Enantioselective synthesis of (+)-petromyroxol, enabled by rhodium-catalyzed denitrogenation and rearrangement of a 1-sulfonyl-1,2,3-triazole [PDF]
, 2015 Petromyroxol is a non-racemic mixture of enantiomeric oxylipids isolated from water conditioned with larval sea lamprey. The (+)-antipode exhibits interesting biological properties but only 1 mg was isolated from >100000 L of water.
Boyer, Alistair
core +2 more sources
Depth‐Customizable 3D Electrode Array for Recording Functional Connectivity in the Brain
Advanced Electronic Materials, EarlyView.In this study, a depth‐adjustable, flexible 3D multi‐shank electrode array that produces precise neural recordings at various brain depths is developed. Integrating 2D flexible electrode arrays with a modular supporting board allowed the insertion depth to be easily adjusted without re‐fabrication.
Minseok Kim +5 more
wiley +1 more source
Angewandte Chemie, EarlyView.A two‐stage dication pool strategy using alkenyl thianthrenium intermediates has been developed for anti‐Markovnikov hydrofunctionalization. This method differs from previous approaches in its reaction mechanism and addresses their most significant limitation, namely, the restricted generality of the nucleophile. The approach has been extended to other
Bence Sóvári +7 more
wiley +2 more sources
Molecules, 2016 Chiral epoxides—such as ethyl and methyl (S)-3-(oxiran-2-yl)propanoates ((S)-1a/1b)—are valuable precursors in many chemical syntheses. Until recently, these compounds were synthesized from glutamic acid in four steps (deamination, reduction, tosylation ...
Aurélien A. M. Peru +6 more
doaj +1 more source
Development of a Novel Epoxide-Containing Trimethylenemethane Precursor for Palladium-Catalyzed Cycloadditions [PDF]
, 2019 Pd(0)-catalyzed trimethylenemethane (TMM) cycloaddition reactions have been used extensively to generate disubstituted 5-membered rings with high levels of regioselectivity, chemoselectivity, and stereoselectivity.
Paterson, Mara
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Reactive precursor particles as synthetic platform for the generation of functional nanoparticles, nanogels, and microgels [PDF]
, 2019 Precise control of the chemical functionality of polymer nanoparticles is a key requirement in tailoring their (dynamic) colloidal properties toward advanced applications.
Gruber, Alexandra +2 more
core +1 more source
Ribozyme‐Catalyzed Site‐Specific Labeling of RNA Using O6‐alkylguanine SNAP‐Tag Substrates
Angewandte Chemie, EarlyView.SNAPR is a ribozyme that repurposes O6‐benzylguanine SNAP‐tag substrates for site‐specific labeling of RNA with bioorthogonal alkyne and azide functional groups, fluorophores or photocrosslinkers. The N1A‐alkylated RNA products were converted to N6A‐modified RNA by Dimroth rearrangement.
Manisha B. Walunj +3 more
wiley +2 more sources
Hemisynthesis and Absolute Configuration of novel 6-pentyl-2H-pyran- 2-one derivatives from Trichoderma spp [PDF]
, 2009 A comparative study of the secondary metabolism of two Trichoderma spp. with that of the Thctf1 transcription factor gene null mutant of Trichoderma harzianum 34 was carried out in order to deepen our knowledge of the biosynthetic pathway and mode of ...
Benitez +40 more
core +2 more sources
Advances in 3D and 4D Printing of Soft Robotics and Their Applications
Advanced Intelligent Systems, EarlyView.This article summarizes the development of 3D‐printed soft robotics in the recent decade. The article discusses the printing capabilities of different additive manufacturing technologies in terms of soft polymers, multimaterial printability, soft robotic printing, and 4D printing.
Hao Liu +5 more
wiley +1 more source
Advances and Challenges in Low‐Temperature Upcycling of Waste Polyolefins via Tandem Catalysis
Angewandte Chemie, EarlyView.This review presents an overview of recent advances in mild catalytic transformations of polyolefins, emphasizing the kinetic and thermodynamic interplay between endothermic C─C bond cleavages and the exothermic formation of new C─H, C─C, and C─O bonds.
Wei Zhang +5 more
wiley +2 more sources