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Epstein-Barr Virus and Astrocytoma
Critical Reviews™ in Oncogenesis, 2019Epstein-Barr virus (EBV) is an established pathogen linked to a wide range of lymphoproliferative disorders and solid tumors. Astrocytoma is one of the most frequent brain tumors in children, adolescents, and young adults. Astrocyte proliferation usually occurs after brain tissue aggression, which may be of different types, including viral infection ...
Freixo, Cristiana +2 more
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The Epstein-Barr virus in autoimmunity
Springer Seminars in Immunopathology, 1995EBV, which is one of the viruses that most of us live with throughout most of our lifetimes, is capable of inducing autoantibodies reactive with a variety of normal tissue proteins. Because of this, the virus remains a constant threat for autoimmunization during our lifetimes, and this threat is in fact realized in several autoimmune diseases.
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Epstein-barr virus in multiple sclerosis
Current Neurology and Neuroscience Reports, 2009Recent seroepidemiologic and pathologic evidence suggests that prior infection with Epstein-Barr virus (EBV) may be necessary for the development of multiple sclerosis (MS). EBV infects more than 90% of all humans, most of whom remain healthy. In contrast, 99% of MS patients have evidence of prior infection with EBV.
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Epstein-Barr Virus and Autoimmunity
1996Epstein-Barr virus (EBV) is a ubiquitous member of the human herpesvirus group. The virus is the agent of infectious mononucleosis (IM) and shows the peculiar capability of immortalizing human B lymphocytes in vivo and in vitro; EBV is also associated with the development of African Burkitt’s lymphoma (BL), undifferentiated nasopharyngeal carcinoma ...
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Epstein‐Barr virus and gastric carcinoma
Pathology International, 2010Epstein‐Barr virus (EBV) has been accepted as an infective agent causing gastric carcinoma (GC). Epstein‐Barr virus‐associated GC, comprising nearly 10% of all cases of GC, is the monoclonal growth of EBV‐infected epithelial cells, which express several EBV‐latent genes (latency I program).
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Epstein–Barr virus-associated lymphomas
Expert Review of Anti-infective Therapy, 2006Following Epstein and colleagues' ground-breaking discovery of Epstein-Barr virus by electron microscopy of Burkitt's lymphoma cell lines, there came the observation that Epstein-Barr virus induces immortalization of B cells in vitro. Thus, initial hopes were of a virus confined to equatorial Africa with a causal link to a particular subtype of ...
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Heterogeneity of Epstein-Barr virus
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 1979H, zur Hausen, K O, Fresen
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Epstein-Barr Virus EBV and lymphomagenesis
Frontiers in Bioscience, 2002Epstein Barr virus (EBV) is a gamma herpesvirus that is associated with several specific lymphoid malignancies, some of which occur more frequently in immunocompromised individuals. EBV infection is almost ubiquitous in healthy adults, so establishing a causal role in lymphomagenesis has been difficult.
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