Results 181 to 190 of about 26,198 (210)
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Journal of Biomolecular Structure and Dynamics, 2013
Although the proposed mechanisms are reasonable, there are still many questions about the 5-enolpyruvyl shikimate-3-phosphate (EPSP) synthase mechanism that are difficult to answer by experimental means alone. EPSP synthase is a key enzyme in the shikimic acid pathway, which is found only in plants and some micro-organisms and is also molecular target ...
Melissa Soares, Caetano +3 more
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Although the proposed mechanisms are reasonable, there are still many questions about the 5-enolpyruvyl shikimate-3-phosphate (EPSP) synthase mechanism that are difficult to answer by experimental means alone. EPSP synthase is a key enzyme in the shikimic acid pathway, which is found only in plants and some micro-organisms and is also molecular target ...
Melissa Soares, Caetano +3 more
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A New Echeloned Poisson Series Processor (EPSP)
Celestial Mechanics and Dynamical Astronomy, 2001zbMATH Open Web Interface contents unavailable due to conflicting licenses.
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Neuroscience Letters, 1998
In slices kept at 33 degrees C, N-methyl-D-aspartate (NMDA) receptor- and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated field excitatory post-synaptic potentials (EPSPs) were pharmacologically isolated in CA1.
R, Nader, R, Forghani, K, Krnjević
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In slices kept at 33 degrees C, N-methyl-D-aspartate (NMDA) receptor- and (+/-)-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA) receptor-mediated field excitatory post-synaptic potentials (EPSPs) were pharmacologically isolated in CA1.
R, Nader, R, Forghani, K, Krnjević
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Journal of Neurophysiology, 1996
1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied for 20 min consistently induced a
N A, Breakwell, M J, Rowan, R, Anwyl
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1. We reexamined the important areas of conflict in (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid [(1S,3R)-ACPD]-induced potentiation of the field excitatory postsynaptic potential (EPSP) and, for the first time, investigated the role of mGluRs in EPSP-spike (E-S) coupling. 2. (1S,3R)-ACPD (10 microM) bath applied for 20 min consistently induced a
N A, Breakwell, M J, Rowan, R, Anwyl
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Journal of the American Chemical Society, 1992
A number of analogues of the intermediate and product of the enzyme EPSP synthase are described. Inert analogues that show high affinity for the enzyme from Petunia hybrida are produced by replacing the labile ketal phosphate moiety of this intermediate with a phosphonate or by stabilizing the ketal phosphate against ionization through introduction of ...
David G. Alberg +4 more
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A number of analogues of the intermediate and product of the enzyme EPSP synthase are described. Inert analogues that show high affinity for the enzyme from Petunia hybrida are produced by replacing the labile ketal phosphate moiety of this intermediate with a phosphonate or by stabilizing the ketal phosphate against ionization through introduction of ...
David G. Alberg +4 more
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Ia reflexes and EPSPs in human soleus motor neurones
Experimental Brain Research, 1989The reflex responses of single motor units in the soleus muscle to electrical stimulation of the tibial nerve were recorded in human volunteers. A feature of the experiments was the stimulation paradigm used. In order to control the peri-stimulus firing rate, a computer triggered the stimulus isolator only when 2 interspike intervals of specified ...
T S, Miles, K S, Türker, T H, Le
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Nonlinear temporal summation of EPSP in mollusk neurons
Neurophysiology, 1989Temporal summation of monosynaptic EPSPs produced by paired afferent stimuli was studied in the experiments on identified neurons of mollusc Planorbis corneus. Nonlinear properties of the summation were shown; there were three types of the summation: facilitation, depression and mixed type.
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Altered desensitization produces enhancement of EPSPs in neocortical neurons
Journal of Neurophysiology, 19941. Neocortical brain slices were prepared from rats (35–50 days of age) and maintained in vitro. Intracellular recordings were obtained from neurons in cortical layers II/III. The effect of bath application of cyclothiazide (CYZ), a potent blocker of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor desensitization, on evoked ...
M R, Pelletier, J J, Hablitz
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Structural bioinformatics study of EPSP synthase from Mycobacterium tuberculosis
Biochemical and Biophysical Research Communications, 2003The shikimate pathway is an attractive target for herbicides and antimicrobial agent development because it is essential in algae, higher plants, bacteria, and fungi, but absent from mammals. Homologues to enzymes in the shikimate pathway have been identified in the genome sequence of Mycobacterium tuberculosis.
Pereira, J. H. +7 more
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Atropine enhances nicotinic cholinergic EPSPs in rat neostriatal slices
Brain Research, 1982Abstract Atropine enhances and muscarinic agonists reduce the amplitudes of EPSPs evoked by intrastriatal stimulation in rat neostriatal slices. The mechanism of action suggested is presynaptic muscarinic modulation of an EPSP which is caused by cholinergic activation of nicotinic receptors on the cholinoceptive neuron.
U, Misgeld, M H, Weiler, D K, Cheong
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