Results 61 to 70 of about 8,424 (263)

A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins [PDF]

open access: yes, 2017
Integrins, a diverse class of heterodimeric cell surface receptors, are key regulators of cell structure and behaviour, affecting cell morphology, proliferation, survival and differentiation.
Cavalcanti-Adam, Elisabetta Ada   +12 more
core   +2 more sources

CAN3: BASELINE COST OF ILLNESS OF PARKINSON'S DISEASE IN A LARGE HEALTHCARE PLAN [PDF]

open access: yes, 2000
We present a mixed finite element formulation for the spatial discretization in dynamic analysis of non-isothermal variably saturated porous media using different order of approximating functions for solid displacements and fluid pressures/temperature ...
Cao, Toan Duc   +3 more
core   +1 more source

Repeated Intravenous Thrombolysis in Patients with Recurrent Ischemic Stroke in the Vertebrobasilar Territory

open access: yesCase Reports in Neurology, 2021
Acute ischemic vertebrobasilar stroke (AIVBS) is usually associated with poor outcome and prognosis and in case of basilar artery occlusion (BAO) with high mortality.
David Černík   +3 more
doaj   +1 more source

P2Y12 Receptor Blockade Augments Glycoprotein IIb‐IIIa Antagonist Inhibition of Platelet Activation, Aggregation, and Procoagulant Activity [PDF]

open access: yes, 2014
Background: New antiplatelet agents that provide greater, more consistent inhibition of the platelet ADP receptor P2Y12 may be used in combination with glycoprotein (GP) IIb‐IIIa antagonists, but their combined effect on platelet function and ...
Barnard, Marc R.   +5 more
core   +1 more source

A unique, low dose of intravenous enoxaparin in elective percutaneous coronary intervention [PDF]

open access: yes, 2002
ObjectivesThis study was designed to examine a unique and low dose of intravenous enoxaparin in elective percutaneous coronary intervention (PCI) that would be applicable to an unselected population regardless of age, weight, renal function, or use of ...
Ankri, Annick   +8 more
core   +1 more source

Eptifibatide in Coronary Intervention [PDF]

open access: yesCirculation: Cardiovascular Interventions, 2015
Although percutaneous transluminal coronary intervention has revolutionized the management of patients with coronary artery disease, this technologic advance is neither innocuous nor a panacea. In addition to the technical limitations of the procedure, it is now well recognized that serious vascular injury is caused by the treatment device, which ...
Matthew W. Sherwood, James E. Tcheng
openaire   +3 more sources

Design of termo-sensitive molecularly imprinted polymers(MIP) and in vitro evaluation of controlled release of Eptifibatide drug [PDF]

open access: yesشیمی کاربردی روز
In this research, a nano polymer was fabricated via the molecular imprinted polymer (MINP) method to transport and control the release of the drug eptifibatide.
Sharif Kaamyabi   +2 more
doaj   +1 more source

Inhibition of platelet adhesion, thrombus formation, and fibrin formation by a potent αIIbβ3 integrin inhibitor from ticks

open access: yesResearch and Practice in Thrombosis and Haemostasis, 2021
Background Ticks puncture the skin of their hosts and secrete saliva, containing antiplatelet proteins, into the blood. Here, we studied disagregin, a potent platelet‐inhibiting protein derived from the salivary glands of Ornithodoros moubata, an African
Danique L. van denKerkhof   +6 more
doaj   +1 more source

CLINICAL CASE HISTORY OF EPTIFIBATIDE USE DURING CORONARY INTERVENTION IN PATIENT WITH CORONARY FAILURE

open access: yesРациональная фармакотерапия в кардиологии, 2015
Clinical case history of endovascular intervention in infarct related coronary artery with 4 sirolimus-eluting stents implantation and their further thrombosis during early postoperative period is described.
K. A. Kireev   +2 more
doaj   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu   +21 more
wiley   +1 more source

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