Results 141 to 150 of about 1,407 (179)

Eprinomectin: A Novel Avermectin for Use as a Topical Endectocide for Cattle

International Journal for Parasitology, 1996
Eprinomectin (MK-397 or 4"-epi-acetylamino-4"-deoxy-avermectin B1) is a novel avermectin selected for development as a topical endectocide for all cattle, including lactating dairy cows. Herein, we show its anthelmintic, insecticidal and miticidal activity.
C H Eary, W C Campbell, J R Egerton
exaly   +3 more sources

Pharmacokinetics of Eprinomectin in Plasma and Milk Following Subcutaneous Administration to Lactating Dairy Cattle

Veterinary Research Communications, 2006
Eprinomectin is only available as a topically applied anthelmintic for dairy cattle. To determine whether eprinomectin can be applied as an injectable formulation in dairy cattle, a novel injectable formulation was developed and was subcutaneously ...
Baoliang, Pan, Ming, Wang, Zhende, Pan, Lifschitz, Adrian Luis, Yuwan, Wang, P. Baoliang, W. Yuwan, P. Zhende, A. L. Lifschitz, W. Ming   +9 more
exaly   +2 more sources

Characterization of Eprinomectin N-Deacetylase in Rats

Drug Metabolism and Disposition, 1999
The enzyme system responsible for the N-deacetylation of eprinomectin in rats was characterized. Tissue and subcellular studies showed that the hydrolysis activity was localized mainly in liver microsomes. Apparent KM and Vmax values calculated from Lineweaver-Burk plots were 53 microM and 0.81 nmol/mg/min for male rats and 70 microM and 4.99 nmol/mg ...
Z, Zeng, N W, Andrew
openaire   +2 more sources

Injectable eprinomectin for cattle: Tick efficacy and pharmacokinetics

Journal of Veterinary Pharmacology and Therapeutics, 2020
AbstractThe aims of the present study were to evaluate the pharmacokinetic profile and efficacy of eprinomectin (EPM) against Rhipicephalus microplus in cattle of a new injectable form of EPM (Voss Performa®). The product was administered subcutaneously at a dose of 200 μg EPM/kg, in a single dose. The efficacy of EPM against R. microplus in cattle was
Cristiano Grisi do Nascimento, Gabrielle Bragaglia, Sandra Barioni Toma, Viviane de Souza Magalhães, Yara Peluso Cid, Fabio Barbour Scott   +5 more
openaire   +2 more sources

Efficacy of eprinomectin against Hypoderma spp in cattle

American Journal of Veterinary Research, 1998
SUMMARY Objective To determine the efficacy of a topical formulation of eprinomectin against natural infestations of first (L1)-stage, and second and third (L2/L3)-stage larvae of Hypoderma spp. Animals 140 approximately 6- to 18-month-old cattle of various breeds. Procedure Cattle, selected from herds with high prevalence of Hypoderma infestation,
J E, Holste, D D, Colwell, R, Kumar, J E, Lloyd, N P, Pinkall, M A, Sierra, J W, Waggoner, W K, Langholff, R A, Barrick, J S, Eagleson   +9 more
openaire   +2 more sources

Preparation of Eprinomectin Nanoemulsions and Determination of Their Pharmacokinetics and Pharmacodynamics in Dairy Cows

Journal of Biomedical Nanotechnology, 2022
This study aimed to develop an anthelmintic that leaves no residues and is safe and efficient for use in cows. We constructed classical pseudoternary phase diagrams using experimental animal data to optimize and characterize the eprinomectin nanoemulsion formulas.
Qiu, Gang, Rui, Yapei
openaire   +2 more sources

Efficacy of eprinomectin against mange mites in cattle

American Journal of Veterinary Research, 1997
SUMMARY Objective To determine whether eprinomectin was effective against mange caused by Chorioptes bovis and Sarcoptes bovis in cattle. Animals 80 cows naturally infested with C bovis and 30 cattle experimentally infested with S bovis. Procedure 6 trials were performed to determine efficacy against C bovis, and 2 trials were performed to ...
D, Barth, J A, Hair, B N, Kunkle, W K, Langholff, M, Löwenstein, S, Rehbein, L L, Smith, J S, Eagleson, E, Kutzer   +8 more
openaire   +2 more sources

Chorioptic mange in dairy cattle: treatment with eprinomectin pour-on

Parasitology Research, 2005
A randomized block design study was conducted to confirm the efficacy of topical eprinomectin against naturally acquired Chorioptes bovis mite infestations. Twelve adult Simmentaler Fleckvieh cattle were formed into six replicates of two animals based on pretreatment mite counts.
Steffen, Rehbein, Renate, Winter, Martin, Visser, Ana E, Maciel, Sara E, Marley   +4 more
openaire   +2 more sources

Analytical procedure for the determination of eprinomectin in soil and cattle faeces

Journal of Chromatography B, 2010
A new analytical HPLC-fluorescence method was developed for the quantitative determination of eprinomectin (EPM) in soil and cattle faeces. EPM was extracted with acetone and acetonitrile from soil and cattle faeces, respectively. Solid phase extraction and derivatization reaction with N-methylimidazole in the presence of trifluoroacetic anhydride and ...
V D, Litskas, G C, Batzias, X N, Karamanlis, A P, Kamarianos   +3 more
openaire   +2 more sources

Effects of flumethrin and eprinomectin in naturally infected mice with Myocoptes musculinus

Experimental Parasitology, 2022
Mite infestations can occur in laboratory mice and cause an undesirable immune system response and adversely affect study results. Myocoptes musculinus is a mite species that can occasionally parasitized in laboratory-housed and breeding mice. In this study, the efficacy of flumethrin and eprinomectin were compared in 30 male Balb/c mice naturally ...
Serdar Aktas, Serkan Bakırcı, Huseyin Bilgin Bilgic, Onur Kose   +3 more
openaire   +2 more sources