Results 241 to 250 of about 134,162 (275)

Shear Stress‐Stimulated Trafficking of Endothelial Piezo1 to Splenic Capsule Boosts Spleen Contraction and Exercise Endurance

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
The vasculo‐splenic axis during exercise: shear stress triggers the release of medium/large extracellular vesicles from vascular endothelial cells via activation of Piezo1, shuttling Piezo1 to the smooth muscle cells in the splenic capsule; the translocated Piezo1 within the splenic capsule acts as a downstream effector of the α1‐adrenergic receptor ...
Jing Lou   +12 more
wiley   +1 more source

Provox Life HMEs for Pulmonary Rehabilitation in HME‐Naïve Laryngectomy Patients: A Randomized Controlled Trial

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
ABSTRACT Objective To evaluate whether Provox Life Heat and Moisture Exchangers (HMEs) and attachments enable HME‐naïve laryngectomized patients to establish a 24‐h HME routine, and whether the resulting effect on pulmonary symptoms is sustained over 9 months, compared with standard care. Methods In this prospective, randomized controlled trial, 79 HME‐
Rafael De Cicco   +9 more
wiley   +1 more source

Variations in quality of life in people with multimorbidity: A cross-sectional survey comparing MMQ1 and EQ-5D-5L. [PDF]

open access: yesJ Multimorb Comorb
Sweeney KD   +6 more
europepmc   +1 more source

Safety and Effectiveness of a Bioabsorbable Septal Implant for Cartilaginous Nasal Septal Deviation

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
This study aims to evaluate the safety and effectiveness of a bioabsorbable submucosal septal implant (SeptAlign; Spirair Inc.) for minimally invasive correction of cartilaginous nasal septal deviation (NSD). In 80 subjects (92.5% with moderate‐to‐severe NSD), NOSE scores decreased by 63.2% (from 67.5 at baseline to 26.0 at 3 months and 23.6 at 6 ...
Thomas S. Higgins   +7 more
wiley   +1 more source

Vaginal Hysterectomy Versus Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery Hysterectomy; Results of a Randomised Controlled Trial

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, Volume 133, Issue 11, Page 2035-2043, October 2026.
ABSTRACT Objective To compare Vaginal Hysterectomy (VH) with Vaginal Assisted Natural Orifice Transluminal Endoscopic Surgery (NOTES) hysterectomy (VANH) as a day‐care procedure. Design Single‐blind, multicentre randomised controlled trial. Setting Two Dutch non‐academic teaching hospitals.
Ilse P. W. Bekkers   +6 more
wiley   +1 more source

Pulmonary artery catheters or central venous catheters for cardiac surgery: the PUMA Pilot randomised clinical trial

open access: yesAnaesthesia, Volume 81, Issue 10, Page 1358-1366, October 2026.
Summary Introduction Pulmonary artery catheters are used widely in cardiac surgery despite observed associations with worse outcomes and guidelines that recommend against their routine use. No adequately powered randomised trials are available. Methods The PUMA Pilot was a multicentre, randomised, parallel assignment, open‐label, pilot and feasibility ...
Luke A. Perry   +22 more
wiley   +1 more source

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