Results 91 to 100 of about 241,882 (308)
The mechanism of humoral immune response to allogeneic organ transplantation
Вестник трансплантологии и искусственных органов, 2017 The problem of antibody-mediated rejection of donor organ remains extremely relevant. The main targets of the antibodies are mainly donor HLA-antigens (Human Leucocyte Antigens), expressed, in particular, by the cells of graft vascular endothelium.
A. S. Berkos, G. V. Nikolaev
doaj +1 more source
Amino acid composition of epitopes and non-epitopes.
, 2015 Amino acid composition of epitopes and non-epitopes.
Jianzhao Gao (155784) +5 more
core +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Comparison between predicted and validated epitopes.
, 2022 (A) Number of predicted epitopes (score ≥ 0.5 and rank ≤ 0.5) versus validated epitopes per allele. (B) Heatmap showing the family average score (any score, rank ≤ 2) for validated HLA class I epitopes.
Francisco Díez-Fuertes (442408) +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Meloidogyne incognita Surface Antigen Epitopes in Infected Arabidopsis Roots.
, 1999 Surface-coat epitopes of Meloidogyne incognita were detected in root tissues of Arabidopsis thaliana during migration and feeding site formation. A whole-mount root technique was used for immunolocalization of surface coat epitopes in A.
Gravato-Nobre, M. J. +16 more
core
List of epitopes and non-epitopes per category.
, 2018 List of epitopes and non-epitopes per category.
Sebastian Carrasco Pro (5180867) +10 more
core +1 more source
Splicing-associated epitopes identified using ≤300nM.
, 2021 (A) Distribution of the number of candidate tumor-specific splicing-derived neoepitopes (splicing-epitopes) and splicing-affected self-epitopes that would be depleted in the altered isoform (self-epitopes) using ≤300nM to define candidate epitopes.
Judith Pérez-Granado (11442479) +6 more
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source