Results 31 to 40 of about 5,502 (184)

Effects of two different glycoprotein platelet IIb/IIIa inhibitors and the clinical endpoints in patients with intracranial Pipeline flow diverter implant

Journal of Interventional Medicine, 2020
Objective: To compare the antiplatelet effect and major adverse cerebrovascular events of Pipeline for intracranial aneurysms using glycoprotein IIb/IIIa antagonists (GPI) eptifibatide and tirofiban.
Qiao Deng, Shichao Zhang, Mingzhou Li, Guozhong Zhang, Wenfeng Feng   +4 more
doaj   +1 more source

Eptifibatide use in ischemic stroke patients undergoing endovascular thrombectomy: A matched cohort analysis

Frontiers in Neurology, 2022
Introduction Small studies have suggested that eptifibatide (EPT) may be safe in acute ischemic stroke (AIS) following intravenous thrombolysis or during endovascular therapy (EVT) for large vessel occlusion (LVO).
Ameena Rana, Siyuan Yu, Savina Reid-Herrera, Scott Kamen, K. Hunter, H. Shaikh, T. Jovin, Olga R Thon, Parth Patel, J. Siegler, Jesse M. Thon   +10 more
semanticscholar   +1 more source

Eptifibatide-Induced Severe Thrombocytopenia After ST-Elevation Myocardial Infarction (STEMI): A Case Report

Cureus, 2022
Eptifibatide is a platelet glycoprotein (GP) IIb/IIIa inhibitor that is used in certain cases of acute coronary syndrome, including those with high thrombus burden or with no-reflow.
Zaid Gheith, Areej Kilani, Tam Nguyen
semanticscholar   +1 more source

Treatment of progressive ischemic stroke with low‑dose eptifibatide: A retrospective case‑control study

Experimental and Therapeutic Medicine, 2022
Progressive ischemic stroke (PIS) is a therapeutic challenge in clinical practice. The present retrospective study aimed to investigate the safety and effectiveness of eptifibatide in the treatment of PIS.
Longfeng Luo, Jinsheng Lin, Ye Deng, Zhigang Li, Ying Yuan, Wen Zhang   +5 more
semanticscholar   +1 more source

A NEW HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE SEPARATION AND SIMULTANEOUS QUANTIFICATION OF EPTIFIBATIDE AND ITS IMPURITIES IN PHARMACEUTICAL INJECTION FORMULATION

International Journal of Applied Pharmaceutics, 2021
Objective: The objective of the present study is to develop a stability-indicating reverse-phase high-performance liquid chromatography (RP-HPLC) method for qualitative and quantitative determination of Eptifibatide and its impurities in bulk and ...
K. S. Girija, Bikshal Babu Kasimala, Venkateswara Rao Anna   +2 more
semanticscholar   +1 more source

Eptifibatide-induced acute profound thrombocytopenia: A case report

Medicine, 2022
Rationale: Eptifibatide is an antiplatelet agent used in the medical management of acute coronary syndrome. Although multiple studies did not reveal a significant association between eptifibatide and the development of thrombocytopenia, recent case ...
Mohammed A. Alamin, A. Al-Mashdali, Dawoud I. Al Kindi, Elkhansa A. Elshaikh, Fahmi Othman   +4 more
semanticscholar   +1 more source

Eptifibatide bridging therapy for staged carotid artery stenting and cardiac surgery: Safety and feasibility

Vascular, 2022
Background Prophylactic carotid artery stenting (CAS) is an effective strategy to reduce perioperative stroke in patients with severe carotid stenosis who require cardiothoracic surgery (CTS).
M. Caton, K. Narsinh, A. Baker, M. Amans, S. Hetts, J. Rapp, J. Ianuzzi, E. Tseng, W. Gasper, D. Cooke, Travis Caton   +10 more
semanticscholar   +1 more source

In vitro and patient studies with platelets to explore off-target cardiovascular effects of integrase inhibitors. [PDF]

HIV Med
Abstract Introduction People with HIV currently face a tenfold higher risk of developing cardiovascular disease (CVD) than those without HIV. Studies have shown various off‐target effects of antiretroviral treatment (ART) on the cardiovascular system, but little is known about the effects of currently used integrase strand transfer inhibitors (INSTIs ...
Keniyopoullos R, Khawaja AA, Boffito M, Emerson M.   +3 more
europepmc   +2 more sources

The Pharmacological Effects of Silver Nanoparticles Functionalized with Eptifibatide on Platelets and Endothelial Cells

International Journal of Nanomedicine, 2022
Purpose In the search for new drug delivery platforms for cardiovascular diseases and coating of medical devices, we synthesized eptifibatide-functionalized silver nanoparticles (AgNPs-EPI) and examined the pharmacological activity of AgNPs-EPI on ...
Justyna Hajtuch, E. Iwicka, Anna Szczoczarz, D. Flis, E. Megiel, Piotr Cieciórski, M. Radomski, M. Santos-Martinez, I. Inkielewicz-Stępniak   +8 more
semanticscholar   +1 more source

How safe is eptifibatide during urgent carotid artery stenting?

Frontiers in Neurology, 2013
Background: Glycoprotein IIB/IIIA inhibitors are occasionally utilized during carotid artery stenting (CAS) in the presence or absence of a visualized intra-operative thrombus. Objective: We assess the hemorrhagic and clinical outcomes associated with
Hesham eAllam, Nirav eVora, Randall eEdgell, Richard Charles Callison, Yasir eAl Khalili, Michelle eStorkan, Amer eAlshekhlee, Amer eAlshekhlee   +7 more
doaj   +1 more source