Results 101 to 110 of about 205,978 (334)

Guillain-Barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction We present a case of an unusual clinical manifestation of Guillain-Barre syndrome following a pre-existing herpes virus infection. Although there have been several reports describing the co-existence of herpes virus infection and Guillain ...
Ntziora Fotinie   +4 more
doaj   +1 more source

Clinical and Laboratory Peculiarities of Chronic Active M. Epstein – I. Barr Virus Infection Course in Patients with Allergic Diseases

open access: yes, 2018
Introduction. In case of weak or insufficient immune response, activation of chronic M. Epstein – I. Barr virus infection initiates different pathological disorders, one of which is allergy. Aim.
Zubchenko S., Chopyak V.
core   +1 more source

Mutation type‐specific transcriptomic signatures and readthrough therapy rescue in SMC1A‐related developmental and epileptic encephalopathy

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to investigate the molecular consequences of pathogenic variants in the SMC1A gene—particularly those associated with developmental and epileptic encephalopathy (DEE85)—and to evaluate the therapeutic potential of ataluren in restoring SMC1A function and mitigating disease‐related transcriptomic and genomic ...
Maddalena Di Nardo   +7 more
wiley   +1 more source

Structure-based design of small-molecule inhibitors of EBNA1 DNA binding blocks Epstein-Barr virus latent infection and tumor growth

open access: yesScience Translational Medicine, 2019
EBNA1 inhibitors developed by fragment-based drug design block EBNA1 DNA binding and EBV-dependent tumor cell growth in vivo. No holds Barr-ed for cancer treatment Persistent latent infection with Epstein-Barr virus contributes to tumorigenesis in a ...
T. Messick   +17 more
semanticscholar   +1 more source

Cervical cancer with Human Papilloma Virus and Epstein Barr Virus positive [PDF]

open access: yes, 2006
The Early-7 (E7) protein of HPV binds to the underphosphorelated form of the tumor suppressor protein – pRb and displaces the E2F transcription factor that is normally bound by pRb.
Prayitno, Adi
core  

Epstein-Barr Virus and DNA Methylation in Gastric Cancer

open access: yes, 2016
Gastric cancer (GC) is the fourth most common type of malignity and the second leading cause of cancer death worldwide. Infectious agents such as Helicobacter pylori (H.pylori) and Epstein-Barr virus (EBV) play important role in the etiology in GC.
Nursal, Ayse Feyda, Ayşe Feyda Nursal
core   +1 more source

Epstein-Barr Virus Entry [PDF]

open access: yesJournal of Virology, 2007
One of the many conundrums of herpesvirology is why a herpesvirus is so profligate in its use of four or more envelope glycoproteins for entry into a cell when other viruses can manage very well with only one or two. Profligacy does, however, have its advantages.
openaire   +2 more sources

Randomized Phase II Trial of Consolidation Pembrolizumab After Definitive Chemoradiotherapy in Locally Advanced Nasopharyngeal Carcinoma: KCSG HN19‐09, CONPELAN Study

open access: yesHead &Neck, EarlyView.
ABSTRACT Background The benefit of consolidation programmed cell death protein 1 (PD‐1) blockade after chemoradiotherapy in locoregionally advanced nasopharyngeal carcinoma (NPC) remains unclear. Methods Patients with stages II–IVB NPC were randomized (2:1) to pembrolizumab 200 mg or placebo every 3 weeks for up to 17 cycles after chemoradiotherapy ...
Sang Hoon Chun   +11 more
wiley   +1 more source

Proposed modifications and incorporation of plasma Epstein‐Barr virus DNA improve the TNM staging system for Epstein‐Barr virus‐related nasopharyngeal carcinoma

open access: yesCancer, 2018
The prognosis of patients who have Epstein‐Barr virus (EBV)‐related nasopharyngeal carcinoma (NPC) in which the tumor tissues harbor EBV have a better prognosis than those without EBV‐related NPC.
R. Guo   +12 more
semanticscholar   +1 more source

Structural, biochemical and biophysical characterisation of human transcription factor RBP-Jκ [PDF]

open access: yes, 2006
RBP-Jκ serves as interaction partner for both cellular and viral proteins. The protein mediates cellular and Epstein-Barr viral signal transduction, which in both cases results in dedifferentiation or immortalization of the cell.
Henning, Karen
core  

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