Results 61 to 70 of about 3,115 (154)

Relation of Level of Platelet Inhibition after Eptifibatide with Major Cardiovascular Events in ST-Segment Elevation Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Majalah Kardiologi Indonesia, 2015
Background: Eptifibatide, an inhibitor of glycoprotein IIb/IIIa administered as adjunctive therapy to reperfusion therapy Primary PCI in STEMI patients.
Elisa Feriyanti Pakpahan, Sunarya Soerianata, Nur Haryono   +2 more
doaj   +1 more source

A Critical Review on BH3 Mimetic Drugs and the Treatment of Cancer‐Associated Thrombosis (CAT): A Proposed Design for a Drug Delivery System Capable of Simultaneously Targeting Tumor Cells and Activated Platelets

Cancer Medicine, Volume 14, Issue 18, September 2025.
Targeting Cancer associated thrombosis (CAT): The left panel (A) shows cancer‐associated thrombosis with activated platelets expressing αIIbβ3 in close contact with tumoral vasculature expressing αvβ3 integrin, where both cells release a significant amount of thrombin.
Mehran Ghasemzadeh, Nazanin Heidari, Jalal Naghinezhad, Alireza Ghasemzadeh, Ehteramolsadat Hosseini   +4 more
wiley   +1 more source

Eptifibatide and abciximab inhibit insulin-induced focal adhesion formation and proliferative responses in human aortic smooth muscle cells

Cardiovascular Diabetology, 2008
Background The use of abciximab (c7E3 Fab) or eptifibatide improves clinical outcomes in diabetics undergoing percutaneous coronary intervention. These β3 integrin inhibitors antagonize fibrinogen binding to αIIbβ3 integrins on platelets and ligand ...
Huang Jianhua, Zhao Renyi, Pathak Alokkumar, Stouffer George A   +3 more
doaj   +1 more source

Antiplatelet medications in acute coronary syndromes and percutaneous coronary interventions: focus on tirofiban

Кардиоваскулярная терапия и профилактика, 2008
The review presents literature data on the key role of platelet aggregation (PA) for intracoronary thrombogenesis in various acute coronary syndromes (ACS) and percutaneous coronary interventions (PCI).
T. A. Batyraliev, D. V. Preobrazhensky, D. V. Fetzer, B. A. Sidorenko, S. A. Pataraya   +4 more
doaj  

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide

Folia Histochemica et Cytobiologica, 2010
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz, Anna Sankiewicz, Zbigniew A. Figaszewski   +2 more
doaj  

Addition of eptifibatide and manual thrombus aspiration to ticagrelor does not improve long-term survival after STEMI treated with primary PCI

Frontiers in Pharmacology
Background: Current guidelines recommend that glycoprotein IIb/IIIa inhibitor (GPI) and manual aspiration thrombectomy should not be routinely used in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous ...
Paul-Adrian Călburean, Paul-Adrian Călburean, Paul Grebenișan, Ioana-Andreea Nistor, Krisztina Pal, Krisztina Pal, Victor Vacariu, Reka-Katalin Drincal, Alissa Anamaria Ion, István Adorján, Tiberiu Oltean, László Hadadi   +11 more
doaj   +1 more source

Comparative efficacy of eptifibatide and abciximab in primary angioplasty study

Research Reports in Clinical Cardiology, 2011
Rohan Jayasinghe1 Matias Yudi1 Sanjay Jayasinghe21Cardiology Department, Gold Coast Hospital, Griffith University, Queensland, Australia; 2Centre for Immunisation Research, Sydney, AustraliaBackground: Primary percutaneous intervention is the safest and ...
Rohan Jayasinghe, Matias Yudi, Sanjay Jayasinghe   +2 more
doaj  

Endovascular treatment combined with eptifibatide in patients with acute ischemic stroke: a prospective, multicenter study

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the efficacy and safety of endovascular treatment (EVT) combined with eptifibatide in the treatment of acute ischemic stroke. Methods This study enrolled the 102 acute ischemic stroke patients at 15 centers in China received EVT ...
HU Xiao⁃yan, LUO Yu⁃qi, MIAO Yan, GAO Feng, MA Ning, SUN Xuan   +5 more
doaj   +1 more source

Safety and efficacy of adjunctive tirofiban and eptifibatide in acute ischemic stroke: A systematic review and meta-analysis

Journal of Stroke and Cerebrovascular Diseases
Introduction and Objective: Acute ischemic stroke (AIS) is one of the most common cerebrovascular diseases, posing a substantial burden on public health systems and individuals. Tirofiban and eptifibatide are used alongside intravenous thrombolysis (IVT)
Hameer Ali, Rida Shehzad, Usama Ahmed, Yahya Abualown, Wajida Perveen, Junaid Gulzar, Saad Azam, Zain ul Abideen, Shah e Zaman, Umair Hayat, Uzair Jafar, Muhammad Ehsan, Bilawal Nadeem, Ankit Agrawal, Raheel Ahmed   +14 more
doaj   +1 more source

Impact of Using Blended Polymers on the Structural and Functional Attributes of Eptifibatide-Loaded Microspheres. [PDF]

ACS Omega
Kyatanwar AU, Prabhakar BR.
europepmc   +1 more source