Results 141 to 150 of about 260,645 (332)
Advanced Science, EarlyView.The αvβ3‐mediated SPRC@MPDA‐RGD targets broken endothelial cells and controllably releases SPRC. CSE is then activated to produce endogenous H2S, which inhibits ferritinophagy. In brief, H2S inhibits autophagy by activating the PI3K/Akt/mTOR pathway, thereby suppressing the ferroptosis process mediated by NCOA4, and ultimately promoting the ...
Zhiheng Chen +11 more
wiley +1 more source
Creating a performance-driven system [PDF]
The New York City public school system is in the process of creating the nation's first performance-driven system. Such a system promotes competition, maintains quality, and emphasizes a consistently high level of achievement.
Rudy Crew
core
Development and evaluation of biocompatible inks for the local measurement of oxygen using in vivo EPR [PDF]
, 2004 Nicolas Charlier +2 more
openalex +1 more source
Advanced Science, EarlyView.Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang +9 more
wiley +1 more source
Commentary on 3 papers on issues in value-at-risk modeling and evaulation [PDF]
Bank capital ; Risk ; Bank ...
Beverly Hirtle
core
Light‐Induced Pulsed EPR Dipolar Spectroscopy on a Paradigmatic Hemeprotein [PDF]
, 2019 Maria Giulia Dal Farra +8 more
openalex +1 more source
Chemical Upcycling of Polyphenylene Sulfide at Room Temperature
Advanced Science, EarlyView.Poly(phenylene sulfide) (PPS) is a semi‐crystalline super engineering plastic with exceptional properties. An iron‐photocatalyzed strategy is reported for chemical upcycling of PPS plastics at room temperature using 1,2‐dichloroethane. The method demonstrates remarkable efficiency across diverse PPS resins and post‐consumer composites, even within ...
Boning Gu, Chengliang Li, Xuefeng Jiang
wiley +1 more source
Pro‐ATO/Allicin Liposomes for Dual‐Pathway Targeting of p53‐Mutant Tumors
Advanced Science, EarlyView.Schematic illustration of the “pro‐ATO”/allicin liposomal strategy. Liposomal encapsulation improves the stability and bioavailability of both agents while masking allicin's odor. Upon release in the tumor microenvironment, ATO reactivates structural p53 mutants, and allicin inhibits ATR signaling while releasing H2S, collectively inducing synthetic ...
Xiaoling Xu +11 more
wiley +1 more source
Development of CAST therapy based on the EPR effect: lesson from clinical trials.
, 2018 Yasuhiro Matsumura
openalex +2 more sources