Results 181 to 190 of about 127,286 (242)

Factors associated with health state valuations: a secondary analysis of an EQ-5D-3L valuation study from Jordan. [PDF]

Qual Life Res
Al Rabayah A, Al Sayah F, Arvandi M, Siebert U.   +3 more
europepmc   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

Addiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock, Krista J. Siefried, Gill Bedi, Steven Albert, Richard O. Day, Nadine Ezard, Margaret Ross, Paul Liknaitzky, Jonathan Brett   +8 more
wiley   +1 more source

Variations in health-related quality of life across sociodemographic groups, health conditions, and modifiable risk factors: a population-based EQ-5D-3L study. [PDF]

Health Qual Life Outcomes
Gebreslassie M, Fors S, Tynelius P, Janssen MF, Sveréus S, Heintz E.   +5 more
europepmc   +1 more source

Male Mice Heterozygous for Protamine 1 and Protamine 2 Are Infertile, Displaying Sperm Damage and Retention of Protamine 2 Precursors, Transition Proteins, and Histones

Andrology, EarlyView.
ABSTRACT Background During spermiogenesis, protamines (PRMs) replace histones to hypercondense and protect sperm DNA. Rodents and primates express two PRMs (PRM1 and PRM2). Alterations of species‐specific PRM ratios are associated with sub‐ or infertility in mice and humans.
Gina Esther Merges, Christoph Wiesejahn, Mar Domingo‐Lopez, Simon Schneider, Andjela Kovacevic, Lena Arévalo, Hubert Schorle   +6 more
wiley   +1 more source

Health-related quality of life and influencing factors in osteoporosis patients: A cross-sectional study based on the EQ-5D-3L Scale in China. [PDF]

Turk J Phys Med Rehabil
Bihui B, Xingwen X, Dingpeng L, Demin L, Fei Y.   +4 more
europepmc   +1 more source

Health‐related quality of life and patient‐reported outcome measures in economic evaluation of urological technologies: challenges and opportunities

BJU International, EarlyView.
Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi, Charlotte Moss, Netty Kinsella, Kathie Alexina Wong, Mieke Van Hemelrijck   +4 more
wiley   +1 more source

Measuring health-related quality of life in multiple sclerosis: comparing the acceptability, validity and responsiveness of the EQ-5D-3L and MSIS-8D. [PDF]

Qual Life Res
Goodwin E, Michalowsky B, Middleton R, Hawton A.   +3 more
europepmc   +1 more source

Ammonia Accumulation Drives Intervertebral Disc Degeneration by Triggering Ammonia‐Induced Cell Death Through Lysosome–Mitochondria Crosstalk

Cell Proliferation, EarlyView.
Mechanical strain disrupts the lysosome‐mitochondria axis via GLS1‐mediated ammonia toxicity, causing NP cell death and ECM breakdown in IVDD. CB839‐mediated GLS1 inhibition effectively rescues cellular homeostasis and alleviates disc degeneration.
Yang Zhang, Yucheng Gao, Shuhang Dong, Shuanggong Liu, Lei Liu, Ziyi Song, Jie Xu, Yijun Rong, Guangxu Song, Yingze Zhang, Dongjin Wu, Zengxin Gao   +11 more
wiley   +1 more source

Real‐world completion of diabetes self management education and its impact on patient‐reported outcomes: A scoping review

Diabetic Medicine, EarlyView.
Abstract Aims Diabetes self management education (DSME) is recommended for type 2 diabetes, with completion widely accepted as ≥60% engagement. This review utilising PRISMA extension for scoping reviews maps the literature on the impact of full and partial completion of DSME on patient‐reported outcomes (PROMs) versus a control.
Gemma Lewis, David M. Hughes, Greg Irving, John Wilding, Kevin Hardy   +4 more
wiley   +1 more source

Revisiting health state preferences after 20 years: A new EQ-5D-3L value set for the Netherlands. [PDF]

Eur J Health Econ
Roudijk B, Jonker MF.
europepmc   +1 more source