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Immunology Letters, 2005
We have developed a widely applicable method to construct epitope-peptide gene for epitope-vaccine strategy recently. In this study, we wanted to know whether the predefined spacers between epitopes on a recombinant epitope-peptide impacted the production of epitope-specific antibodies.
Zuqiang, Liu +2 more
openaire +2 more sources
We have developed a widely applicable method to construct epitope-peptide gene for epitope-vaccine strategy recently. In this study, we wanted to know whether the predefined spacers between epitopes on a recombinant epitope-peptide impacted the production of epitope-specific antibodies.
Zuqiang, Liu +2 more
openaire +2 more sources
T-Cell Epitope Processing (The Epitope Flanking Regions Matter)
2009Epitopes presented by major histocompatibility complex (MHC) class I molecules for cytotoxic T-lymphocyte (CTL) recognition are derived mainly from cytosolic proteins. Antigen presentation on the cell surface requires correct processing of epitopes by the proteasome, cytosolic and endoplasmic reticulum (ER) aminopeptidases, efficient TAP transport, and
Alejandra Nacarino, Martinez +2 more
openaire +2 more sources
2000
Abstract The previous two chapters described antigenic variation in a single epitope. In this chapter we develop mathematical models of antigenic variation in multiple epitopes. The resulting ‘Multiple epitope theory’ leads to significant refinements in our understanding of the dynamical interaction between genetically variable ...
Martin A Nowak, Robert M May
openaire +1 more source
Abstract The previous two chapters described antigenic variation in a single epitope. In this chapter we develop mathematical models of antigenic variation in multiple epitopes. The resulting ‘Multiple epitope theory’ leads to significant refinements in our understanding of the dynamical interaction between genetically variable ...
Martin A Nowak, Robert M May
openaire +1 more source
SARS-CoV-2 human T cell epitopes: Adaptive immune response against COVID-19
Cell Host and Microbe, 2021Alba Grifoni, John Sidney, Randi Vita
exaly
SARS-CoV-2 Epitopes Are Recognized by a Public and Diverse Repertoire of Human T Cell Receptors
Immunity, 2020Alina Shomuradova +2 more
exaly
Pathogenic epitopes, heterologous immunity and vaccine design
Nature Reviews Microbiology, 2007John E Greenlee
exaly

