Results 61 to 70 of about 128,279 (290)

Using Patient‐Reported Outcomes in Two Program Examples Measuring Health Status in Primary Care: An Observational Study

Health Science Reports
Background and Aims Patient‐reported outcome measures (PROMs) are increasingly used in primary care practices; however, the broad characteristics of this population pose unique challenges. Generic PROMs (e.g., EQ‐5D‐5L) measure general health status from
Allison L. Soprovich, Hilary Short, Al‐Bakir Ali, Krista Brower, Arto Ohinmaa, Jeffrey A. Johnson   +5 more
doaj   +1 more source

Exploring the relation between the EQ-5D-5L pain/discomfort and pain and itching in a sample of burn patients

Health and Quality of Life Outcomes, 2020
Background The EQ-5D domain pain/discomfort (PD) uses one item to capture pain and other aspects of discomfort, like itching. This study explored how pain, itching and the EQ-5D-5L PD domain relate to each other in a sample of burn patients.
I. Spronk, G. J. Bonsel, S. Polinder, M. E. van Baar, M. F. Janssen, J. A. Haagsma   +5 more
doaj   +1 more source

EQ-5D visual analog scale and utility index values in individuals with diabetes and at risk for diabetes: Findings from the Study to Help Improve Early evaluation and management of risk factors Leading to Diabetes (SHIELD) [PDF]

, 2008
Background The EQ-5D was used to compare burden experienced by respondents with diabetes and those at risk for diabetes. Methods A survey including the EQ-5D was mailed to individuals with self-reported diabetes, as well as those without diabetes but ...
Susan Grandy, Kathleen M Fox
core   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Stakeholders’ perspectives on implementing and integrating patient-reported outcome measures (PROMs) in health systems - insights from Alberta, Canada

Journal of Patient-Reported Outcomes
Background Patient-reported outcome measures (PROMs) are valuable tools for evaluating outcomes of healthcare interventions and have been increasingly used in health systems around the world.
Fatima Al Sayah, Hilary Short, Arto Ohinmaa, Stafford Dean, Brenda Hubley, Markus Lahtinen, Jeffrey A. Johnson   +6 more
doaj   +1 more source

Validation of the EQ-5D in Taiwan using item response theory

BMC Public Health, 2021
Background Our study aims to provide validity evidence for the EuroQol five dimensions questionnaire (EQ-5D) in the National Health Interview Survey of Taiwan in the 2013 wave and further interpret the EQ-5D scores for patients with chronic diseases ...
Tzu-Hung Liu, Andrew D. Ho, Yu-Tien Hsu, Chih-Cheng Hsu   +3 more
doaj   +1 more source

Examining the incremental impact of long-standing health conditions on subjective well-being alongside the EQ-5D [PDF]

, 2014
Background: Generic preference-based measures such as the EQ-5D and SF-6D have been criticised for being narrowly focused on a sub-set of dimensions of health. Our study aims to explore whether long-standing health conditions have an incremental impact
Blackburn, J., Brazier, J., Cooper, C., Relton, C., Smith, C., Wu, M.   +5 more
core   +3 more sources

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

General population reference values for 3-level EQ-5D (EQ-5D-3L) questionnaire in Poland [PDF]

Polish Archives of Internal Medicine, 2015
A Polish EQ-5D normative study published in 2010 was conducted in 2008 as a pilot study. The group of respondents was relatively small and had limited representativeness.The aim of the study was to derive population norms for the 3-level EQ-5D (EQ-5D-3L) questionnaire in Poland using a large, representative sample.Stratified random sampling was used. A
Dominik, Golicki, Maciej, Niewada
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source