Results 91 to 100 of about 3,240,951 (290)

An Efficient Detection Platform Based on Mesoporous Au@Cr2O3 Particles with Schwarz P Surface for Precise Periodontitis Metabolite Profiling

open access: yesAdvanced Science, EarlyView.
A non‐invasive periodontitis diagnosis platform was developed using Au nanoparticles‐decorated mesoporous Cr2O3 (Au@mCr2O3) particles with Schwarz P surface as matrix for saliva metabolic fingerprinting (SMFs) analysis via MALDI‐MS. With the assistance of machine learning of SMFs, this platform enables efficient diagnosis and the screening of potential
Yue Sun   +9 more
wiley   +1 more source

Hyperpolarization of radicals to increase the sensitivity of photo-induced pulsed EPR techniques

open access: yes, 2022
reservedThe aim of this thesis is the improvement of Pulsed Dipolar Electron Paramagnetic Resonance (EPR) techniques by means of hyperpolarization in order to use them for accurate distance measurements between spin labels in biological systems, and more
LEVORIN, LEONARDO
core  

The spatial effect of protein deuteration on nitroxide spin-label relaxation : Implications for EPR distance measurement [PDF]

open access: yes, 2014
This work was supported by a Wellcome Trust Senior Fellowship (095062) to T.O.-H. The Authors would also like to acknowledge funding from The MRC – United Kingdom, Grant G1100021.Pulsed electron-electron double resonance (PELDOR) coupled with site ...
Ward, Richard   +9 more
core   +1 more source

Inhalable ROS‐Responsive Nanospray Activates PPAR‐γ to Restore Macrophage Mitochondrial Homeostasis and Attenuate Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
A nebulized nanoassembly alleviates radiation‐induced lung injury by reprogramming macrophages through coordinated ROS scavenging, NAD+ replenishment, and PPAR‐γ activation. Redox balance, mitochondrial homeostasis, and immune regulation are restored, revealing a microenvironment‐centered strategy for localized radioprotection.
Mingquan Gao   +11 more
wiley   +1 more source

Unraveling Bone‐Skin Crosstalk Enables miRNA Nanoformulation for Cutaneous Neurovascular Reconstruction in Diabetic Mice

open access: yesAdvanced Science, EarlyView.
This study unravels that bone fracture accelerates diabetic wound healing by releasing exosomal microRNA (miR‐130b‐3p). To mimic this bone‐skin crosstalk, we engineered a self‐assembling agomir‐130b‐3p nanocomplex. Delivered via a photocrosslinkable hydrogel, this bio‐inspired therapy provides sustained localized agomir release.
Tao Shen   +14 more
wiley   +1 more source

Time-resolved EPR investigation on the hyperpolarization of radicals by photoexcited triplet states

open access: yes, 2023
reservedThe purpose of this thesis is to provide a methodology to improve the sensitivity of Pulsed Dipolar Electron Paramagnetic Resonance (EPR) techniques by taking advantage of the spin hyperpolarization phenomenon in order to accurately determine ...
PANAZZOLO, LUCA
core  

On a Conjecture by San Pedro [PDF]

open access: yes, 2013
In a recent paper in European Journal for Philosophy of Science Iñaki San Pedro put forward a conjecture regarding the relationship between no-conspiracy and parameter independence in EPR scenarios; namely, that violation of the former implies violation
Wronski, Leszek
core   +1 more source

The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application

open access: yes, 2021
Chemotherapy for human solid tumors in clinical practice is far from satisfactory. Despite the discovery and synthesis of hundreds of thousands of anticancer compounds targeting various crucial units in cancer cell proliferation and metabolism, the ...
Jun Wu
core   +1 more source

Coordination‐Tuned Iridium Single‐Atom Nanozymes Boost Multienzyme Activity for Colorimetric Sensing

open access: yesAdvanced Science, EarlyView.
Breaking the coordination symmetry of Ir single‐atom sites through asymmetric Ir–N3S1 engineering tailors interfacial electron transfer, oxygen activation, and multienzyme‐like catalytic pathways. Operando spectroscopy and theoretical modeling uncover the atomic‐level origin of activity enhancement, providing a strategy for designing multifunctional ...
Tao Li   +10 more
wiley   +1 more source

Exploiting the Symmetry of the Resonator Mode to Enhance PELDOR Sensitivity. [PDF]

open access: yes, 2014
Pulsed electron paramagnetic resonance (EPR) spectroscopy using microwaves at two frequencies can be employed to measure distances between pairs of paramagnets separated by up to 10 nm.
Mei Wai Fung   +11 more
core   +1 more source

Home - About - Disclaimer - Privacy