Results 191 to 200 of about 41,666 (217)
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Tetrahedron, 1964
Abstract New preparative routes to the 13α,17aα-epoxide (II) and the 13β,17aβ-epoxide (III) are described. Boron trifluoride in benzene converts the α-epoxide (II) into a mixture from which five products were isolated, but the β-epoxide (III) gives only the 17aβ-hydroxy-Δ8(14)-olefin (VIII).
James M. Coxon +2 more
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Abstract New preparative routes to the 13α,17aα-epoxide (II) and the 13β,17aβ-epoxide (III) are described. Boron trifluoride in benzene converts the α-epoxide (II) into a mixture from which five products were isolated, but the β-epoxide (III) gives only the 17aβ-hydroxy-Δ8(14)-olefin (VIII).
James M. Coxon +2 more
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Chemistry and Physics of Lipids, 2001
Previously unknown 4,5-epoxy-N-acetyl-sphingosine (1) was synthesized by epoxidation of N-acetyl-sphingosine with 1,1-dimethyldioxirane. A by-product generated by HPLC purification is the tetrahydrofuryl derivative of acetamide (2). Mainly allylic oxidation was observed when natural ceramides were reacted with dimethyldioxirane.
A, Möllenberg, G, Spiteller
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Previously unknown 4,5-epoxy-N-acetyl-sphingosine (1) was synthesized by epoxidation of N-acetyl-sphingosine with 1,1-dimethyldioxirane. A by-product generated by HPLC purification is the tetrahydrofuryl derivative of acetamide (2). Mainly allylic oxidation was observed when natural ceramides were reacted with dimethyldioxirane.
A, Möllenberg, G, Spiteller
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Enantioselectivities of yeast epoxide hydrolases for 1,2-epoxides
Tetrahedron: Asymmetry, 1999Abstract Kinetic resolution of homologous series of unbranched 1,2-epoxyalkanes (C-4 to C-12), 1,2-epoxyalkenes (C-4, C-6 and C-8), a 2,2-dialkylsubstituted epoxide (2-methyl-1,2-epoxyheptane) and a benzyloxy-substituted epoxide (benzyl glycidyl ether) was investigated using resting cells of 10 different yeast strains.
Botes, A.L. +3 more
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ChemInform, 1991
Publisher Summary The method for asymmetric epoxidation of alicyclic alcohols is known as Sharpless. The success of this method initiated much research into other techniques of asymmetric oxidation of alkenes in general and this chapter considers the progress in the area for the last six years.
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Publisher Summary The method for asymmetric epoxidation of alicyclic alcohols is known as Sharpless. The success of this method initiated much research into other techniques of asymmetric oxidation of alkenes in general and this chapter considers the progress in the area for the last six years.
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Reaction of dimesitylsilylene with epoxides. Silanone–epoxide adducts
J. Chem. Soc., Chem. Commun., 1981Dimesitylsilylene, generated by photolysis of 2,2-dimesitylhexamethyltrisilane (1), reacts with epoxides to give dimesitylsilanone–epoxide adducts.
Wataru Ando +2 more
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Vitamin K epoxide reductase activity in the metabolism of epoxides
Biochemical Pharmacology, 1985The importance of vitamin K epoxide reductase for the metabolism of a range of structurally diverse epoxides has been investigated. Vitamin K1 epoxide is reduced by rat liver microsomes at a rate of 0.47 nmoles/g liver/min. The rate of menadione oxide reduction is not significantly higher than the non-enzymatic reduction rate.
W. Wörner +4 more
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Flavanoid epoxides V. Stereochemistry of flavindogenide epoxides
Tetrahedron Letters, 1968Abstract The four possible isomeric flavindogenide (3-arylideneflavanone) epoxides (type III, IV, V and VI) have been synthesized and their configurations assigned on the basis of chemical and spectroscopic data. Suggested mechanisms for the epoxidation reactions are discussed.
K. G. Marathe +6 more
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Asymmetric Epoxidation of Allylic Alcohols: The Sharpless Epoxidation [PDF]
Synthesis, 1986 Cette epoxydation se fait avec l'hydroperoxyde de t-butyle en presence de propanolate-2 de titane IV avec le tartrate de dialkyle chiral; exemples de synthese de composes naturels enantiomeriquement purs par l'intermediaire d'epoxydes obtenus par cette reaction ...
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Halogenated epoxides and related compounds as inhibitors of epoxide hydrase
Archives of Biochemistry and Biophysics, 1980Abstract A variety of chlorinated and fluorinated epoxides and related compounds were synthesized and evaluated as inhibitors of epoxide hydrase. The compounds were tested using chicken liver microsomes and a radiometric assay based on [ 3 H]styrene oxide, and using partially purified chicken liver microsomal epoxide hydrase and a continuous ...
John S.A. Walsh, Robert P. Hanzlik
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Inhibition of liver microsomal epoxide hydrase by cyproheptadine epoxide
Experientia, 1977Cyproheptadine epoxide is a competitive inhibitor or rat liver microsomal epoxide hydrase with an apparent K1-value of 0.75 mM. Cyclobenzaprine and its epoxide stimulate in vitro the activity of this enzyme, whereas cyproheptadine, carbamazepine and carbamazepine epoxide have no effect.
Giorgio Belvedere +5 more
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