Results 231 to 240 of about 341,338 (291)

Comparative multi "omics" profiling of <i>Gossypium hirsutum</i> and <i>Gossypium barbadense</i> fibers at high temporal resolution reveals key differences in polysaccharide composition and associated glycosyltransferases. [PDF]

Front Plant Sci
Swaminathan S, Lee Y, Grover CE, DeTemple MF, Mugisha AS, Sichterman LE, Yang P, Xie J, Wendel JF, Szymanski DB, Zabotina OA.   +10 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Presentation of the protective epitope in a Chlamydia muridarum MOMP vaccine is dependent on γ-interferon-inducible lysosomal thiol reductase (GILT). [PDF]

Immunohorizons
Pal S, Johnson RM, Tifrea DF, Cresswell P, de la Maza LM.   +4 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Preclinical Assessment of HLA-A*02:01-Restricted PSMA and STEAP1 Epitopes for Peptide-Based Immunotherapy in Prostate Cancer. [PDF]

Drug Des Devel Ther
Huang Y, Yang Y, Xie Y, Shu Y, Yang S, Long X, Wen Z, Duan X, Fu L, Gu D, Huang T.   +10 more
europepmc   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Rationale for multi-epitope TGFβ vaccination in pancreatic cancer: evidence from immunologic and clinical correlates. [PDF]

Signal Transduct Target Ther
Ruders JH, Ahmad SM, Mortensen REJ, Met Ö, Met Ö, Byrdal M, Chen IM, Theile S, Holmström MO, Andersen MH.   +9 more
europepmc   +1 more source

NS3 epitope-decorated nanoparticles produced in bacteria trigger potent T cell immunity against hepatitis C virus. [PDF]

J Biomed Res
Kuprianov VV, Nikolaeva LI, Stuchinskaya MD, Zykova АA, Ravin NV.   +4 more
europepmc   +1 more source

Reverse vaccinology-based design of a universal multiepitope vaccine against chikungunya virus: Phylogenetic and immunoinformatics approaches. [PDF]

Sci Rep
Hakim MS.
europepmc   +1 more source

Immunoinformatics based designing of a broad-spectrum multi-epitope vaccine against co-infection of human metapneumovirus, respiratory syncytial virus, and influenza A virus. [PDF]

Sci Rep
Li L, Chen Y, Wu S, Wu C, Xie J, Shah A, Xie X, Tan J, Qin Y, Zeng Y, Jan AU, Yang T, Ullah S.   +12 more
europepmc   +1 more source