Results 91 to 100 of about 8,971 (179)

Effect of N-acetylcysteine in COPD patients with different microsomal epoxide hydrolase genotypes

International Journal of COPD, 2015
Jian-Qing Zhang,1 Jia-Qiang Zhang,1 Hua Liu,2 Zhi-Huan Zhao,1 Li-Zhou Fang,1 Ling Liu,1 Wei-Ping Fu,1 Jing-Kui Shu,1 Jia-Gang Feng,1 Lu-Ming Dai1 1Department of Respiratory Critical Care Medicine, 2Department of Clinical Laboratory, First Affiliated ...
Zhang JQ, Zhang JQ, Liu H, Zhao ZH, Fang LZ, Liu L, Fu WP, Shu JK, Feng JG, Dai LM   +9 more
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DUAL ACTING COX‐2 AND SOLUBLE EPOXIDE HYDROLASE INHIBITOR ATTENUATES GLOMERULAR INJURY IN FOCAL SEGMENTAL GLOMERULAR SCLEROSIS

, 2020
Anna Stavniichuk, Abdul H. Khan, Wojciech K. Jankiewicz, Ashraf El‐Meanawy, Michael M. Yeboah, О. Savchuk, Sung Hee Hwang, Bruce D. Hammock, John D. Imig   +8 more
openalex   +1 more source

Epoxyeicosatrienoic acid (EET)-stimulated angiogenesis is mediated by epoxy hydroxyeicosatrienoic acids (EHETs) formed from COX-2

Journal of Lipid Research, 2019
Epoxyeicosatrienoic acids (EETs) are formed from the metabolism of arachidonic acid by cytochrome P450s. EETs promote angiogenesis linked to tumor growth in various cancer models that is attenuated in vivo by cyclooxygenase 2 (COX-2) inhibitors.
Amy A. Rand, Anita Rajamani, Sean D. Kodani, Todd R. Harris, Lukas Schlatt, Bodgan Barnych, Anthony G. Passerini, Bruce D. Hammock   +7 more
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Synthesis of some piperazine/piperidine amides of chromone-2-carboxylic acid as potential soluble epoxide hydrolase (sEH) inhibitors

, 2023
Tuğçe Gür Maz, H. Burak Caliskan
openalex   +1 more source

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase [PDF]

, 2011
Sung Hee Hwang, Karen Wagner, Christophe Morisseau, Jun‐Yan Liu, Hua Dong, Aaron T. Wecksler, Bruce D. Hammock   +6 more
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0211 Prevention of cardiovascular, renal and metabolic abnormalities by soluble epoxide hydrolase inhibition in a murine model of type 2 diabetes

, 2014
Clothilde Roche, Marie Besnier, R. Cassel, Najah Harouki, David Coquerel, Dominique Guerrot, Lionel Nicol, Sylvanie Renet, Emmanuelle Loizon, Christophe Morisseau, Paul Mulder, Antoine Ouvrard‐Pascaud, Anne‐Marie Madec, Vincent Richard, Jérémy Bellien   +14 more
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5-Bromoindirubin 3′-(O-oxiran-2-ylmethyl)oxime: A long-acting anticancer agent and a suicide inhibitor for epoxide hydrolase

, 2017
Yoshimi Ichimaru, Takeshi Fujii, Hiroaki Saito, Makoto Sano, Taketo Uchiyama, Shinichi Miyairi   +5 more
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Addition of Endothelin A-Receptor Blockade Spoils the Beneficial Effect of Combined Renin-Angiotensin and Soluble Epoxide Hydrolase Inhibition: Studies on the Course of Chronic Kidney Disease in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats [PDF]

, 2019
Věra Čertíková Chábová, Petr Kujal, Zdeňka Vaňourková, Petra Škaroupková, Janusz Sadowski, Elżbieta Kompanowska‐Jezierska, Vladimı́r Tesař, Bruce D. Hammock, John D. Imig, Hana Maxová, Luděk Červenka, Ivana Vaněčková   +11 more
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Immuno-electron-microscopic studies on the subcellular distribution of rat liver epoxide hydrolase and the effect of phenobarbitone and 2-acetamidofluorene treatment [PDF]

, 1982
F. Waechter, P. Bentley, Markus W. Germann, Franz Oesch, W. Stäubli   +4 more
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Brain oxylipin concentrations following hypercapnia/ischemia: effects of brain dissection and dissection time[S]

Journal of Lipid Research, 2019
PUFAs are precursors to bioactive oxylipin metabolites that increase in the brain following CO2-induced hypercapnia/ischemia. It is not known whether the brain-dissection process and its duration also alter these metabolites.
Marie Hennebelle, Adam H. Metherel, Alex P. Kitson, Yurika Otoki, Jun Yang, Kin Sing Stephen Lee, Bruce D. Hammock, Richard P. Bazinet, Ameer Y. Taha   +8 more
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