Results 51 to 60 of about 384,025 (227)

The Major Soybean Allergen Gly m Bd 28K Induces Hypersensitivity Reactions in Mice Sensitized to Cow's Milk Proteins [PDF]

, 2016
Reactions to soy have been reported in a proportion of patients with IgE-mediated cow’s milk allergy (CMA). In this work, we analyzed if Gly m Bd 28K/P28, one of the major soybean allergens, is a cross-reactive allergen with cow milk proteins (CMP).
Candreva, Ángela María, Curciarello, Renata, Docena, Guillermo H., Fossati, Carlos Alberto, Petruccelli, Silvana, Smaldini, Paola Lorena   +5 more
core   +2 more sources

Defining the epichromatin epitope [PDF]

Nucleus, 2017
Epichromatin is identified by immunostaining fixed and permeabilized cells with particular bivalent anti-nucleosome antibodies (mAbs PL2-6 and 1H6). During interphase, epichromatin resides adjacent to the inner nuclear membrane; during mitosis, at the outer surface of mitotic chromosomes.
Travis J. Gould, Katalin Tóth, Norbert Mücke, Jörg Langowski, Alexandra S. Hakusui, Ada L. Olins, Donald E. Olins   +6 more
openaire   +2 more sources

CD4+ Th immunogenicity of the Ascaris spp. secreted products [PDF]

, 2020
Ascaris spp. is a major health problem of humans and animals alike, and understanding the immunogenicity of its antigens is required for developing urgently needed vaccines.
Bertazzon, Miriam, Ebner, Friederike, Freund, Christian, Hartmann, Susanne, Midha, Ankur, Morrison, Eliot, Álvaro-Benito, Miguel   +6 more
core   +1 more source

Interaction Between Virus-Like Particles (VLPs) and Pattern Recognition Receptors (PRRs) From Dendritic Cells (DCs): Toward Better Engineering of VLPs

Frontiers in Immunology, 2020
Virus-like particles (VLPs) have been shown to be strong activators of dendritic cells (DCs). DCs are the most potent antigen presenting cells (APCs) and their activation prompts the priming of immunity mediators based on B and T cells.
Jesús Zepeda-Cervantes, Josué Orlando Ramírez-Jarquín, Luis Vaca, Luis Vaca   +3 more
doaj   +1 more source

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis [PDF]

, 2009
Antibodies to citrulline-modifi ed proteins have a high diagnostic value in rheumatoid arthritis (RA). However, their biological role in disease development is still unclear.
Aho, Andersson, Auger, Baeten, Bella, Bettina Sehnert, Brunsberg, Burkhardt, Burkhardt, Bäcklund, Caspi, Chang, Chapuy-Regaud, Collaborative Computational Project, Number 4, DeLano, Dyson, Emsley, Emsley, Emsley, Estelle Bajtner, Foulquier, Girbal-Neuhauser, Giudicelli, Grab, Guy Serre, Harald Burkhardt, Hill, Hill, Hoffmann, Hüseyin Uysal, Kabsch, Kanazawa, Kidd, Krissinel, Kuhn, Kutty S. Nandakumar, Lefranc, Marjolein M.G.M. Thunnissen, Masson-Bessière, Masson-Bessière, Michaëlsson, Molberg, Murshudov, Nair, Nandakumar, Rantapää-Dahlqvist, Read, Reparon-Schuijt, Rikard Holmdahl, Robert Bockermann, Rosloniec, Schellekens, Schellekens, Schulte, Schwab, Stanfield, Stetefeld, Tarcsa, Uysal, van der Helm-van Mil, Vander Cruyssen, von Delwig, Vossenaar, Vossenaar, Vossenaar, Vossenaar, Winn, Yousfi Monod, Zong, Åke Engström   +69 more
core   +2 more sources

Alpha-fetoprotein is an autoantigen in hepatocellular carcinoma and juvenile Batten disease

Frontiers in Bioscience-Landmark, 2020
Failure of immune tolerance leads to production of autoantibodies to self-antigens. The repertoire of autoantibodies detected in cancer patients can indicate the presence of autoimmune disease.
Roberto Bei, Gerald J. Mizejewski
doaj   +1 more source

The epitope recognized by rituximab [PDF]

Blood, 2006
AbstractRituximab is a monoclonal antibody widely used in the treatment of malignant lymphoma and autoimmunity. Its epitope within the B-cell antigen CD20 is largely unknown. We used phage display libraries to select peptides binding to rituximab. Enriched peptides showed 2 sequence patterns: one motif (CALMIANSC) is related to (170)ANPS(173) within ...
Binder, Mascha, Otto, Florian, Mertelsmann, Roland, Veelken, Hendrik, Trepel, Martin   +4 more
openaire   +4 more sources

Comprehensive Overview of Broadly Neutralizing Antibodies against SARS-CoV-2 Variants

Viruses
Currently, SARS-CoV-2 has evolved into various variants, including the numerous highly mutated Omicron sub-lineages, significantly increasing immune evasion ability. The development raises concerns about the possibly diminished effectiveness of available
Lingyan Cui, Tingting Li, Wenhui Xue, Sibo Zhang, Hong Wang, Hongjing Liu, Ying Gu, Ningshao Xia, Shaowei Li   +8 more
doaj   +1 more source

SARS-CoV-2 epitopes inform future vaccination strategies

Frontiers in Immunology, 2022
All currently approved COVID-19 vaccines utilize the spike protein as their immunogen. SARS-CoV-2 variants of concern (VOCs) contain mutations in the spike protein, enabling them to escape infection- and vaccination-induced immune responses to cause ...
Areez Shafqat, Mohamed H. Omer, Omar Ahmad, Mahnoor Niaz, Humzah S. Abdulkader, Shameel Shafqat, Ali Hassan Mushtaq, Abdullah Shaik, Ahmed N. Elshaer, Junaid Kashir, Junaid Kashir, Khaled Alkattan, Ahmed Yaqinuddin   +12 more
doaj   +1 more source

Immunogenicity of NS4b dengue 3 virus mimotope presented to the immune system as multiple antigen peptide system [PDF]

, 2013
The availability of random peptide libraries displayed on bacteriophage (RPL) has provided a powerful tool for selecting sequences that mimic binding properties of natural antigen epitopes (mimotopes). These mimotopes can be used for vaccine design, drug
Acosta, Armando, Aguilar, Alicia, Alvarez, Mayling, Amin, Nevis, Caballero, Yamira, Camacho, Frank, Díaz, Daiyana, García, Angélica, Guzmán, María Guadalupe, Pupo, Maritza, Reyes, Osvalda, Stott, David I.   +11 more
core   +2 more sources