Results 61 to 70 of about 3,772 (169)

FDA's stamp of approval: Unveiling peptide breakthroughs in cardiovascular diseases, ACE, HIV, CNS, and beyond

open access: yesJournal of Peptide Science, Volume 30, Issue 11, November 2024.
This review provides an overview of FDA‐approved peptides, particularly those targeting cardiovascular diseases, human immunodeficiency, and central nervous system diseases, and also addresses conditions such as osteoporosis, thrombocytopenia, Cushing's disease, and hypoglycemia.
Othman Al Musaimi
wiley   +1 more source

Therapeutic Plasma Exchange to Reverse Plasma Failure in Multiple Organ Dysfunction Syndrome

open access: yesJournal of Clinical Apheresis, Volume 39, Issue 5, October 2024.
ABSTRACT Plasma plays a crucial role in maintaining health through regulating coagulation and inflammation. Both are essential to respond to homeostatic threats such as traumatic injury or microbial infection; however, left unchecked, they can themselves cause damage.
Matthew J. Foglia   +3 more
wiley   +1 more source

Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

open access: yesCardiovascular Diabetology, 2008
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua   +3 more
doaj   +1 more source

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide

open access: yesFolia Histochemica et Cytobiologica, 2010
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz   +2 more
doaj  

Systematic adjudication of myocardial infarction end-points in an international clinical trial

open access: yesCurrent Controlled Trials in Cardiovascular Medicine, 2001
Background Clinical events committees (CEC) are used routinely to adjudicate suspected end-points in cardiovascular trials, but little information has been published about the various processes used.
Lee Kerry L   +16 more
doaj   +1 more source

Antiplatelet medications in acute coronary syndromes and percutaneous coronary interventions: focus on tirofiban

open access: yesКардиоваскулярная терапия и профилактика, 2008
The review presents literature data on the key role of platelet aggregation (PA) for intracoronary thrombogenesis in various acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI).
T. A. Batyraliev   +4 more
doaj  

Adjuvant antithrombotic therapy in ST-elevation myocardial infarction: A narrative review

open access: yesRevista Portuguesa de Cardiologia, 2019
This article reviews the major pharmacologic features of, and clinical evidence on, adjuvant medical therapy in patients with ST-elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention.
Daniel Caldeira, Hélder Pereira
doaj   +1 more source

Intracoronary Eptifibatide During Primary Percutaneous Coronary Intervention in Early Versus Late Presenters with ST Segment Elevation Myocardial Infarction: A Randomized Trial [PDF]

open access: gold, 2016
Ayman Elbadawi   +9 more
openalex   +1 more source

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