Results 371 to 380 of about 554,474 (398)
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HLA-B21 is not an epitope, but a cluster of different epitopes
Human Immunology, 2015Aim Definition of the anti-HLA-B21 antibody specificity in terms of amino acid sequence properties of the target alleles. Methods Antibody specificities are analysed using single-antigen beads by One Lambda. We define an epitope as a set of amino acid positions that could account for the interaction of HLA alleles with anti-HLA antibodies. We call
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Mass spectrometric epitope mapping.
Mass spectrometry reviews (Print), 2018Mass spectrometric epitope mapping has become a versatile method to precisely determine a soluble antigen's partial structure that directly interacts with an antibody in solution.
K. Opuni +5 more
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Autoimmune epitopes: autoepitopes
Autoimmunity Reviews, 2004The identity of reactants for autoantibodies has been successively refined from whole cellular organelles (immunofluorescence), identified molecules (immunoblot; gene expression libraries), epitope regions (truncated cDNAs; peptide scanning) to contact residues, as described here.
Ian R. Mackay, Merrill J. Rowley
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Food Allergen Epitope Mapping.
Journal of Agricultural and Food Chemistry, 2018With the increased global awareness and rise in food allergies, a multifold interest in food allergens is evident. The presence of undeclared food allergens results in expensive food recalls and increased risks of anaphylaxis for the sensitive ...
Changqi Liu, S. Sathe
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Allergen structures and epitopes
Allergy, 2011To cite this article: Meno KH. Allergen structures and epitopes. Allergy 2011; 66 (Suppl. 95): 19–21.AbstractHuman type 1 hypersensitivity diseases such as allergic rhinoconjunctivitis are characterized by allergen‐specific IgE antibodies produced in allergic individuals after allergen exposure.
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Distinct epitopes on amiloride
American Journal of Physiology-Cell Physiology, 1989Most Na(+)-selective transport proteins are inhibited by the drug amiloride. Studies using amiloride analogues suggest that specific regions of amiloride might participate in binding to receptors on these transport proteins. To determine whether certain domains of this drug are recognized as distinct epitopes, amiloride was coupled to albumin through ...
David G. Warnock +4 more
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Epitope Peptides and Immunotherapy
Current Protein & Peptide Science, 2007Allergic diseases affect atopic individuals, who synthesize specific Immunoglobulins E (IgE) to environmental allergens, usually proteins or glycoproteins. These allergens include grass and tree pollens, indoor allergens such as house dust mites and animal dander, and various foods.
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Mapping the Epitopes of Antibodies
Biotechnology and Genetic Engineering Reviews, 2007(2007). Mapping the Epitopes of Antibodies. Biotechnology and Genetic Engineering Reviews: Vol. 24, No. 1, pp. 1-30.
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Seminars in Oncology, 2006
Variable expression of the HER2 receptor has been implicated in the pathogenesis of a number of malignancies. Many therapeutic modalities have been devised that target the receptor and downstream molecular pathways. The humanized monoclonal antibodies trastuzumab and pertuzumab bind epitopes on the extracellular domain, resulting in cell growth ...
Mark D. Pegram, Sumanta Kumar Pal
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Variable expression of the HER2 receptor has been implicated in the pathogenesis of a number of malignancies. Many therapeutic modalities have been devised that target the receptor and downstream molecular pathways. The humanized monoclonal antibodies trastuzumab and pertuzumab bind epitopes on the extracellular domain, resulting in cell growth ...
Mark D. Pegram, Sumanta Kumar Pal
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Omics, 2015
Proteins embody epitopes that serve as their antigenic determinants. Epitopes occupy a central place in integrative biology, not to mention as targets for novel vaccine, pharmaceutical, and systems diagnostics development.
V. Saravanan, N. Gautham
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Proteins embody epitopes that serve as their antigenic determinants. Epitopes occupy a central place in integrative biology, not to mention as targets for novel vaccine, pharmaceutical, and systems diagnostics development.
V. Saravanan, N. Gautham
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