Results 171 to 180 of about 104,696 (276)

Impact of biological/targeted versus conventional synthetic disease‐modifying antirheumatic drugs on patient‐reported outcomes in rheumatoid arthritis

Rheumatology &Autoimmunity, EarlyView.
Patient‐reported outcomes (PROs) were compared among rheumatoid arthritis patients who maintained low disease activity or remission for at least 6 months based on the disease‐modifying antirheumatic drug (DMARD)administered. Even with comparable disease activity, methotrexate (MTX) group, biological/targeted synthetic DMARDs (b/tsDMARDs), particularly ...
Masafumi Sugiyama, Saki Okuda‐Tsuchimoto, Takashi tsuchimoto, Koji Kinoshita, Itaru Matsumura   +4 more
wiley   +1 more source

Thai Translation and Validation of Chronic Rhinosinusitis‐Patient Reported Outcome (CRS‐PRO)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objectives The Chronic Rhinosinusitis Patient‐Reported Outcome (CRS‐PRO) questionnaire was recently developed for use in chronic rhinosinusitis (CRS) patients. This instrument was developed using current diagnostic criteria. This study aimed to translate and validate CRS‐PRO for Thai CRS patients.
Wirach Chitsuthipakorn, Vorachai Pooldum, Juthaporn Phetpong, Saranath Lawpoolsri, Dichapong Kanjanawasee, Patlada Kowatanamongkon, Kittichai Mongkolkul, Kachorn Seresirikachorn, Kornkiat Snidvongs   +8 more
wiley   +1 more source

Targeting Inflammatory Alarmin S100A9 Modulates Activation of Pro‐Inflammatory Macrophage to Protect Nasal Epithelial Cells From LPS‐Induced Epithelial–Mesenchymal Transition

Microbiology and Immunology, EarlyView.
ABSTRACT Chronic rhinosinusitis with nasal polyps (CRSwNP) exhibits pronounced endotypic heterogeneity, with macrophages serving as key drivers of sustained mucosal inflammation. In this study, we identify S100A9 as a macrophage‐derived alarmin that is markedly elevated in CRSwNP tissues.
Yunxiang Ji, Jia Luan, Fang Yuan, Zhao Wang, Ran Wei, Guangbin Sun   +5 more
wiley   +1 more source

Vaginal Hysterectomy Versus Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery Hysterectomy; Results of a Randomised Controlled Trial

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To compare Vaginal Hysterectomy (VH) with Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery (NOTES) hysterectomy (VANH) as a day‐care procedure. Design Single‐blind, multicentre randomised controlled trial. Setting Two Dutch non‐academic teaching hospitals.
Ilse P. W. Bekkers, Floor R. M. Wintraecken, Nicol A. C. Smeets, Anne Damoiseaux, Jacques W. M. Maas, Huib A. A. M. van Vliet, Martine M. L. H. Wassen   +6 more
wiley   +1 more source

The EQ-5D-5L valuation study in Nigeria. [PDF]

Qual Life Res
Yusuf AH, Ardo BU, Thavorncharoensap M, Roudijk B, Purba FD, Yang Z, Liao M, Chaikledkaew U, Youngkong S, Thakkinstian A, Agada-Amade YA, Amole TG, Sambo MN, Ohiri K.   +13 more
europepmc   +1 more source

Examining the health-related quality of life using EQ-5D-5L in patients with four kinds of chronic diseases from specialist outpatient clinics in Hong Kong SAR, China

, 2017
Richard Huan Xu, Annie Wai Ling Cheung, Eliza Lai-Yi Wong The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China Background: Health-related quality of life (HRQoL ...
Cheung AWL, Xu RH, Wong ELY
core  

Cost‐Effectiveness Analysis of Transoral Robotic Surgery Versus Radiotherapy Alone for Early‐Stage HPV‐Associated Oropharynx Squamous Cell Carcinoma in Australia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Introduction Transoral robotic surgery (TORS) and radiotherapy are both recognised as effective treatment options for early‐stage HPV‐associated oropharyngeal squamous cell carcinoma (HPV‐OPSCC). TORS offers the benefit of a shorter total treatment duration; however, a proportion of patients require adjuvant radiotherapy with or without ...
Lan Gao, June Corry, Danny Rischin, Tao Xing   +3 more
wiley   +1 more source

Mapping the mRS Into the EQ-5D-5L in Patients With Ischemic Stroke. [PDF]

Stroke
Pinckaers FME, Grutters JPC, Evers SMAA, Lingsma HF, Boogaarts HD, Dippel DWJ, Postma AA, van der Lugt A, Majoie CBLM, Roos YBWEM, van Oostenbrugge RJ, van Zwam WH, Gabrio A.   +12 more
europepmc   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

EQ-5D-5L population norms for Singapore: a household survey-based analysis. [PDF]

Qual Life Res
Xiamusiya A, Lee JJ, Shou Y, Hao S, Subramaniam M, Cheng LJ, Luo N.   +6 more
europepmc   +1 more source