Results 31 to 40 of about 552,030 (268)

IL-10 family cytokines in chronic rhinosinusitis with nasal polyps: From experiments to the clinic

Frontiers in Immunology, 2022
Chronic rhinosinusitis with nasal polyps (CRSwNP) is considered a nasal sinus inflammatory disease that can be dominated by immune cells and cytokines. IL-10 family cytokines exert essential functions in immune responses during infection and inflammation.
Lijia Xuan, Lijia Xuan, Nan Zhang, Xiangdong Wang, Xiangdong Wang, Luo Zhang, Luo Zhang, Luo Zhang, Claus Bachert   +8 more
doaj   +1 more source

Description of the Human Penile Urethra Epithelium

Medicina
Background and Objectives: The male urethra is a complex structure that plays a critical role in genitourinary health and function. Despite its importance, histological descriptions of the penile urethra, particularly its epithelial components, remain ...
Matisse Duval, David Brownell, Stéphane Chabaud, Alexis Laungani, Eric Philippe, Stéphane Bolduc   +5 more
doaj   +1 more source

Bronchial Epithelial Cells from Cystic Fibrosis Patients Express a Specific Long Non-coding RNA Signature upon Pseudomonas aeruginosa Infection

Frontiers in Cellular and Infection Microbiology, 2017
Pseudomonas aeruginosa (Pa) is the leading cause of chronic lung infection in Cystic Fibrosis (CF) patients. It is well recognized that CF epithelial cells fail to develop an appropriate response to infection, allowing bacterial colonization and a ...
Viviane Balloy, Remya Koshy, Lea Perra, Harriet Corvol, Harriet Corvol, Michel Chignard, Loïc Guillot, Vinod Scaria, Vinod Scaria   +8 more
doaj   +1 more source

Aspergillus fumigatus is responsible for inflammation in a murine model of chronic obstructive pulmonary disease exacerbation

Respiratory Research
Background In patients with chronic obstructive pulmonary disease (COPD), a sensitization to A. fumigatus has been related to a decline in lung function, but the role of fungal agents in the disease pathogenesis remains unclear.
Alexandra Bouyssi, Alexis Trecourt, Tanguy Déméautis, Florence Persat, Olivier Glehen, Martine Wallon, Gilles Devouassoux, Abderrazzak Bentaher, Jean Menotti   +8 more
doaj   +1 more source

Total bladder replacement with de-epithelialized ileum: experimental study in dogs

International Brazilian Journal of Urology, 2004
OBJECTIVE: To assess the value of the silicone modeler in preventing graft retraction in dogs undergoing bladder replacement with de-epithelialized ileum.
Fábio O. Vilar, Luiz A. P. de Araújo, Salvador V.C. Lima   +2 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Anatomy of cornea and ocular surface

Indian Journal of Ophthalmology, 2018
Important functions of cornea in the eye include protecting the structures inside the eye, contributing to the refractive power of the eye, and focusing light rays on the retina with minimum scatter and optical degradation.
Mittanamalli S Sridhar
doaj   +1 more source

Intestinal Inflammation as a Dysbiosis of Energy Procurement: New Insights into an Old Topic

Gut Microbes, 2021
Inflammatory bowel disease (IBD) coincides with profound shifts in microbiota and host metabolic energy supply and demand. The gastrointestinal epithelium is anatomically positioned to provide a selective barrier between the anaerobic luminal microbiota ...
J. Scott Lee, Ruth X. Wang, Erica E. Alexeev, Sean P. Colgan   +3 more
doaj   +1 more source

Arbutin Ameliorates Murine Colitis by Inhibiting JAK2 Signaling Pathway

Frontiers in Pharmacology, 2021
Background and objective: Abnormal activation of Janus kinase 2 (JAK2) promotes the pathogenesis and progress of inflammatory bowel disease (IBD) by stimulating the cytokine traffic.
Liang Wang, Liang Wang, Yuntao Feng, Jianwen Wang, Tenglong Luo, Xinyue Wang, Mengze Wu, Runxia Wang, Dapeng Chen, Jiyan Li, Jingyu Wang   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source