl J., Uddin, Mohib, Ratko Djukanović, Pandurangan Vijayanand, Victoria Cornelius (457230), Lau, Laurie C., Mohib Uddin (457226), Karl J. Staples (457228), Bagmane, Dinesh, Ratko Djukanović (457232), Paul Dorinsky, Pandurangan Vijayanand (277869), Djukanović Ratko, Lau, Laurie C, Grégory Seumois (5656213), Lau Laurie C., Staples, KJ, Vijayanand, P, Vijayanand, Pandurangan, Laurie C. Lau (457227), Seumois, G, Uddin, M, Staples, Karl J, Davies, Donna E, Staples Karl J., Davies, DE, Donna E. Davies (137702), Seumois Grégory, Djukanović, R, Dinesh Bagmane, Djukanović, Ratko, Cornelius, V, Davies, Donna E., Laurie C Lau, Dorinsky Paul, Paul Dorinsky (457231), Dorinsky, Paul, Seumois, Grégory, Bagmane Dinesh, Uddin Mohib, Bagmane, D, Mohib Uddin, Vijayanand Pandurangan   +52 more
core   +2 more sources