Results 171 to 180 of about 18,864 (234)

Real‐world completion of diabetes self management education and its impact on patient‐reported outcomes: A scoping review

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes self management education (DSME) is recommended for type 2 diabetes, with completion widely accepted as ≥60% engagement. This review utilising PRISMA extension for scoping reviews maps the literature on the impact of full and partial completion of DSME on patient‐reported outcomes (PROMs) versus a control.
Gemma Lewis, David M. Hughes, Greg Irving, John Wilding, Kevin Hardy   +4 more
wiley   +1 more source

Efficacy and Safety of Pregabalin and Alpha‐Lipoic Acid Combination in Patients With Painful Diabetic Peripheral Neuropathy: A Randomized, Open‐Label, Non‐Inferiority, Phase IV Clinical Trial and Subgroup Analysis (OPTIMUM Study)

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To assess the efficacy and safety of alpha‐lipoic acid (ALA) and pregabalin, both as mono and combination therapy, for treating painful diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus, with the hypothesis that pregabalin monotherapy is non‐inferior to combination therapy.
Tae Jung Oh, Sang Soo Kim, Seung‐Hwan Lee, Hyuk‐Sang Kwon, Eun Sook Kim, Eun‐Jung Rhee, Hye Jin Yoo, Han Na Jang, Woo Je Lee, Eun Sook Kim, Sang Yong Kim, Gwanpyo Koh, Eun‐Gyoung Hong, Tae Sun Park, Jong Chul Won   +14 more
wiley   +1 more source

A noncanonical role for Jagged1 in endothelial mechanotransduction

The FEBS Journal, EarlyView.
This study reveals a noncanonical role for Jagged1 in endothelial mechanotransduction. Shear stress modulates Jagged1 expression and subcellular localization. Loss of Jagged1 attenuates mechanotransduction and reduces Src, VEGFR2, and ERK signaling. Direct mechanical stimulation of Jagged1 induces activation of these signaling pathways.
Freddy Suarez Rodriguez, Noora Virtanen, Elmeri Kiviluoto, Rob C. H. Driessen, Feihu Zhao, Carlijn V. C. Bouten, Oscar M. J. A. Stassen, Cecilia M. Sahlgren   +7 more
wiley   +1 more source

Enhancing the Evidence for Care in Underserved Bleeding Disorders Communities

Haemophilia, EarlyView.
ABSTRACT Background Major advances in haemophilia care have not translated equitably across all populations. Individuals with rare bleeding disorders (RBDs), people living in low‐ and lower‐middle‐income countries (LMICs) and women and girls with inherited bleeding disorders (WGWBD) continue to face significant diagnostic, therapeutic and research ...
Johnny Mahlangu
wiley   +1 more source

Non‐Pharmacological Interventions for Cough in Patients With Lung Cancer: A Systematic Review and Meta‐Analysis

Journal of Clinical Nursing, EarlyView.
ABSTRACT Background Cough, a prevalent and debilitating symptom of lung cancer, remains poorly managed. Accumulating evidence on non‐pharmacological interventions for lung cancer cough necessitates systematic evaluation to assess their efficacy. Aim To synthesise evidence on non‐pharmacological interventions for managing cough in lung cancer patients ...
Mengyao Cao, Xueyan Cheng, Victor Ho‐fun Lee, Chia‐Chin Lin, Denise Shuk Ting Cheung   +4 more
wiley   +1 more source

HUBUNGAN KOMPONEN EQ-5D-3L DALAM PENILAIAN KUALITAS HIDUP PENERIMA VAKSIN SINOVAC® DI PELAYANAN KESEHATAN KOTA PALU [PDF]

Penerima vaksin Sinovac® di pelayanan kesehatan menjadi kelompok terdepan yang memiliki risiko tertinggi terjadinya penularan, sehingga menjadi prioritas utama dalam penerimaan vaksin.
Arief, Thendi Abdul, Hardani, Ririen, Rumi, Amelia   +2 more
core   +1 more source

Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia

Journal of Sleep Research, EarlyView.
ABSTRACT Insomnia may play a causal role in type 2 diabetes (T2D). Addressing insomnia through cognitive behavioural therapy (CBTi) in people with non‐diabetic hyperglycaemia could potentially reduce the risk of progression to T2D. To inform a future randomised trial, we performed a feasibility study of digital CBT (dCBTi) in individuals at increased ...
Rachel Sharman, David Ray, Andrew Farmer, Poppy C. E. Green, Victoria Harris, Fredrik Karpe, Colin A. Espie, Diana Mantripp, Thomas Marjot, Niall M. McGowan, Jeremy W. Tomlinson, Simon D. Kyle   +11 more
wiley   +1 more source

Impact of Infection Timing on Outcomes: A Comparative Study of Periprosthetic Joint and Fracture‐Related Infections

Orthopaedic Surgery, EarlyView.
I commend the authors on their efforts in developing a strong manuscript centered around an important topic, the trajectory of health‐related quality of life following PJI. Their statistical analyses have been significantly improved, and their findings are both novel and clinically relevant. Their discussion is succinct, thorough, and readable.
Lena Schwake, Jasper Frese, Arndt‐Peter Schulz, Sidney Schaeffer, Ulf‐Joachim Gerlach, Cornelius Grimme   +5 more
wiley   +1 more source

Population norms for the EQ-5D-3L and EQ-5D-5L in Peninsular Malaysia. [PDF]

Qual Life Res
Vasan Thakumar A, Li X, Shafie AA, Cheng LJ.   +3 more
europepmc   +1 more source

Cost‐effectiveness of the diabetes remission clinical trial (DiRECT)/Counterweight‐Plus weight management programme, based on 5‐year follow‐up

Diabetic Medicine, Volume 43, Issue 6, June 2026.
Abstract Aims Follow‐up of the Counterweight‐Plus intervention in DiRECT has demonstrated 6.1 kg weight loss and 10 % remissions from type 2 diabetes at 5 years. We previously reported cost‐effectiveness based on 2‐year results. We now present an updated cost‐effectiveness analysis, based on available 5‐year data.
A. Davies, E. Grieve, L. McCombie, A. McIntosh, A. McConnachie, W. S. Leslie, N. Sattar, R. Taylor, M. E. J. Lean   +8 more
wiley   +1 more source