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Myopathy induced by epsilon-aminocaproic acid [PDF]
Journal of Neurosurgery, 1982 ✓ The authors present a case of proximal myopathy secondary to epsilon-aminocaproic acid (EACA) administration. This well recognized entity does not occur immediately after institution of therapy, but follows a delay of several days and a cumulative dose.
Sean Mullan +2 more
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Paediatric anaesthesia, 2019
Open cranial vault reconstruction is frequently performed for craniosynostosis. These procedures often involve high volume blood loss that requires blood transfusion.
Thanh T Nguyen +5 more
semanticscholar +1 more source
Open cranial vault reconstruction is frequently performed for craniosynostosis. These procedures often involve high volume blood loss that requires blood transfusion.
Thanh T Nguyen +5 more
semanticscholar +1 more source
Epsilon-Aminocaproic Acid for Synovectomy in Haemophilic Patients
Acta Haematologica, 1972The study of coagulation and fibrinolysis in synovectomised haemophilic patients, treated by a new haemostatic combined therapy, is reported. This treatment is based on a combination of replacement therapy (fresh frozen plasma and/or cryoprecipitates) and e-aminocaproic acid; the replacement therapy is continued for only 6 days, beginning on the day of
Gamba G +5 more
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HAEMORRHAGIC CYSTITIS TREATED WITH EPSILON–AMINOCAPROIC ACID
Medical Journal of Australia, 1980A life-threatening haemorrhagic cystitis, which occurred in a patient with metastatic prostatic carcinoma, was controlled with epsilon-aminocaproic acid (EACA) after conventional approaches to treatment failed. EACA administration was both systemic and intravesical, and control of bleeding occurred within 24 hours after initiation of treatment.
R. S. Aroney, John A. Levi, D. N. Dalley
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Rhabdomyolysis During Treatment With Epsilon-Aminocaproic Acid
Archives of Neurology, 1980Severe rhabdomyolysis and acute renal failure occurred in a patient receiving epsilon-aminocaproic acid. The lack of evidence of vascular involvement in the muscle biopsy specimen suggests that epsilon-aminocaproic acid may have direct myotoxicity. This drug may produce a spectrum of muscle disease from mild myopathy to life-threatening rhabdomyolysis.
Randall R. Light +3 more
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Epsilon Aminocaproic Acid — A Dangerous Weapon
New England Journal of Medicine, 1969Of the body's defenses against injury, the proteolytic activity of plasmin, an enzyme that can evolve in plasma from an inert precursor, plasminogen, is most intriguing. Clinical attention has been centered upon the digestion of fibrin by plasmin, but this enzyme also digests other clotting factors, converts the first component of complement to its ...
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Epsilon-Aminocaproic Acid Myopathy
European Neurology, 1982A case of acute necrotic myopathy due to epsilon-aminocaproic acid (EACA) is described and compared with similar cases in the literature. This myopathy has only been noted after prolonged administration of the drug. The pathogenesis of this necrotic myopathy remains unclear, but our finds did not support a muscular vasculitis or an autoimmune reaction.
J.A.L. Vanneste, G.K. van Wijngaarden
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Efficacy of Epsilon Aminocaproic Acid [EACA] in Epistaxis
Indian Journal of Otolaryngology and Head and Neck Surgery, 1995The present study has confirmed that EACA may be tried topically upon mild to moderate patients of Epistaxis at random without any possibility of any major complication.
Major A. K. Mehta, P. C. Chamyal
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Epsilon-Aminocaproic Acid in Treatment of Acute Pancreatitis
Scandinavian Journal of Gastroenterology, 1971During the years 1964-1966, 47 patients with acute pancreatitis were treated with epsilon-aminocaproic acid. All the patients recovered. Another group, consisting of 41 patients, was during the same period treated with Trasylol. Two of these patients died. One had massive pulmonary embolism and pancreatic necrosis. The other had pancreatic necrosis and
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Effects of Epsilon Aminocaproic Acid on Primary Hemostasis
Pathophysiology of Haemostasis and Thrombosis, 1991These studies examined the effect of an oral dose of ε-aminocaproic acid (EACA) on primary hemostasis. Bleeding time tests (with and without the use of a blood pressure cuff) were measured before and 2 h following EACA in 56 patients with mild bleeding disorders and/or thrombocytopenia.
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