Results 161 to 170 of about 165,305 (402)
The Conversion of Aldrin and Heptachlor to Their Epoxides in Soil1 [PDF]
, 1958 Norman Gannon, J. H. Bigger
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Acute Hypercapnia/Ischemia Alters the Esterification of Arachidonic Acid and Docosahexaenoic Acid Epoxide Metabolites in Rat Brain Neutral Lipids. [PDF]
, 2020 In the brain, approximately 90% of oxylipins are esterified to lipids. However, the significance of this esterification process is not known. In the present study, we (1) validated an aminopropyl solid phase extraction (SPE) method for separating ...
Bazinet, Richard P +7 more
core +1 more source
Angewandte Chemie, EarlyView.Lsd18 is a flavin‐dependent monooxygenase from Streptomyces lasalocidi that performs two enantioselective epoxidations during lasalocid A biosynthesis. X‐ray crystal structures of Lsd18 bound to a substrate and product analogue illuminate how this enzyme performs multiple epoxidations on the same substrate molecule and how it controls stereoselectivity.
Qian Wang +12 more
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ChemCatChem, Volume 15, Issue 1, January 9, 2023., 2023 Epoxidation of ethylene with the cis‐MoO2(acac)2 catalyst and the H2O2 and tert‐butyl hydroperoxide oxidants to ethylene oxide reveals different mechanisms based on density functional theory calculations. H2O2 favors an associative pathway slightly over others while a step‐wise mechanism is preferred for tert‐butyl hydroperoxide.
George Dhimba +2 more
wiley +1 more source
A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012
Journal of Research in Medical Sciences, 2013 Background: Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of ...
Zahra Tolou-Ghamari +3 more
doaj
Journal of Medicinal Chemistry, 2012 Epoxide hydrolases have been detected in prokaryotes and eukaryotes ranging from plants to mammals.1,2, 3 In mammals these include the soluble epoxide hydrolase (sEH), microsomal epoxide hydrolase (mEH), cholesterol epoxide hydrolase, and leukotriene A4 (
Hong C Shen, B. Hammock
semanticscholar +1 more source
ChemCatChem, Volume 15, Issue 1, January 9, 2023., 2023 Manganese oxidation chemistry: In line solution and head space Raman spectroscopy combined with 18O atom tracking reveal a common reactive species in the manganese‐pyridine carboxylic acid catalysed oxidation of alkenes, alkanes and alcohols and unexpected disproportionation of H2O2.
Johann B. Kasper +9 more
wiley +1 more source
Site‐Selective Carbonylation of Azetidines via Copper‐Catalyzed Difluorocarbene Insertion
Angewandte Chemie, EarlyView.We disclose a site‐selective Cu‐catalyzed carbonylation of azetidines promoted by difluorocarbene insertion at low temperature, enabling access to a variety of functionalized γ‐lactams and a therapeutic agent for diabetes (40 examples). This skeletal expansion strategy provides a distinct disconnection approach to synthesize medicinally relevant five ...
Fang Zhou, Tong‐De Tan, Ming Joo Koh
wiley +2 more sources