Results 51 to 60 of about 491,390 (408)
Viruses, 2023 Failure of cross-protection among interserotypes and intratypes of foot-and-mouth disease virus (FMDV) is a big threat to endemic countries and their prevention and control strategies.
Qian Li +4 more
doaj +1 more source
Robust prediction of HLA class II epitopes by deep motif deconvolution of immunopeptidomes
Nature Biotechnology, 2019 Predictions of epitopes presented by class II human leukocyte antigen molecules (HLA-II) have limited accuracy, restricting vaccine and therapy design.
Julien Racle +11 more
semanticscholar +1 more source
Frontiers in Neurology, 2023 BackgroundThe detection of myelin oligodendrocyte glycoprotein autoantibodies (MOG-Ab) is essential for the diagnosis of MOG-Ab-associated disease (MOGAD). The clinical implications of different epitopes recognized by MOG-Ab are largely unknown.
Jin Myoung Seok +13 more
doaj +1 more source
PLoS Comput. Biol., 2014 Since its identification in 1983, HIV-1 has been the focus of a research effort unprecedented in scope and difficulty, whose ultimate goals — a cure and a vaccine – remain elusive.
B. Murrell +6 more
semanticscholar +1 more source
CD4+ T-cell responses to Epstein-Barr virus (EBV) latent-cycle antigens and the recognition of EBV-transformed lymphoblastoid cell lines [PDF]
, 2005 There is considerable interest in the potential of Epstein-Barr virus (EBV) latent antigen-specific CD4\(^+\) T cells to act as direct effectors controlling EBV-induced B lymphoproliferations.
Brooks, J. +10 more
core +2 more sources
HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. [PDF]
, 2015 Antiretroviral therapy, antibody and CD8+ T cell-mediated responses targeting human immunodeficiency virus-1 (HIV-1) exert selection pressure on the virus necessitating escape; however, the ability of CD4+ T cells to exert selective pressure remains ...
Allen, S +16 more
core +7 more sources
A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes. [PDF]
, 2018 Human botulism is most commonly caused by botulinum neurotoxin (BoNT) serotypes A, B, and E. For this work, we sought to develop a human monoclonal antibody (mAb)-based antitoxin capable of binding and neutralizing multiple subtypes of BoNT/E.
Brown, Jennifer L +11 more
core +2 more sources
Pteridines, 2007 Functional specificity of a protein is linked to its structure. A growing section of bioinformatics deals with the prediction and visualization of protein 3D structures.
Wiltgen Marco, Tilz Gernot P.
doaj +1 more source
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
, 2018 CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources
Frontiers in Immunology, 2023 The devastating COVID-19 pandemic caused by SARS-CoV-2 and multiple variants or subvariants remains an ongoing global challenge. SARS-CoV-2-specific T cell responses play a critical role in early virus clearance, disease severity control, limiting the ...
Gang Yang +15 more
doaj +1 more source