Results 91 to 100 of about 1,925,886 (292)

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Microbiological Diagnosis of Infection by the Epstein-Barr Virus: Pathogenic Basis [PDF]

open access: yes, 2006
This study is a review of current knowledge concerning the pathogeny of infection by the Epstein-Barr virus. An analysis is made of the biological events that take place in primary infection, persistent chronic infection, oncogenic transformation ...
Soto Pino, María José   +3 more
core   +1 more source

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

open access: yesJournal of Medical Case Reports, 2012
Introduction Post-infectious cerebellitis is an acute form of inflammatory encephalitis mainly limited to the cerebellum. It is commonly found in children, especially after viral infections such as Epstein-Barr virus.
Karunarathne Suneth   +2 more
doaj   +1 more source

Cervical cancer with Human Papilloma Virus and Epstein Barr Virus positive [PDF]

open access: yes, 2006
The Early-7 (E7) protein of HPV binds to the underphosphorelated form of the tumor suppressor protein – pRb and displaces the E2F transcription factor that is normally bound by pRb.
Prayitno, Adi
core  

Systemic candidiasis with acute Epstein-Barr virus infection

open access: yes, 1997
Systemic Candida infections are usually encountered as opportunistic infections in a setting of immunologic depression. Sepsis or arthritis due to Candida is not expected in healthy people.

core   +1 more source

The T‐Cell Response Mechanism in Human Papillomavirus‐Associated Cervical Cancer and New Strategies for Immunotherapy

open access: yesiNew Medicine, EarlyView.
ABSTRACT Human papillomavirus (HPV) is a double‐stranded DNA virus that infects human skin and mucosal tissues exclusively. The German scientist Harald zur Hausen was awarded the 2008 Nobel Prize in Physiology or Medicine for his discovery of the link between HPV infection and cervical cancer.
Fang Zhu   +5 more
wiley   +1 more source

A Tripartite Model for EBV‐Driven Multiple Sclerosis: B Cell Survival, Altered Self‐Presentation, and HLA‐DR15‐Restricted T Cell Cross‐Reactivity

open access: yesiNew Medicine, EarlyView.
ABSTRACT This commentary integrates findings from three recent Cell reports to establish a unified mechanistic model of multiple sclerosis (MS) driven by the interplay between Epstein‐Barr virus (EBV) and the HLA‐DR15 genotype. EBV promotes CNS autoimmunity through three distinct but intersecting mechanisms.
Fang Zhu   +2 more
wiley   +1 more source

Unique association of COVID-19 with increased risk of aplastic anemia among various viruses: insights from a two-sample Mendelian randomization study

open access: yesJournal of Translational Medicine
Background Aplastic anemia (AA) is a bone marrow failure syndrome characterized by impaired hematopoiesis in all cell lineages, leading to pancytopenia and hypocellular bone marrow.
Jixuan Zou   +4 more
doaj   +1 more source

Enhanced CRISPR‐cas systems for genome editing and molecular diagnostics

open access: yesInterdisciplinary Medicine, EarlyView.
This review systematically summarizes the major optimization strategies for CRISPR‐Cas systems, focusing on the engineering of Cas proteins, guide RNAs, reporter probes, and the incorporation of chemical additives. The aim is to enhance editing precision and diagnostic capability, thereby expanding the CRISPR system's potential for broader biomedical ...
Sheng Li   +7 more
wiley   +1 more source

Epstein-Barr virus-associated lymphomas

open access: yes, 2004
Following Epstein and colleagues' ground-breaking discovery of Epstein-Barr virus by electron microscopy of Burkitt's lymphoma cell lines, there came the observation that Epstein-Barr virus induces immortalization of B cells in vitro. Thus, initial hopes
D Brooke Johnson   +4 more
core   +1 more source

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