Results 71 to 80 of about 8,971 (179)

Catalysis With Deep Eutectic Solvents: Challenges and Opportunities

ChemCatChem, Volume 17, Issue 11, June 6, 2025.
Deep eutectic solvents (DESs) are emerging as sustainable alternatives in catalysis, offering tunable properties for diverse chemical transformations. This review explores the dual role of DESs as solvents and catalysts, highlighting advancements in organic chemistry, materials science, CO2 fixation, biomass valorization, polymer degradation, and ...
Eduardo Guzmán
wiley   +1 more source

Active maintenance of endothelial cells prevents kidney fibrosis

Kidney Research and Clinical Practice, 2017
Background: Soluble epoxide hydrolase (sEH) expressed by endothelial cells catalyzes the metabolism of epoxyeicosatrienoic acids (EETs), which are vasoactive agents.
Seung Hee Yang, Yong Chul Kim, Jung Nam An, Jin Hyuk Kim, Juhoh Lee, Hee-Yoon Lee, Joo-Youn Cho, Jin Ho Paik, Yun Kyu Oh, Chun Soo Lim, Yon Su Kim, Jung Pyo Lee   +11 more
doaj   +1 more source

Mother knows worst? Fungal infection enhances corn flavonoid of wogonin to inhibit Conogethes punctiferalis larval growth

Plant Biotechnology Journal, Volume 23, Issue 6, Page 2254-2265, June 2025.
Schematic representation of Trichoderma asperellum infection affects the flavonoid content in corn and influences the gut microbiota and juvenile hormone pathway of Conogethes punctiferalis larvae leading to growth inhibition. Summary Pathogen infection in host plants can alter the attraction and adaptability of herbivorous insects.
Qian Li, Jiayu Li, Kaining Wu, Yue Tong, Aihuan Zhang, Yanli Du   +5 more
wiley   +1 more source

Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolase

Heliyon, 2023
The objective of the present study was to investigate anti-inflammatory effects of disenecionyl cis-khellactone (DK) isolated from Peucedanum japonicum Thunberg, a traditional edible plant, in RAW264.7 cells stimulated with lipopolysaccharide (LPS). Anti-
Ji Hyeon Park, Jang Hoon Kim, Seon Il Jang, Byoung Ok Cho   +3 more
doaj  

Re‐assessment of the risks to public health related to the genotoxicity of styrene present in plastic food contact materials

EFSA Journal, Volume 23, Issue 6, June 2025.
Abstract The EFSA Panel on Food Contact Materials (FCM) was requested by the European Commission to re‐evaluate the potential genotoxicity of styrene after oral exposure and its safety for use in plastic FCM with a specific migration limit (SML) of 40 μg/kg food.
EFSA Panel on Food Contact Materials (FCM), Claude Lambré, Riccardo Crebelli, Maria Da Silva, Konrad Grob, Evgenia Lampi, Maria Rosaria Milana, Marja Pronk, Mario Ščetar, Georgios Theodoridis, Els Van Hoeck, Nadia Waegeneers, Claudia Bolognesi, Emma Di Consiglio, Marcel Mengelers, Zainab Al Harraq, Irene Muñoz Pilar, Sandra Rainieri, Gilles Rivière   +18 more
wiley   +1 more source

CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop

Molecular Metabolism, 2022
Objective: Intra-tumoral expression of the serine hydrolase carboxylesterase 2 (CES2) contributes to the activation of the pro-drug irinotecan in pancreatic ductal adenocarcinoma (PDAC).
Yihui Chen, Michela Capello, Mayrim V. Rios Perez, Jody V. Vykoukal, David Roife, Ya'an Kang, Laura R. Prakash, Hiroyuki Katayama, Ehsan Irajizad, Alia Fleury, Sammy Ferri-Borgogno, Dodge L. Baluya, Jennifer B. Dennison, Kim-Anh Do, Oliver Fiehn, Anirban Maitra, Huamin Wang, Paul J. Chiao, Matthew H.G. Katz, Jason B. Fleming, Samir M. Hanash, Johannes F. Fahrmann   +21 more
doaj  

Role of CYP2C9, CYP2C19 and EPHX Polymorphism in the Pharmacokinetic of Phenytoin: A Study on Uruguayan Caucasian Subjects

Pharmaceuticals, 2017
Phenytoin (PHT) oxidative route leads to its main metabolite p-hydroxyphenytoin (p-HPPH), by means of CYP2C9 and CYP2C19. Formation of p-HPPH proceeds via a reactive arene-oxide intermediate.
Natalia Guevara, Cecilia Maldonado, Manuel Uría, Raquel González, Manuel Ibarra, Silvana Alvariza, Antonella Carozzi, Carlos Azambuja, Pietro Fagiolino, Marta Vázquez   +9 more
doaj   +1 more source

Association of soluble epoxide hydrolase 2 gene with the risk of non-syndromic cleft lip with or without cleft palate in western Han Chinese population. [PDF]

Hua Xi Kou Qiang Yi Xue Za Zhi, 2022
Yang M, Wang Y, Yin B, Zheng Q, Shi B, Jia Z.   +5 more
europepmc   +1 more source

Inhibiting the soluble epoxide hydrolase increases the EpFAs and ERK1/2 expression in the hippocampus of LiCl-pilocarpine post-status epilepticus rat model

, 2021
Weifeng Peng, Yijun Shen, Qiang Wang, Jing Ding, Xin Wang   +4 more
openalex   +1 more source

In Vitro and In Silico Insights into sEH Inhibitors with Amide-Scaffold from the Leaves of Capsicum chinense Jacq.

Computational and Structural Biotechnology Journal, 2018
Two compounds termed 1 and 2 were isolated from the leaves of Capsicum chinense using column chromatography. Their structures were identified as amide scaffolds by analyzing spectroscopic signals.
Jang Hoon Kim, Yeong Deuk Jo, Hyo-Young Kim, Bo-Ram Kim, Bomi Nam   +4 more
doaj