Results 81 to 90 of about 205,978 (334)

Immune-checkpoint expression in Epstein-Barr virus positive and negative plasmablastic lymphoma: a clinical and pathological study in 82 patients

Haematologica, 2016
Plasmablastic lymphoma is a rare and aggressive diffuse large B-cell lymphoma commonly associated with Epstein-Barr virus co-infection that most often occurs in the context of human immunodeficiency virus infection.
Camille Laurent, Bettina Fabiani, Catherine Do, Emmanuelle Tchernonog, Guillaume Cartron, Pauline Gravelle, Nadia Amara, Sandrine Malot, Maryknoll Mawanay Palisoc, Christiane Copie-Bergman, Alexandra Traverse Glehen, Marie-Christine Copin, Pierre Brousset, Stefania Pittaluga, Elaine S. Jaffe, Paul Coppo   +15 more
doaj   +1 more source

Epstein-Barr virus latent proteins regulate expression of the anti-apoptotic cellular bfl-1 gene [PDF]

, 2005
The ubiquitous and oncogenic human herpes-virus Epstem-Barr virus (EB V) establishes a latent infection and promotes the long-term survival of the infected host cell by targeting the molecular machinery that controls cell fate decisions, including ...
Smith, Sinéad M.
core  

Atypical Clinical Course of Griscelli Syndrome Type 2 With Primarily Neurologic Presentation and Adult‐Onset in a 46‐Year‐Old Male

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Griscelli Syndrome Type 2 (GS2) is a rare autosomal recessive disorder caused by pathogenic mutations in the RAB27A gene. Typically, it is characterized by cutaneous hypopigmentation, immunodeficiency, with or without neurological abnormalities secondary to hemophagocytic lymphohistiocytosis (HLH). Without treatment, GS2 often results in fatal
Dzhoy Papingi, Michael Kutsche, Helena Lichtenfeld, Fanny Kortüm, Angela Abicht, Laura Herrmann, Theresia Herget   +6 more
wiley   +1 more source

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

Epstein‐Barr virus strain variation and cancer

Cancer Science, 2019
Epstein‐Barr virus (EBV) is a human tumor virus and is etiologically linked to various malignancies. Certain EBV‐associated diseases, such as Burkitt lymphomas and nasopharyngeal carcinomas, are endemic and exhibit biased geographic distribution ...
T. Kanda, Misako Yajima, K. Ikuta
semanticscholar   +1 more source

Latent Epstein-Barr virus infection and the germinal center reaction [PDF]

, 2007
Epstein-Barr virus (EBV) is a γ-herpes virus which preferentially infects human B lymphocytes. It is highly adapted to persist in B cells since it encodes for proteins which mimic several cellular proteins playing an important role in B cell ...
Rastelli, Julia, Rastelli, J.
core  

Humanized immune system animal models and their recent applications

Animal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli, Rudra B. Amin, A’ishah Bakayoko, Marisa Kruidenier, Sahara Aqui, Sarah J. Skuli, Terence P. Gade   +6 more
wiley   +1 more source

Atypical manifestations of Epstein–Barr virus in children: a diagnostic challenge

Jornal de Pediatria, 2016
Objective: Clarify the frequency and the pathophysiological mechanisms of the rare manifestations of Epstein–Barr virus infection. Sources: Original research studies published in English between 1985 and 2015 were selected through a computer-assisted ...
Vasileios Bolis, Christos Karadedos, Ioannis Chiotis, Nikolaos Chaliasos, Sophia Tsabouri   +4 more
doaj   +1 more source

Fibromyalgia in the Setting of Prior Epstein-Barr Virus Infection: A Case Report. [PDF]

Clin Case Rep
ABSTRACT Accurate diagnosis of fibromyalgia requires careful consideration of overlapping conditions. This case underscores the role of Epstein–Barr virus (EBV) serology in patients with persistent fatigue and pain, while illustrating the challenges of diagnosing fibromyalgia amid concurrent health problems.
Bhattessa S, Dave T, Modi P.
europepmc   +2 more sources

A global view of the oncogenic landscape in nasopharyngeal carcinoma : an integrated analysis at the genetic and expression levels [PDF]

, 2012
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit recurrent chromosome abnormalities. These genetic changes are broadly assumed to lead to changes in gene expression which are important for the pathogenesis of
Aicha Amari, Murray, Paul G, Dawson, Christopher W, Wei, Wenbin, Xiaoyi Chen (150873), Sim K. Sihota (150887), Shao, Jian-Yong, Andrew I Bell, Maloney, S.L., Nicholls, John M, Shao, J.Y., Aicha Amari (150894), Hu, C., K Dalia Derkaoui, Stephanie L Maloney, Wei, W., Arrand, J.R., Wenbin Wei (150871), Woodman, C.B., Sihota, Sim K, Murray, P.G., Ciaran B. Woodman (150878), Derkaoui, K.D., Ciaran B Woodman, Jian-Yong Shao (41845), Maloney, Stephanie L., Bell, Andrew I., Dawson, Christopher W., John M. Nicholls (150882), Derkaoui, K Dalia, Derkaoui, K. Dalia, Maloney, Stephanie L, Bell, A.I., Sihota, Sim K., Xiaoyi Chen, Lawrence S. Young (150912), Woodman, Ciaran B. J., Nicholls, J.M., Arrand, J. R. (John R.), Irène Joab (150885), Joab, Irène, Amari, Aicha, Arrand, John R, Woodman, Ciaran B, Wenbin Wei, Paul G. Murray (150907), Christopher W. Dawson (150910), Chen, X., Yao, Yunhong, Chunfang Hu, Dawson, C.W., Chunfang Hu (150868), K. Dalia Derkaoui (150892), Andrew I. Bell (150904), Chen, Xiaoyi, Young, Lawrence S., Joab, I., John R. Arrand (150915), Irène Joab, Christopher W Dawson, Nicholls, J. M. (John M.), Stephanie L. Maloney (150899), Yunhong Yao, Wei, Wenbin; id_orcid, Young, Lawrence S, Lawrence S Young, John R Arrand, John M Nicholls, Paul G Murray, Amari, A., Jian-Yong Shao, Bell, Andrew I; id_orcid, Yao, Y., Yunhong Yao (150880), Hu, Chunfang, Young, L.S., Sihota, S.K., Murray, Paul G., Sim K Sihota   +78 more
core   +1 more source