Results 51 to 60 of about 128,279 (290)

Adding a fatigue item to the EQ-5D-5L improves its psychometric performance in the general population

Journal of Patient-Reported Outcomes, 2022
Background Fatigue is a common and often disturbing sequela of serious chronic health conditions. In the widely applied HRQL instrument, the EQ-5D, this aspect is not included directly, for its assumed lack of additional information.
Inge Spronk, Suzanne Polinder, Gouke J. Bonsel, M. F. Janssen, Juanita A. Haagsma   +4 more
doaj   +1 more source

Patients as partners in a research advisory council role: describing the APERSU Patient Engagement Network

Journal of Patient-Reported Outcomes
Patient and public involvement and engagement (PPIE) is crucial for developing patient-centered healthcare research and improving health outcomes. While patient-reported outcome measures (PROMs) capture patients’ perspectives, meaningfully engaging ...
Sadia Ahmed, Marcia Bruce, D’Arcy Duquette, Veronika Kiryanova, Meron Seyoum, Simron Sidhu, Gloria Wilkinson, Fatima Al Sayah, Jeffrey A. Johnson, Arto Ohinmaa, Allison Soprovich   +10 more
doaj   +1 more source

EQ-5D: a plea for accurate nomenclature

Journal of Patient-Reported Outcomes, 2020
Between 1987 and 1990, the EuroQol Group developed a 5-dimension health-related quality of life instrument, originally known as ‘the EuroQol instrument’, which since 1995 has been called the ‘EQ-5D’. For several years, ‘the EuroQol instrument’ and ‘EQ-5D’
Richard Brooks, Kristina S. Boye, Bernhard Slaap   +2 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

A pilot study on the validity and psychometric properties of the electronic EQ-5D-5L in routine clinical practice

Health and Quality of Life Outcomes, 2021
Background Electronic measurement of health-related quality of life (HRQOL) may facilitate timely and regular assessments in routine clinical practice. This study evaluated the validity and psychometric properties of an electronic version of the EQ-5D-5L
Cindy Lo Kuen Lam, Emily Tsui Yee Tse, Carlos King Ho Wong, Joyce Sau Mei Lam, Sikky Shiqi Chen, Laura Elizabeth Bedford, Jason Pui Yin Cheung, Calvin Kalun Or, Paul Kind   +8 more
doaj   +1 more source

Preparatory study for the revaluation of the EQ-5D tariff: methodology report. [PDF]

, 2014
BACKGROUND: EQ-5D is a widely used generic measure of health with a 'tariff', or preference weights, obtained from the general population, using time trade-off (TTO).
Bansback, Nick, Brazier, John, Buckingham, Ken, Cairns, John, Devlin, Nancy, Dolan, Paul, Hole, Arne Risa, Kavetsos, Georgios, Longworth, Louise, Mulhern, Brendan, Rowen, Donna, Tsuchiya, Aki   +11 more
core   +3 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Correspondence between EQ-5D health state classifications and EQ VAS scores [PDF]

, 2008
Background The EQ-5D health-related quality of life instrument comprises a health state classification followed by a health evaluation using a visual analogue scale (VAS).
David K Whynes
core   +1 more source

Correction to: Comparing the UK EQ-5D-3L and English EQ-5D-5L Value Sets [PDF]

PharmacoEconomics, 2018
The article Comparing the UK EQ-5D-3L and English EQ-5D-5L Value Sets, written by Brendan Mulhern, Yan Feng, Koonal Shah, Mathieu F. Janssen, Michael Herdman, Ben van Hout, Nancy Devlin was originally published electronically on the publisher's internet portal (currently SpringerLink) on February 23, 2018 without open access.
Brendan Mulhern, Yan Feng, Koonal Shah, Mathieu F. Janssen, Michael Herdman, Ben van Hout, Nancy Devlin   +6 more
openaire   +3 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source