Global analyses of genomic and epigenomic influences on gene expression reveal <i>Serpina3n</i> as a major regulator of cardiac gene expression in response to catecholamine challenge during heart failure. [PDF]
EpigeneticsLahue C +4 more
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Identification of mitochondrial dynamics-related biomarkers in psoriasis using bioinformatics and Mendelian randomization. [PDF]
Medicine (Baltimore)Zhang B, Shi J, Jiang J, Zhang L.
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Colocalization of GWAS and eQTL Signals Detects Target Genes
bioRxiv, 2016 F. Hormozdiari +9 more
semanticscholar +1 more source
Pleiotropy and Facilitation of Local Adaptation in the Silverleaf Sunflower Helianthus argophyllus. [PDF]
Genome Biol EvolOkinedo UE, Moyers BT.
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PRISM-xQTL: Pleiotropic Relationships Integrated with System-level Multiomic QTL analysis for causal genes and molecular mediators in Alzheimer's disease. [PDF]
Alzheimers DementEnduru N, Zhao Z.
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Integrative analysis of quantitative trait loci of alternative polyadenylation and GWAS highlights key regulators of milk production and immune traits in Holstein. [PDF]
Anim GenetTao X +6 more
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Transcriptome data combined with two-sample Mendelian randomization reveal IRF1 and PRKD1 as UPR-related key regulators in intervertebral disc degeneration. [PDF]
Medicine (Baltimore)Zheng F +7 more
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Systematic Druggable Genome-Wide Analysis Identifies Therapeutic Targets for Aging: A Mendelian Randomization Study. [PDF]
Health Sci RepZhang Y +10 more
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Approximate Bayesian inference of directed acyclic graphs in biology with flexible priors on edge states. [PDF]
PLoS Comput BiolMartin EA, Patchigolla V, Fu AQ.
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Full-length transcriptome atlas of porcine skeletal muscle reveals isoform-resolved genetic regulatory mechanisms for muscle growth. [PDF]
BMC GenomicsHu J, Ding Z, Yao T, Zou X, Wu Z.
europepmc +1 more source