Results 111 to 120 of about 1,388,067 (303)

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Epstein-Barr virus and acute retinal necrosis in a 5-year-old immunocompetent child

, 2008
Roberto Gallego-Pinazo1,2, Miguel Harto1, Jose J Garcia-Medina2,3, Inmaculada Serra1, Enrique España1, Maria D Pinazo-Duran2,41Ophthalmology Department, University Hospital, La Fe, Valencia, Spain; 2Ophthalmology Research Unit &ldquo ...
Jose J Garcia-Medina, Miguel Harto, Maria D Pinazo-Duran, Inmaculada Serra, Roberto Gallego-Pinazo, Enrique España   +5 more
core  

DNA Methylation Pattern of Early Genes of Epstein Barr Virus Associated with Gastric Carcinoma in Group of Iraqi Patients

, 2019
DNA methylation is one of the epigenetic changes that may affect cell functions, which associated with several steps of cancer progression. Gastric carcinoma is endemic in Iraq with highly association of Epstein Barr Virus infections. Epigenetic changes
Hiba Sabah Jasim
core   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia, Binquan Chu, Fengjun Chen, Xiangyu Zhu, Chen Hang, Xiaoling Yu, Jinpiao Lin   +6 more
wiley   +1 more source

Epstein Barr Virus

, 2010
The Epstein-Barr virus is a member of the herpes family, and is one of the most commonly found viruses in humans. Many people become infected during childhood, but the virus remains dormant within the throat and blood cells throughout an individual’s ...
Lindsey Brake (7916741)
core   +3 more sources

Shared genetic and molecular architecture between neurodevelopmental disorders and type 1 diabetes

Journal of Intelligent Medicine, EarlyView.
Abstract Epidemiological and clinical studies have suggested possible associations between type 1 diabetes (T1D) and neurodevelopmental disorders (NDDs), but these relationships remain inconsistent across disorders and populations. To clarify whether such mixed findings, we investigated the genetic architecture linking T1D with autism spectrum disorder
Jingxuan Zhang, Zhentao Zhou, Lirong Zhu, Wei Liu   +3 more
wiley   +1 more source

Adjuvant selection and optimization in the design of an epstein–barr virus–based multi-epitope vaccine against Burkitt lymphoma [PDF]

Jesika Trimurti, Sari Eka Pratiwi, Syarifah Nurul Yanti Rizki Syahab Asseggaf, Ysrafil Ysrafil   +3 more
openalex   +2 more sources

Analysis of the presence of Epstein-Barr virus in Hodgkin\'s lymphoma in Iranian children by EBER in situ hybridization

فصلنامه دانشگاه علوم پزشکی جهرم, 2014
Background & Objectives: Epstein-Barr virus (EBV) is a tumorigenic herpes virus and belong to DNA viruses that infects and persists in B lymphocytes in the majority of humans and also is associated with a portion of cases of Hodgkin lymphoma (HL).
leila mozafari, sohrab najafipour, mohammad- hassan meshkibaf, ali moravej   +3 more
doaj  

Suspected fibrosing cholestatic hepatitis in an immunocompetent child with hepatitis C: Case report

JPGN Reports, EarlyView.
Abstract A 12‐year‐old boy presented to our center with elevated aminotransferases, jaundice, right upper quadrant tenderness, and hepatomegaly. Evaluation revealed a highly elevated blood hepatitis C virus (HCV) ribonucleic acid (RNA) level, and liver biopsy showed canalicular and intrahepatic cholestasis, feathery degeneration of hepatocytes, and ...
Sara Bohon, Regino Gonzalez‐Peralta, Robert J. Fontana, Richard Cordle, Robin LeGallo, Frank DiPaola   +5 more
wiley   +1 more source

Linkages of the Epstein-Barr Virus in Developing Nations

, 2020
This project aims to examine and analyze the effects of Epstein-Barr Virus in developing ...
Peter Garcia
core