Results 41 to 50 of about 15,655 (276)

Characteristic burn temperature markers of bones as revealed by electron paramagnetic resonance

Heritage Science
This research paper presents a novel methodology for determining the burn temperature of archaeological bones using electron paramagnetic resonance (EPR) supported by Fourier Transform Infrared (FTIR) spectroscopy.
Tilen Knaflič, Lea Legan, Fabio Cavalli, Polonca Ropret   +3 more
doaj   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Single‐Atom Pt Anchoring on Self‐Doped ZrO2@G‐C3N4 Nanostructure Enables Efficient Photocatalytic Seawater Hydrogen Evolution

Advanced Science, EarlyView.
Grain‐like Zr3+‐ZrO2 and Pt single atoms are integrated into an S‐scheme Zr3+‐ZrO2@g‐C3N4 heterostructure to enable efficient visible‐light‐driven seawater hydrogen production. The combined effect of Pt single‐atom sites and the S‐scheme charge‐transfer pathway accelerates carrier separation, preserves strong redox ability, and markedly enhances ...
Hezheng Sun, Yifan Guo, Xin Yu, Yajie Tian, Feng Gao, Bin Wang, Yanting Tang, Dani S. Assi, Vellaisamy A. L. Roy   +8 more
wiley   +1 more source

The digital stethoscope: Why Switzerland's Electronic Health Record requires citizen testing

Swiss Medical Weekly
  Switzerland's Electronic Patient Record (EPR) system faces a critical adoption crisis: less than 2% of the population has opened an account despite years of investment. To understand this failure from the citizen's perspective, we launched the first “
Barbara C. Biedermann, Peter Grolimund, Bruno Wildhaber, Ernst Hafen   +3 more
doaj   +1 more source

All-atom molecular dynamics simulations of spin labelled double and single-strand DNA for EPR studies [PDF]

, 2018
We report the first application of fully atomistic molecular dynamics (MD) simulations to the prediction of electron paramagnetic resonance (EPR) spectra of spin labelled DNA.
Danilane, Linda, C. Prior, L. Danilāne, Oganesyan, Vasily S., V. S. Oganesyan, Prior, Christopher C.   +5 more
core   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

Nanodrug Delivery Systems Modulate Tumor Vessels to Increase the Enhanced Permeability and Retention Effect

, 2021
The use of nanomedicine for antitumor therapy has been extensively investigated for a long time. Enhanced permeability and retention (EPR) effect-mediated drug delivery is currently regarded as an effective way to bring drugs to tumors, especially ...
Yanzuo Chen, Dong Huang, Leaf Huang, Lingna Sun   +3 more
core   +1 more source

High-field/High-frequency EPR Spectroscopy in Protein Research: Principles and Examples [PDF]

, 2023
During the last decades, the combined efforts of biologists, chemists, and physicists in developing high-field/high-frequency EPR techniques and applying them to functional proteins have demonstrated that this type of magnetic resonance spectroscopy is ...
Möbius, Klaus, Savitsky, Anton
core   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

Quantitative comparison of different iron forms in the temporal cortex of Alzheimer patients and control subjects

Scientific Reports, 2018
We present a quantitative study of different molecular iron forms found in the temporal cortex of Alzheimer (AD) patients. Applying the methodology we developed in our previous work, we quantify the concentrations of non-heme Fe(III) by Electron ...
Marjolein Bulk, Louise van der Weerd, Wico Breimer, Nikita Lebedev, Andrew Webb, Jelle J. Goeman, Roberta J. Ward, Martina Huber, Tjerk H. Oosterkamp, Lucia Bossoni   +9 more
doaj   +1 more source