Results 131 to 140 of about 1,675 (190)
Navigating polycythemia vera and factor X deficiency on cardiopulmonary bypass for coronary artery bypass grafting: a case report. [PDF]
Cornibe JL, Katz AH.
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Paraneoplastic Hyperfibrinolysis in Oesophageal Adenocarcinoma: A Case Report. [PDF]
Zhou Y, Gelson W, Brais R, Besser M.
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Immune Thrombocytopenia and Type 1 von Willebrand Disease in a Patient With a Femoral Fracture: A Case Report. [PDF]
Ferreira A, Roberto A.
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Enhanced recovery after surgery: overarching themes of the ERAS® Society Guidelines & Consensus Statements for Adult Specialty Surgery. [PDF]
Grant MC, Engelman DT.
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Epsilon-Aminocaproic Acid (EACA)
Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. It is the only potent antifibrinolytic agent which is commercially available in the United States. Effective blood levels of the drug are readily obtainable with either oral or intravenous administration, with very high levels of the drug being found in the ...
J D, Griffin, L, Ellman
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Reduction of Postprostatectomy Bleeding by Epsilon-Aminocaproic Acid
New England Journal of Medicine, 1962EPSILON-aminocaproic acid (EACA) is a potent inhibitor of plasminogen activation in relatively low concentrations (5 × 10–4M) and of plasmin at considerably higher concentrations (1 × 10–2M).1 , 2 This drug, first described by Japanese investigators, has the structural formula: Clinical studies have indicated that it is effective in hemorrhagic ...
Theodore H Spaet +2 more
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Epsilon Aminocaproic Acid — A Dangerous Weapon
Of the body's defenses against injury, the proteolytic activity of plasmin, an enzyme that can evolve in plasma from an inert precursor, plasminogen, is most intriguing. Clinical attention has been centered upon the digestion of fibrin by plasmin, but this enzyme also digests other clotting factors, converts the first component of complement to its ...
Oscar D. Ratnoff
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Rhabdomyolysis During Treatment With Epsilon-Aminocaproic Acid
Severe rhabdomyolysis and acute renal failure occurred in a patient receiving epsilon-aminocaproic acid. The lack of evidence of vascular involvement in the muscle biopsy specimen suggests that epsilon-aminocaproic acid may have direct myotoxicity. This drug may produce a spectrum of muscle disease from mild myopathy to life-threatening rhabdomyolysis.
C W, Britt +3 more
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