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In Silico Tools for Predicting Novel Epitopes
Identifying antigens within a pathogen is a critical task to develop effective vaccines and diagnostic methods, as well as understanding the evolution and adaptation to host immune responses. Historically, antigenicity was studied with experiments that evaluate the immune response against selected fragments of pathogens.Barra, Carolina +11 more
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Prediction of Linear B-cell Epitopes
2009The prediction of B-cell epitopes is desirable for designing peptide-based vaccines, or generating antibodies especially if the purified protein is difficult to obtain and immunization has to be performed with protein-derived synthetic peptides. A number of freely available tools predict epitopes from protein sequence or structural information.
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T-Cell Epitope Prediction of Chikungunya Virus
2016There has been a growing demand for vaccines against Chikungunya virus (CHIKV), and epitope-based vaccine is a promising solution. Identification of CHIKV T-cell epitopes is critical to ensure successful trigger of immune response for epitope-based vaccine design.
Christine Loan Ping, Eng +2 more
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Definition of the immunogenic HLA epitopes based on an epitope prediction algorithm
Transplantation Proceedings, 2002A C, Papassavas, C, Stavropoulos-Giokas
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Computational Epitope Prediction
PSI Structural Genomics KnowledgeBase, 2012openaire +1 more source