Results 61 to 70 of about 3,965 (158)

Assessment of Eptifibatide Clearance by Hemodialysis Using an in vitro System

, 2010
<i>Background/Aims:</i> Eptifibatide is a parenteral glycoprotein IIb-IIIa inhibitor that prevents platelet aggregation. Although contraindicated in dialysis patients due to limited safety and dialysis data, eptifibatide is prescribed in this
Christie A. Green, Elizabeth B. McNeely, Joanna Q. Hudson, Lisa K. Jennings   +3 more
core   +1 more source

Investigation of interaction of human platelet membrane components with anticoagulant drugs Abciximab and Eptifibatide

Folia Histochemica et Cytobiologica, 2010
Abciximab (Abci) and eptifibatide (Epti) are antiaggregate drugs which may reduce thrombotic complications inacute coronary syndromes. The aim of this work was the investigation of the interaction between the phospholipid-GPIIb/IIIa glycoprotein complex ...
Ewa Gorodkiewicz, Anna Sankiewicz, Zbigniew A. Figaszewski   +2 more
doaj  

Switch from abciximab to eptifibatide during percutaneous coronary intervention

, 2009
BACKGROUND: Treatment with glycoprotein (GP) IIb/IIIa inhibitors during percutaneous coronary intervention (PCI) reduce ischemic complications and improve outcome.
Grip, Lars,, Odell, Annika,, Tahmasebiepour, Farshad,, Karlsson, Thomas,, Matejka, Göran,, Albertsson, Per,, Wahlin, Magnus,, Wolmeryd, Christina,   +7 more
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Addition of eptifibatide and manual thrombus aspiration to ticagrelor does not improve long-term survival after STEMI treated with primary PCI

Frontiers in Pharmacology
Background: Current guidelines recommend that glycoprotein IIb/IIIa inhibitor (GPI) and manual aspiration thrombectomy should not be routinely used in patients with ST-segment elevation myocardial infarction (STEMI) treated by primary percutaneous ...
Paul-Adrian Călburean, Paul-Adrian Călburean, Paul Grebenișan, Ioana-Andreea Nistor, Krisztina Pal, Krisztina Pal, Victor Vacariu, Reka-Katalin Drincal, Alissa Anamaria Ion, István Adorján, Tiberiu Oltean, László Hadadi   +11 more
doaj   +1 more source

Fmoc Solid-phase Synthesis and Purification of Eptifibatide

, 2007
Eptifibatide是一种血小板糖蛋白GPⅡb/Ⅲa受体拮抗剂,临床研究结果显示其医用上的产业前景良好.采用Rink-Am-Resin树脂作为固相载体,Fmoc为保护策略固相合成了Eptifibatide.以DMF为反应溶剂,Piperidine-DMF脱去Fmoc保护基团,以TBTU/HOBt/DIEA作为肽键缩合试剂进行接肽反应,用TFA/EDT/TIS/H2O定量地从树脂上切除,制备型高效液相色谱分离纯化粗肽.同时对产品进行色谱分析和质谱鉴定.实验结果表明Fmoc合成策略中各步的缩合率均在95%
王宇, 陈亮, 熊瑛
core  

Eptifibatide bolus dose postductal stenting intervention: A single-center experience

Annals of Pediatric Cardiology
Objectives: Stent thrombosis, a potential complication of ductal stenting, is associated with high mortality. This is a catastrophic complication, which can occur acutely (within 24 h), subacutely (within 30 days), or late (≥30 days) after stent ...
Rishika Mehta, Amitabha Chattopadhyay, Aritra Mukherji, Sanjiban Ghosh, Jayita Nandy Das, Pushpanjali Gupta   +5 more
doaj   +1 more source

Eptifibatide-Induced Thrombocytopenia: With Thrombosis and Disseminated Intravascular Coagulation Immediately After Left Main Coronary Artery Percutaneous Coronary Angioplasty [PDF]

, 2012
Early clinical trials of eptifibatide did not show a significant association between eptifibatide and the development of thrombocytopenia, thrombosis, or disseminated intravascular coagulation.
Tempelhof, Michael W, Fintel, Dan, Benzuly, Keith H, Krichavsky, Marc Z   +3 more
core   +1 more source

Endovascular treatment combined with eptifibatide in patients with acute ischemic stroke: a prospective, multicenter study

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To explore the efficacy and safety of endovascular treatment (EVT) combined with eptifibatide in the treatment of acute ischemic stroke. Methods This study enrolled the 102 acute ischemic stroke patients at 15 centers in China received EVT ...
HU Xiao⁃yan, LUO Yu⁃qi, MIAO Yan, GAO Feng, MA Ning, SUN Xuan   +5 more
doaj   +1 more source

Safety and efficacy of adjunctive tirofiban and eptifibatide in acute ischemic stroke: A systematic review and meta-analysis

Journal of Stroke and Cerebrovascular Diseases
Introduction and Objective: Acute ischemic stroke (AIS) is one of the most common cerebrovascular diseases, posing a substantial burden on public health systems and individuals. Tirofiban and eptifibatide are used alongside intravenous thrombolysis (IVT)
Hameer Ali, Rida Shehzad, Usama Ahmed, Yahya Abualown, Wajida Perveen, Junaid Gulzar, Saad Azam, Zain ul Abideen, Shah e Zaman, Umair Hayat, Uzair Jafar, Muhammad Ehsan, Bilawal Nadeem, Ankit Agrawal, Raheel Ahmed   +14 more
doaj   +1 more source

Eptifibatide Bolus Dose During Elective Percutaneous Coronary Intervention

Background: Eptifibatide is a platelet glycoprotein IIb/IIIa receptor antagonist used for the prevention of cardiac ischemic complications of percutaneous coronary intervention (PCI). Eptifibatide has been used with bolus dose only or bolus plus infusion
دوستکامی, حسین, صادقیه اهری, سعید, ایرانی جم, عفت, حبیب زاده, افشین   +3 more
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