Results 221 to 230 of about 165,305 (402)

Advances in Cytosolic Delivery of Proteins: Approaches, Challenges, and Emerging Technologies

Chemistry &Biodiversity, EarlyView.
Proteins regulate almost all biological processes, and overcoming the protein's natural membrane inpermeability will provide a unique opportunity for intracellular targeting of related therapeutic proteins. Chemical modification of proteins and different types of delivery vectors can mediate intracellular transport of proteins, providing new ideas for ...
Wenyan Zhang, Huiling Liu, Bingdong Zhu, Wen Li, Xue Han, Jiaojiao Fu, Renjie Luo, Haiyan Wang, Jinxia Wang   +8 more
wiley   +1 more source

Tailored phenyl ureas eradicate drug-resistant <i>Mycobacterium tuberculosis</i> by targeting mycolic acid cell wall assembly. [PDF]

Chem Sci
Mostert D, Braun J, Zimmerman MD, Engelhart CA, Berndl S, Quoika PK, Kany AM, Proietto J, Penalva-Lopez S, Wallach JB, Hirsch AKH, Zacharias M, Schnappinger D, Dartois V, Sieber SA.   +14 more
europepmc   +1 more source

Unexpected Epoxide Formation in the Gas-Phase Photooxidation of Isoprene

Science, 2009
F. Paulot, J. Crounse, H. Kjaergaard, A. Kürten, J. S. St. Clair, J. Seinfeld, P. Wennberg   +6 more
semanticscholar   +1 more source

Studies on Digitalis Glycosides. XXIV. Ring-opening Reaction of 14, 15-Epoxide with Thiocyanic Acid, and Preparation of 3β-Hydroxy-14β, 15β-epithio-5β-card-20(22)-enolide

, 1966
Daisuke Satoh, Mieko Horie, Junko Morita
openalex   +2 more sources

Leveraging machine learning in precision medicine to unveil organochlorine pesticides as predictive biomarkers for thyroid dysfunction. [PDF]

Sci Rep
Shamma S, Hussein MA, El-Nahrery EMA, Shahat A, Shoeib T, Abdelnaser A.   +5 more
europepmc   +1 more source

Inhibition of soluble epoxide hydrolase modulates inflammation and autophagy in obese adipose tissue and liver: Role for omega-3 epoxides

Proceedings of the National Academy of Sciences of the United States of America, 2014
C. López‐Vicario, José Alcaraz-Quiles, Verónica García‐Alonso, Bibiana Rius, S. Hwang, E. Titos, A. Lopategi, B. Hammock, V. Arroyo, J. Clària   +9 more
semanticscholar   +1 more source

Synthesis and evaluation of pseudoglucosinolates (psGSLs) releasing isothiocyanates (ITCs) in the presence of azoreductases

ChemBioChem, Accepted Article.
Naturally occurring isothiocyanates (ITCs) display multiple interesting bioactivities, but their medicinal exploitation is very limited as ITCs are non‐druglike compounds with problematic pharmacokinetic properties. The concept of pseudoglucosinolates (psGSLs) provides a novel prodrug approach for the release of ITCs which can be adjusted to different ...
Aishi Chakrabarti, Charity S. G. Ganskow, Mervic D. Kagho, Claire C. Jimidar, Lorenz Wiese, Neslihan Beyazit, Ulrike Beutling, Magarita Seeger, Silvana Smits, Stella Nyström, Anett Schallmey, Anne Farewell, Mark Brönstrup, Philipp Klahn   +13 more
wiley   +1 more source

Amine-Polyether-Epoxide Nanoplatform-Driven Seed Germination, Plant Growth, and Nutrient Uptake for Sustainable Agriculture. [PDF]

ACS Omega
Fico BA, Andrada HE, Alves FB, da Silva EE, Reinaldi JS, Tavares DC, Squarisi IS, Nuevo LG, Montanha GS, de Carvalho HWP, Vaca Chávez F, Molina EF.   +11 more
europepmc   +1 more source

Covalent Peptide‐Graphene Conjugates for Enhanced Cell Spreading, Osteogenic Differentiation, and Angiogenesis in Bone Defects

ChemBioChem, Accepted Article.
Traumatic bone injury is one of the most common injuries that require surgical intervention, and current treatments suffer severe drawbacks. Modern research in bone regeneration focuses on implants will support and enhance native tissue regeneration. One scaffold material that shows promise is graphene oxide (GO), a 2D nanomaterial made from oxidation ...
Michelle Elise Wolf, Yaxuan Liu, Jason D. Orlando, Jingzhi Zhou, Stefanie Arlene Sydlik   +4 more
wiley   +1 more source

Advances in Catalyst Design for β-Lactone Formation via Ring-Expansion Carbonylation. [PDF]

Molecules
Hasnain A, Ganesan V, Yoon S.
europepmc   +1 more source