Results 61 to 70 of about 15,655 (276)

Evaluating Coastal Erosion and Accretion Along Batu Ferringhi Beach with Digital Shoreline Analysis System [PDF]

open access: yesBIO Web of Conferences
Coastal areas face significant challenges due to climate change, particularly through intensified wave action, which contributes to alterations in shoreline dynamics.
Ridzuan Nurfairunnajiha
doaj   +1 more source

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

open access: yesAdvanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral   +7 more
wiley   +1 more source

Personalized Reimbursement Model (PRM) program: A real-world data platform of cancer drugs use to improve and personalize drug pricing and reimbursement in France.

open access: yesPLoS ONE, 2022
ObjectiveThis article describes the Personalized Reimbursement Model (PRM) program methodology, limitations, achievement and perspectives in using real-world data of cancer drugs use to improve and personalize drug pricing and reimbursement in France ...
Pierre-Alexandre Squara   +9 more
doaj   +1 more source

Sulfur-containing radicals: From EPR spectroscopic studies to synthetic methodology. [PDF]

open access: yes, 2002
A variety of novel homochiral silanethiols have been prepared and investigated as polarity-reversal catalysts for the enantioselective hydrosilylation of a prochiral alkene. The enantiomeric excesses of the products were disappointingly small. A computer
Fielding, Alistair John
core  

“Membrane‐Guided” Repair Strategy: Precision Delivery of GGT1 Degrader for Targeted Repair and Regeneration of Spinal Cord Neurons

open access: yesAdvanced Science, EarlyView.
This study confirms that GGT1 is a key driver of neuronal ferroptosis following spinal cord injury. We developed NSCm@EA, a biomimetic delivery system coated with neural stem cell membranes, for precise delivery of enocyanin to injured neurons. By combining targeted delivery with ubiquitination degradation mechanisms, this system promotes MGRN1 ...
Tao Yang   +14 more
wiley   +1 more source

Evolutionary Polynomial Regression Algorithm with Uncertain Variables: Two Case-Studies in the Field of Civil Engineering

open access: yesApplied Sciences
Data-driven approaches and calibration techniques for mathematical models, starting from observed data, are attracting more and more interest in the field of civil engineering.
Alessandra Fiore   +2 more
doaj   +1 more source

Advances in Data-Driven Analyses and Modelling Using EPR-MOGA

open access: yes, 2009
Evolutionary Polynomial Regression (EPR) is a recently developed hybrid regression method that combines the best features of conventional numerical regression techniques with the genetic programming/symbolic regression technique.
Giustolisi, O., Savic, D. A.
core   +1 more source

Quantum Nanomedicine and Quantum Biomaterials

open access: yesAdvanced Science, EarlyView.
In this perspective, we define quantum nanomedicine and quantum biomaterials as a paradigm that harnesses quantum effects in nanomedicine and biomaterials, including quantum superposition, quantum coherence, quantum tunneling, topological quantum effects, and spin polarization, to achieve either spatiotemporally precise modulation of physiological ...
Xinyue Dai   +3 more
wiley   +1 more source

H2S‐Amplified “Three‐in‐One” Antibacterial Strategy for Periodontitis Treatment Using a Photosensitive Pillararene‐Embedded COF/MOF Hybrid

open access: yesAdvanced Science, EarlyView.
The integration of ROS‐generating systems with H2S depletion strategies effectively overcomes the limitations imposed by endogenous antioxidant defenses on ROS‐based antimicrobial therapies. In this study, the Cu‐MOF is incorporated into pillararene‐embedded COF, achieving a “three‐in‐one” antimicrobial effect that markedly alleviated periodontal ...
Shuang Liang   +9 more
wiley   +1 more source

Operational intervention levels for reactor emergencies IAEA recommendations

open access: yesBrazilian Journal of Radiation Sciences, 2018
The IAEA publication EPR-NPP-OILs-2017, OPERATIONAL INTERVENTION LEVELS FOR REACTOR EMERGENCIES AND METHODOLOGY FOR THEIR DERIVATION [1], provides selected default OIL values, describing a methodology for their derivation, as well as practical tools and ...
Lais Alencar de Aguiar   +2 more
doaj   +1 more source

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