Results 31 to 40 of about 5,685 (219)

Eptifibatide-Induced Severe Thrombocytopenia After ST-Elevation Myocardial Infarction (STEMI): A Case Report

open access: yesCureus, 2022
Eptifibatide is a platelet glycoprotein (GP) IIb/IIIa inhibitor that is used in certain cases of acute coronary syndrome, including those with high thrombus burden or with no-reflow.
Zaid Gheith, Areej Kilani, Tam Nguyen
semanticscholar   +1 more source

Early versus delayed, provisional eptifibatide in acute coronary syndromes [PDF]

open access: yes, 2009
BACKGROUND: Glycoprotein IIb/IIIa inhibitors are indicated in patients with acute coronary syndromes who are undergoing an invasive procedure. The optimal timing of the initiation of such therapy is unknown.
Giugliano, RP   +9 more
core   +2 more sources

Application of eptifibatide injection in acute ischemic cerebrovascular disease [PDF]

open access: yesXin yixue, 2022
Objective To evaluate the treatment effectiveness and safety of eptifibatide injection in the treatment of acute ischemic cerebrovascular disease (ICVD).
Mei Ni, Tian Liang
doaj   +1 more source

Drug-Induced Immune Thrombocytopenia Secondary to Trimethoprim-Sulfamethoxazole. [PDF]

open access: yesCase Rep Infect Dis
We report the case of a 55‐year‐old male with AIDS who developed severe thrombocytopenia following initiation of trimethoprim–sulfamethoxazole. Despite drug discontinuation and supportive measures, thrombocytopenia persisted, leading to the patient’s death.
Cimperman C   +6 more
europepmc   +2 more sources

Effects of two different glycoprotein platelet IIb/IIIa inhibitors and the clinical endpoints in patients with intracranial Pipeline flow diverter implant

open access: yesJournal of Interventional Medicine, 2020
Objective: To compare the antiplatelet effect and major adverse cerebrovascular events of Pipeline for intracranial aneurysms using glycoprotein IIb/IIIa antagonists (GPI) eptifibatide and tirofiban.
Qiao Deng   +4 more
doaj   +1 more source

Treatment of progressive ischemic stroke with low‑dose eptifibatide: A retrospective case‑control study

open access: yesExperimental and Therapeutic Medicine, 2022
Progressive ischemic stroke (PIS) is a therapeutic challenge in clinical practice. The present retrospective study aimed to investigate the safety and effectiveness of eptifibatide in the treatment of PIS.
Longfeng Luo   +5 more
semanticscholar   +1 more source

A NEW HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY METHOD FOR THE SEPARATION AND SIMULTANEOUS QUANTIFICATION OF EPTIFIBATIDE AND ITS IMPURITIES IN PHARMACEUTICAL INJECTION FORMULATION

open access: yesInternational Journal of Applied Pharmaceutics, 2021
Objective: The objective of the present study is to develop a stability-indicating reverse-phase high-performance liquid chromatography (RP-HPLC) method for qualitative and quantitative determination of Eptifibatide and its impurities in bulk and ...
K. Girija   +2 more
semanticscholar   +1 more source

Eptifibatide-induced acute profound thrombocytopenia: A case report

open access: yesMedicine, 2022
Rationale: Eptifibatide is an antiplatelet agent used in the medical management of acute coronary syndrome. Although multiple studies did not reveal a significant association between eptifibatide and the development of thrombocytopenia, recent case ...
Mohammed A. Alamin   +4 more
semanticscholar   +1 more source

The Pharmacological Effects of Silver Nanoparticles Functionalized with Eptifibatide on Platelets and Endothelial Cells

open access: yesInternational Journal of Nanomedicine, 2022
Purpose In the search for new drug delivery platforms for cardiovascular diseases and coating of medical devices, we synthesized eptifibatide-functionalized silver nanoparticles (AgNPs-EPI) and examined the pharmacological activity of AgNPs-EPI on ...
Justyna Hajtuch   +8 more
semanticscholar   +1 more source

Low-Dose Eptifibatide for Tandem Occlusion in Stroke: Safety and Carotid Artery Patency

open access: yesAmerican Journal of Neuroradiology, 2021
BACKGROUND AND PURPOSE: Maintaining carotid patency and avoiding symptomatic intracranial hemorrhage are competing concerns in tandem occlusions. This study provides data regarding the safety and efficacy of eptifibatide in stroke from tandem occlusion ...
A. Jost   +4 more
semanticscholar   +1 more source

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