Results 51 to 60 of about 188,097 (293)

Perbandingan EQ-5D-5L dan SF-6D Untuk Mengukur Index Utility Kesehatan Pada Populasi Umum di Yogyakarta

Jurnal Manajemen dan Pelayanan Farmasi, 2020
The EuroQuality of life-5 dimension 5 level (EQ-5D-5L) and Short Form-6 Dimension (SF-6D) are the most widely used generic instruments for assessing utility as an outcome parameter in pharmacoeconomic studies.
Tri Murti Andayani, Dwi Endarti, Susi Ari Kristina, Anindya Rahmawati   +3 more
doaj   +1 more source

The clinical relevance of quality of life in heart failure patients with preserved ejection fraction

ESC Heart Failure, 2023
Aims Patient reported outcomes (PROs) are gradually being incorporated into daily practice to assess individual health‐related quality of life (QOL).
Masahiro Seo, Tetsuya Watanabe, Takahisa Yamada, Masamichi Yano, Takaharu Hayashi, Akito Nakagawa, Yusuke Nakagawa, Shunsuke Tamaki, Yoshio Yasumura, Yohei Sotomi, Shungo Hikoso, Daisaku Nakatani, Masatake Fukunami, Yasushi Sakata, the Osaka CardioVascular Conference (OCVC)‐Heart Failure investigators   +14 more
doaj   +1 more source

Patients as partners in a research advisory council role: describing the APERSU Patient Engagement Network

Journal of Patient-Reported Outcomes
Patient and public involvement and engagement (PPIE) is crucial for developing patient-centered healthcare research and improving health outcomes. While patient-reported outcome measures (PROMs) capture patients’ perspectives, meaningfully engaging ...
Sadia Ahmed, Marcia Bruce, D’Arcy Duquette, Veronika Kiryanova, Meron Seyoum, Simron Sidhu, Gloria Wilkinson, Fatima Al Sayah, Jeffrey A. Johnson, Arto Ohinmaa, Allison Soprovich   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Preparatory study for the revaluation of the EQ-5D tariff: methodology report. [PDF]

, 2014
BACKGROUND: EQ-5D is a widely used generic measure of health with a 'tariff', or preference weights, obtained from the general population, using time trade-off (TTO).
Tsuchiya, Aki, Devlin, Nancy, John Brazier, Bansback, N., Brendan Mulhern, Bansback, N, Brazier, J, Rowen, Donna, Rowen, D, Mulhern, B., Rowen, D., Georgios Kavetsos, Hole, AR, Kavetsos, G., Donna Rowen, Buckingham, K., Nancy Devlin, Mulhern, Brendan, Brazier, John, Dolan, Paul, Kavetsos, G, Cairns, J, Buckingham, Ken, Cairns, J., Cairns, John, Hole, A.R., Longworth, Louise, Arne Risa Hole, Mulhern, B, John Cairns, Tsuchiya, A., Devlin, N., Aki Tsuchiya, Brazier, J., Paul Dolan, Nick Bansback, Dolan, P, Devlin, N, Hole, Arne Risa, Dolan, P., Tsuchiya, A, Buckingham, K, Louise Longworth, Bansback, Nick, Longworth, L., Ken Buckingham, Longworth, L, Kavetsos, Georgios   +47 more
core   +1 more source

Proportion of missing values per dimension/item for the EQ-5D-5L, EQ-5D-3L and WHOQOL-OLD.

, 2023
Proportion of missing values per dimension/item for the EQ-5D-5L, EQ-5D-3L and WHOQOL-OLD.
Wolfgang Greiner (34442), Ole Marten (6727244)   +1 more
core   +1 more source

Stakeholders’ perspectives on implementing and integrating patient-reported outcome measures (PROMs) in health systems - insights from Alberta, Canada

Journal of Patient-Reported Outcomes
Background Patient-reported outcome measures (PROMs) are valuable tools for evaluating outcomes of healthcare interventions and have been increasingly used in health systems around the world.
Fatima Al Sayah, Hilary Short, Arto Ohinmaa, Stafford Dean, Brenda Hubley, Markus Lahtinen, Jeffrey A. Johnson   +6 more
doaj   +1 more source

Exploring the relation between the EQ-5D-5L pain/discomfort and pain and itching in a sample of burn patients

Health and Quality of Life Outcomes, 2020
Background The EQ-5D domain pain/discomfort (PD) uses one item to capture pain and other aspects of discomfort, like itching. This study explored how pain, itching and the EQ-5D-5L PD domain relate to each other in a sample of burn patients.
I. Spronk, G. J. Bonsel, S. Polinder, M. E. van Baar, M. F. Janssen, J. A. Haagsma   +5 more
doaj   +1 more source