Penetration Enhancer-Free Mixed Micelles for Improving Eprinomectin Transdermal c Efficiency in Animal Parasitic Infections Therapy [PDF]
Yujuan Mao,1,* Tianjiao Hao,2,* Hongxiu Zhang,2,* Xiaofei Gu,2 Jing Wang,1 Feifei Shi,1 Xiaolan Chen,1 Liuna Guo,1 Jie Gao,1 Yan Shen,2 JinLin Zhang,3 Shenglan Yu4 1Jiangsu Agri-Animal Husbandry Vocational College, Taizhou, Jiangsu, 225300 ...
Mao Y +11 more
doaj +4 more sources
Comparing Short Versus Long Persistency of Anthelmintics: Impacts on Dairy Sheep Production [PDF]
Introduction: Grazing dairy ewes are often heavily challenged by parasitic infections, which represent one of the most important concerns in sheep farming due to their impacts on dairy sheep production.
Konstantinos V. Arsenopoulos +2 more
doaj +2 more sources
Assessment of clinically relevant drugs as feline P-glycoprotein substrates [PDF]
IntroductionThe drug transporter P-glycoprotein (P-gp) influences drug disposition by playing key roles in limiting brain penetration and enhancing biliary excretion of substrate drugs. Guidance documents from U.S.
Katrina L. Mealey, Neal S. Burke
doaj +2 more sources
Effects of vitamins A and E on eprinomectin transport in Caco-2 cells [PDF]
Eprinomectin (EPR) is a macrocyclic lactone antiparasitic widely used in veterinary medicine. Although the off-label oral use of the pour-on formulation of EPR is known to be effective and practical, data regarding its interactions with foods or vitamin ...
Y Gunes +6 more
doaj +2 more sources
Anthelmintic Resistance to Pour-On Eprinomectin Against Gastrointestinal Strongyles and Effects on Production Parameters in Early-Lactating Dairy Goats [PDF]
Gastrointestinal strongyle infections are a common challenge in dairy goat farming, potentially impacting animal health and milk production. We, therefore, conducted a study to evaluate the efficacy of pour-on eprinomectin (EPM) in early-lactating dairy ...
Luisa Rambozzi +8 more
doaj +2 more sources
Prevalence of Lungworm Infections in Hedgehogs (Erinaceus roumanicus) in Greece and a Novel Therapeutic Approach for Treatment [PDF]
The most common causes of respiratory diseases in wild hedgehogs are the lungworms Crenosoma striatum and Capillaria aerophila, which can lead to life-threatening pneumonia. The aim of the current study was (A) to assess the prevalence of common lungworm
Grigorios Markakis +5 more
doaj +2 more sources
Automated larval motility assays reveal links between eprinomectin treatment failure and drug resistance in Haemonchus contortus [PDF]
Small ruminants are frequently infected with gastrointestinal nematode parasites (GIN) such as the highly pathogenic Haemonchus contortus, which severely impact animal health, welfare and production performance.
Julie Petermann +11 more
doaj +2 more sources
In vivo efficacy of macrocyclic lactones on goat farms – pour-on vs injectable application [PDF]
Pour-on eprinomectin (EPN) is the only anthelmintic currently available that is approved for use in lactating goats with a zero-day milk withdrawal period.
Babják Michal +3 more
doaj +2 more sources
Inherent P-glycoprotein deficiency and macrocyclic lactone toxicity in an Australian Maine Coon cat homozygous for 1930_1931del TC [PDF]
Case summary A 9-month-old castrated male Maine Coon cat developed tongue protrusion, mydriasis, generalised weakness and ataxia after routine application, as per label guidelines, of NexGard Spectra (Boehringer Ingelheim; active ingredients praziquantel
Madeleine L Roberts
doaj +2 more sources
Evaluation of Extended-Release Eprinomectin Injectable and Doramectin Injectable with the Inclusion of Refugia on Performance Outcomes and Fecal Parameters in Stocker Cattle [PDF]
Evaluating different tactics to mitigate the effects of gastrointestinal nematode infection in growing stocker cattle is essential to better understand opportunities to optimize cattle health and performance.
Daniel B. Cummings +3 more
doaj +2 more sources

