Results 91 to 100 of about 1,980,096 (243)

Epstein-Barr virus-associated lymphomas

, 2004
Following Epstein and colleagues' ground-breaking discovery of Epstein-Barr virus by electron microscopy of Burkitt's lymphoma cell lines, there came the observation that Epstein-Barr virus induces immortalization of B cells in vitro. Thus, initial hopes
D Brooke Johnson, Johnson, Devin Brooke, Cadeddu, Jeffrey A., Jeffrey A Cadeddu, Gandhi, M. K.   +4 more
core   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

iNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu, Farah Nazir, Ying Zhou, Yuhua Shang, Hongliang He, Tengchuan Jin   +5 more
wiley   +1 more source

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

Journal of Medical Case Reports, 2012
Introduction Post-infectious cerebellitis is an acute form of inflammatory encephalitis mainly limited to the cerebellum. It is commonly found in children, especially after viral infections such as Epstein-Barr virus.
Karunarathne Suneth, Udayakumara Yapa, Fernando Harshini   +2 more
doaj   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

iNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu, Arnaud John Kombe Kombe, Tengchuan Jin   +2 more
wiley   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

Interdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li, Han Li, Bojie Chen, Ling Jiang, Keyu Long, Jiaqi Lang, Xingxiang Pu, Erhu Xiong   +7 more
wiley   +1 more source

Unique association of COVID-19 with increased risk of aplastic anemia among various viruses: insights from a two-sample Mendelian randomization study

Journal of Translational Medicine
Background Aplastic anemia (AA) is a bone marrow failure syndrome characterized by impaired hematopoiesis in all cell lineages, leading to pancytopenia and hypocellular bone marrow.
Jixuan Zou, Yi Chen, Mingjing Wang, Weiyi Liu, Xiaomei Hu   +4 more
doaj   +1 more source

Discrepant Urinary Findings Between Dipstick Protein and Sulfosalicylic Acid Test in a Patient With Hyaline Casts: A Case Report

Journal of Clinical Laboratory Analysis, EarlyView.
In this post‐transplant patient, increased hyaline casts with negative dipstick protein but positive SSA testing occurred during evolving acute kidney injury and resolved with renal recovery. This discordant urinalysis pattern may warrant confirmatory protein testing and correlation with serial renal function in patients at high risk of AKI.
Yifei Jia, Binquan Chu, Fengjun Chen, Xiangyu Zhu, Chen Hang, Xiaoling Yu, Jinpiao Lin   +6 more
wiley   +1 more source

MRI‐Derived Lymph Node Characteristics for Risk Stratification of Distant Metastasis in Locoregionally Advanced Nasopharyngeal Carcinoma

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background MRI‐derived nodal features may improve prognostication beyond TNM staging, but distant‐metastasis risk models remain limited. Purpose To develop and internally validate an MRI model for distant metastasis prediction in locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). Study Type Retrospective.
Jing Wang, Yuxing Yu, Honghong Zhang, Haosheng Zhang, Jianxian Chen, Jiajia Zheng, Qisi Zhang, Hengyu Guo, Lanxin Lin, Yubin Hu, Sufang Qiu   +10 more
wiley   +1 more source

An Unusual Case of Atypical Lymphocytosis

Sultan Qaboos University Medical Journal, 2008
Atypical lymphocytosis due to infections is classically seen in viral and chronic bacterial infections. A four year old boy with acute streptococcal infection presented at Al-Nahdha Hospital, Muscat, Oman, with follicular tonsillitis and bilateral ...
Suresh Venugopal, Jessy George, Salima S Al-Harthy   +2 more
doaj  

Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children

BMC Research Notes, 2012
Background Infectious mononucleosis (IM) or Mononucleosis syndrome is caused by an acute infection of Epstein-Barr virus. In Latin American countries, there are little information pertaining to the clinical manifestations and complications of this ...
González Saldaña Napoleón, Monroy Colín Victor, Piña Ruiz Georgina, Juárez Olguín Hugo   +3 more
doaj   +1 more source