Results 201 to 210 of about 15,072 (244)

An individual treatment effect approach to predict response to mineralocorticoid receptor antagonists in patients with heart failure and reduced ejection fraction. [PDF]

open access: yesEur J Heart Fail
Kobayashi M   +9 more
europepmc   +1 more source

Ethics and eplerenone

Journal of Medical Ethics, 2012
The use of a placebo arm in clinical trials is unethical if there is an active comparator that is acceptably safe and effective. We argue that reasonable evidence of effectiveness and safety of an inexpensive alternative to an expensive therapy is sufficient to require that the inexpensive therapy be included as a comparator when the expensive therapy ...
Shruti, Gupta   +2 more
openaire   +2 more sources

Eplerenone in hypertension

Expert Opinion on Pharmacotherapy, 2004
Appreciation of the role of aldosterone in cardiovascular and renal disease has increased in the last 50 years. The use of spironolactone was limited by adverse sexual effects, including gynaecomastia. Eplerenone is a newer aldosterone antagonist that is much more selective, with minimal affinity for progesterone and androgenic receptors; therefore ...
openaire   +2 more sources

Eplerenone

Reactions Weekly, 2022
openaire   +2 more sources

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