Results 161 to 170 of about 11,106 (236)
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An Examination of Aneurysm Rerupture Rates with Epsilon Aminocaproic Acid

Neurocritical Care, 2013
Epsilon aminocaproic acid (EACA) has been used in the past to prevent cerebral aneurysm rerupture. Recent studies have indicated that short-term treatment with EACA can lower rebleeding rates without significantly increasing ischemic or thrombotic complications or permanent shunt rates. The goal of this study is to determine the efficacy of EACA in the
A. Schuette   +6 more
semanticscholar   +4 more sources

Comparison of effectiveness and safety of epsilon-aminocaproic acid and tranexamic acid in adult patients undergoing cardiac surgery

Journal of Medical Society, 2022
Objective: The objective of the study is to evaluate the effectiveness and safety of epsilon-aminocaproic acid (EACA) and tranexamic acid (TXA) in reducing bleeding, re-exploration, and blood transfusion in patients who underwent a cardiac surgical ...
L. Singh   +4 more
semanticscholar   +1 more source

Epsilon-Aminocaproic Acid (EACA)

Seminars in Thrombosis and Hemostasis, 2008
Epsilon-aminocaproic acid (EACA) is a synthetic inhibitor of the plasmin-plasminogen system. It is the only potent antifibrinolytic agent which is commercially available in the United States. Effective blood levels of the drug are readily obtainable with either oral or intravenous administration, with very high levels of the drug being found in the ...
James D. Griffin, Leonard Ellman
openaire   +3 more sources

Determination of Epsilon Aminocaproic Acid Based on Charge Transfer Complexation with p-Nitrophenlol by Spectrophotometry

, 2020
Spectrophotometry was investigated for the determination of epsilon aminocaproic acid (EACA) with p-nitrophenol (PNP). The method was based on Charge Transfer (CT) complexation of this drug as n-electron donor with π-acceptor PNP.
S. Li, Fang Tian
semanticscholar   +1 more source

Rhabdomyolysis Induced by Epsilon-Aminocaproic Acid

Annals of Pharmacotherapy, 1997
OBJECTIVE: To report a case of rhabdomyolysis associated with epsilon-aminocaproic acid (epsilon-ACA). CASE SUMMARY: A 33-year-old female patient with chronic granulocytic leukemia was treated with epsilon-ACA for approximately 3.5 months for thrombocytopenic bleeding. The initial dosage was 4 g po q6h.
Morel Rubinger, Beverly D Seymour
openaire   +3 more sources

Thrombosis with Epsilon Aminocaproic Acid Therapy

American Journal of Clinical Pathology, 1971
A patient with postoperative bleeding was treated with epsilon aminocaproic acid (EACA). Subsequent coagulation studies supported the diagnosis of intravascular coagulation and the patient subsequently developed renal failure due to glomerular thromboses.
Harvey R. Gralnick, Philip Greipp
openaire   +3 more sources

Tranexamic acid or epsilon-aminocaproic acid in total joint arthroplasty? A randomized controlled trial.

The Bone & Joint Journal, 2019
AIMS Antifibrinolytic agents, including tranexamic acid (TXA) and epsilon-aminocaproic acid (EACA), have been shown to be safe and effective for decreasing perioperative blood loss and transfusion following total hip arthroplasty (THA) and total knee ...
Kendall E Bradley   +8 more
semanticscholar   +1 more source

Effect of probenecid on the kinetics of epsilon-aminocaproic acid

Clinical Pharmacology and Therapeutics, 1980
Healthy male subjects received, 1 wk apart, single oral doses of epsilon-aminocaproic acid (EACA) 100 mg/kg alone, EACA within probenecid (0.5 gm), or EACA 2 hr after 2.0 gm probenecid. Probenecid (2.0 gm) reduced the 8-hr urinary clearance and recovery of EACA by 50% without affecting plasma kinetics.
Kerry L Katlic   +3 more
openaire   +3 more sources

Epsilon-Aminocaproic acid therapy in ulcerative colitis

The American Journal of Digestive Diseases, 1973
A double-blind cross-over trial of the effect of Epsilon-Aminocaproic acid (EACA) versus placebo on gastrointestinal blood loss in 13 patients with proctocolitis showed no statistically significant reduction in blood loss recorded by the disappearance rate, as detected by whole-body monitoring of parenterally administered59Fe.
K. Boddy   +5 more
openaire   +3 more sources

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