Results 41 to 50 of about 2,664 (222)

Biomimetic Macrophage Cell Membrane‐Based Nanoparticles for Effective Treatment of Glioblastoma Through Boron Neutron Capture Therapy Combined With Immunotherapy

Advanced Science, EarlyView.
ABSTRACT Glioblastoma multiforme (GBM) remains largely incurable due to the blood‐brain barrier (BBB) and immunosuppressive microenvironment. While boron neutron capture therapy (BNCT) selectively eradicates tumor cells via 10B(n, α)‐7Li reactions, its clinical potential in GBM is unrealized because of the suboptimal pharmacokinetics of conventional ...
Jiawen Chen, Haoyu You, Hefa Huang, Huihui Chai, Ruize Zhu, Yun Guan, Qisheng Tang, Tianwen Li, Shan Jiang, Houshi Xu, Peng Wang, Yue Wang, Maoyuan Sun, Beining Liu, Zhen Li, Yulai Zeng, Weiqiu Ping, Yanlin Teng, Songlin Yan, Qinghui Li, Long Gu, Tao Sun, Zhifeng Shi   +22 more
wiley   +1 more source

[Epithermal neutron capture therapy] [PDF]

, 1993
Development of a 4 mA, 2.5 MeV Tandem Cascade Accelerator (TCA) for the production of neutrons via the [sup 7]Li(p,n)[sup 7]Be nuclear reaction is currently nearing completion at SRL. The TCA is a tandem electrostatic accelerator which uses a high current negative ion source in conjunction with a high current solid state cascade multiplier power supply
openaire   +2 more sources

Quantification of 10B and 11B in Biological Samples in Translational Science and Clinical Applications for Boron Neutron Capture Therapy (BNCT)

Medicinal Research Reviews, EarlyView.
ABSTRACT Boron neutron capture therapy (BNCT) is a targeted radiotherapy that exploits the selective accumulation of the 10B isotope within tumors, followed by irradiation with low‐energy neutrons to induce high linear energy transfer particles with short path lengths, resulting in localized tumor cell destruction while sparing surrounding healthy ...
Christoph Selg, Wolfgang A. G. Sauerwein, Evamarie Hey‐Hawkins   +2 more
wiley   +1 more source

On the optimal energy of epithermal neutron beams for BNCT

Physics in Medicine and Biology, 1999
The optimal neutron energy for the treatment of deep-seated tumours using boron neutron capture therapy is studied by analysing various figures of merit. In particular, analysis of the therapeutic gain as a function of the neutron energy indicates that, with the currently available 10B carriers, the most useful neutrons for the treatment of deep-seated
E. Bisceglie, P. Colangelo, N. Colonna, SANTORELLI, PIETRO, V. Variale   +4 more
openaire   +4 more sources

Multiproxy Chronologies of the Hurd Rock Glacier (Livingston Island, South Shetland Islands, Maritime Antarctica): Between the Late‐Stage Stabilization and Flow Deceleration

Permafrost and Periglacial Processes, EarlyView.
ABSTRACT The Hurd Rock Glacier, located on Livingston Island (South Shetland Islands archipelago, Maritime Antarctica), is a tongue‐shaped feature composed of angular boulders, displaying transverse ridges and furrows, and featuring lobate structures, which are more prominently developed in its frontal sector.
Rosana Menéndez‐Duarte, Jesús Ruiz‐Fernández, Laura Rodríguez‐Rodríguez, José M. Fernández‐Fernández, Vincent Rinterknecht, ASTER Team   +5 more
wiley   +1 more source

Epithermal cosmic-ray neutron (CRN) time series from Voulund Farmland, Harrild Heathland and Gludsted Plantation, Denmark, in 2013-2019

, 2019
Time-series of hourly epithermal neutron intensity estimated from measurements of the bare neutron detector and/or the moderated neutron detector. For all three field sites, the data are collected at ground level (i.e.
Jensen, Karsten Høgh, Looms, Majken Caroline, Andreasen, Mie   +2 more
core   +1 more source

Investigation of thermal neutron detection capability of a CdZnTe detector in a mixed gamma-neutron radiation field

Nukleonika, 2018
The aim of this study was to investigate the thermal neutron measurement capability of a CdZnTe detector irradiated in a mixed gamma-neutron radiation field.
Yücel Haluk, Narttürk R. Bora, Zümrüt Senem, Gedik Gizem, Karadag Mustafa   +4 more
doaj   +1 more source

Transporter‐Associated Therapeutic Efficacy of an SMVT‐Targeted Boron Carrier in Boron Neutron Capture Therapy

Cancer Science, EarlyView.
The transporter‐associated BNCT strategy using BBCIP with or without BPA according to tumor transporter characteristics. BPA showed greater efficacy in LAT1‐dominant F98 glioma, whereas BBCIP was more effective in SMVT‐high CRL1666 tumors, suggesting the potential utility of transporter‐based boron carrier selection in BNCT.
Kenichiro Eza, Kohei Tsujino, Rina Shidoh‐Kazuki, Yoshiki Fujikawa, Hideki Kashiwagi, Gen Futamura, Ryo Hiramatsu, Toshihiro Takami, Masahiko Wanibuchi, Naonori Hu, Hiroki Tanaka, Minoru Suzuki, Kai Nishimura, Shota Tanaka, Hiroyuki Nakamura, Shinji Kawabata   +15 more
wiley   +1 more source

Construction of the WSU Epithermal Neutron Filter [PDF]

, 2002
Moderating material has been installed in the original thermal-neutron filter region of the Washington State University (WSU) TRIGA™ type reactor to produce an epithermal-neutron beam.
Venhuizen, James Robert, Tripard, G., Nigg, David Waler   +2 more
core  

A New Position-Sensitive Transmission Detector for Epithermal Neutron Imaging

, 2009
A new neutron resonant transmission (NRT) detector for epithermal neutron imaging has been designed and built for the Ancient Charm project, which is developing a set of complementary neutron imaging methods for analysis of cultural heritage objects. One
PIETROPAOLO A., SCHULZE R., SENESI R., HAJNAL Z., VAN EIJK W. E., SZENTMIKÓSI L., DE PASCALE M. P., KAMERMANS H., POSTMA Hans, FONTIJN D., KUDEJOVA Peter, KASZTOVSZKY Zs., MALFITANA D., BIRÓ K. T., JOLIE J., BORELLA Alessandro, NAKAMURA T., SCHILLEBEECKX Peter, MATERNA T., PERELLI CIPPO E., FESTA G., BOM V. R., TARDOCCHI M., CAROPPI P. A., GODFREY E., BELGYA T., CATTANEO R., GUTMANN M., CLARIJS Martijn, MOXON M. C., DÚZS K., KIRFEL A., SCHOONEVELD E. M., GORINI G., KIS Z., ARANCIO M. L., ANDREANI C., RADAELLI P. G., JAMES J. A., COX S.M.   +39 more
core   +1 more source